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Endothelin Converting Enzyme 1 (ECE1)

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Endothelin Converting Enzyme 1 (ECE1)
CCC A483
HGNC 3146
MGI 1101357
PubMed 8359888
RGD 620293
UniProt P42892
Wiki ECE1

Endothelin converting enzyme 1, also known as ECE1, is a enzyme which in humans is encoded by the ECE1 gene.Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1), -2 (EDN2), and -3 (EDN3) to biologically active peptides.

Schmidt et al. (1994) purified a membrane-bound protease activity from bovine endothelial cells that specifically converts the inactive form to EDN1. The enzyme was cleaved with trypsin and peptide sequencing analysis confirmed it to be a zinc-chelating metalloprotease containing the typical HEXXH (HELTH) motif. RT-PCR and cDNA screens were used to isolate the complete cDNAs of the bovine and human enzymes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA483Hu01 Recombinant Endothelin Converting Enzyme 1 (ECE1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA483Hu01 Polyclonal Antibody to Endothelin Converting Enzyme 1 (ECE1) WB; IHC; ICC; IP.
MAA483Hu22 Monoclonal Antibody to Endothelin Converting Enzyme 1 (ECE1) WB; IHC; ICC; IP.
Assay Kits SEA483Hu ELISA Kit for Endothelin Converting Enzyme 1 (ECE1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA483Mu01 Recombinant Endothelin Converting Enzyme 1 (ECE1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA483Mu01 Polyclonal Antibody to Endothelin Converting Enzyme 1 (ECE1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Endothelin Converting Enzyme 1 (ECE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endothelin Converting Enzyme 1 (ECE1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA483Ra01 Recombinant Endothelin Converting Enzyme 1 (ECE1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA483Ra01 Polyclonal Antibody to Endothelin Converting Enzyme 1 (ECE1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Endothelin Converting Enzyme 1 (ECE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endothelin Converting Enzyme 1 (ECE1) ELISA Kit Customized Service Offer
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