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Elastin Microfibril Interface Located Protein 1 (EMILIN1)

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EMI; gp115; Elastin Microfibril Interfacer 1

Elastin Microfibril Interface Located Protein 1 (EMILIN1)
CCC A415
HGNC 19880
MGI 1926189
PubMed 17074837
RGD 1311209
UniProt Q9Y6C2
Wiki EMILIN1

EMILIN (elastin microfibril interface located protein) is an extracellular matrix glycoprotein abundantly expressed in elastin-rich tissues such as blood vessels, skin, heart, and lung.

The extracellular matrix protein EMILIN1 (elastin microfibril interface located protein 1) is implicated in maintaining blood pressure homeostasis via the N-terminal elastin microfibril interface domain and in trophoblast invasion of the uterine wall via the globular C1q (gC1q) domain. Elastin microfibril interface-located proteins (EMILINs) constitute a family of extracellular matrix (ECM) glycoproteins characterized by the presence of an EMI domain at the N terminus and a gC1q domain at the C terminus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA415Hu01 Recombinant Elastin Microfibril Interface Located Protein 1 (EMILIN1) Positive Control; Immunogen; SDS-PAGE; WB.
APA415Hu01 Active Elastin Microfibril Interface Located Protein 1 (EMILIN1) Cell culture; Activity Assays.
Antibodies PAA415Hu01 Polyclonal Antibody to Elastin Microfibril Interface Located Protein 1 (EMILIN1) WB; IHC; ICC; IP.
MAA415Hu22 Monoclonal Antibody to Elastin Microfibril Interface Located Protein 1 (EMILIN1) WB; IHC; ICC; IP.
Assay Kits SEA415Hu ELISA Kit for Elastin Microfibril Interface Located Protein 1 (EMILIN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA415Mu01 Recombinant Elastin Microfibril Interface Located Protein 1 (EMILIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA415Mu01 Polyclonal Antibody to Elastin Microfibril Interface Located Protein 1 (EMILIN1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Elastin Microfibril Interface Located Protein 1 (EMILIN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Elastin Microfibril Interface Located Protein 1 (EMILIN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA415Ra01 Recombinant Elastin Microfibril Interface Located Protein 1 (EMILIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA415Ra01 Polyclonal Antibody to Elastin Microfibril Interface Located Protein 1 (EMILIN1) WB; IHC; ICC; IP.
Assay Kits SEA415Ra ELISA Kit for Elastin Microfibril Interface Located Protein 1 (EMILIN1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins."J. Biol. Chem. 274:16773-16781(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Structure, chromosomal localization, and promoter analysis of the human elastin microfibril interface located protein (EMILIN) gene."J. Biol. Chem. 275:785-792(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily."J. Biol. Chem. 276:12003-12011(2001) [PubMed] [Europe PMC] [Abstract]
  7. "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."Mol. Cell. Proteomics 5:226-233(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  10. "NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1."J. Biomol. NMR 43:79-96(2009) [PubMed] [Europe PMC] [Abstract]