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Vasoactive Intestinal Peptide (VIP)

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PHM27; Intestinal peptide PHV-42; Peptide histidine valine 42; Peptide histidine methioninamide 27

Vasoactive Intestinal Peptide (VIP)
CCC A380
HGNC 12693
MGI 98933
PubMed 11121793
RGD 621647
UniProt P01282
Wiki VIP

Vasoactive intestinal peptide (VIP) is a peptide hormone containing 28 amino acid residues and is produced in many areas of the human body including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain.It has a half-life in the blood of about two minutes. With respect to the digestive system, VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile, and cause inhibition of gastric acid secretion and absorption from the intestinal lumen. Its role in the intestine is to greatly stimulate secretion of water and electrolytes, as well as dilating intestinal smooth muscle, dilating peripheral blood vessels, stimulating pancreatic bicarbonate secretion, and inhibiting gastrin-stimulated gastric acid secretion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA380Hu01 Recombinant Vasoactive Intestinal Peptide (VIP) Positive Control; Immunogen; SDS-PAGE; WB.
SPA380Hu01 Synthetic Vasoactive Intestinal Peptide (VIP) Immunogen; Blocking Peptide.
CPA380Mi21 OVA Conjugated Vasoactive Intestinal Peptide (VIP) Immunogen; SDS-PAGE; WB.
Antibodies PAA380Hu01 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
MAA380Hu22 Monoclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
MAA380Hu21 Monoclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB
Assay Kits CEA380Hu ELISA Kit for Vasoactive Intestinal Peptide (VIP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA380Mu01 Recombinant Vasoactive Intestinal Peptide (VIP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA380Mu02 Recombinant Vasoactive Intestinal Peptide (VIP) Positive Control; Immunogen; SDS-PAGE; WB.
CPA380Mi21 OVA Conjugated Vasoactive Intestinal Peptide (VIP) Immunogen; SDS-PAGE; WB.
Antibodies PAA380Mu01 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
PAA380Mu02 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
Assay Kits CEA380Mu ELISA Kit for Vasoactive Intestinal Peptide (VIP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA380Ra01 Recombinant Vasoactive Intestinal Peptide (VIP) Positive Control; Immunogen; SDS-PAGE; WB.
CPA380Mi21 OVA Conjugated Vasoactive Intestinal Peptide (VIP) Immunogen; SDS-PAGE; WB.
Antibodies PAA380Ra01 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
MAA380Ra21 Monoclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
Assay Kits CEA380Ra ELISA Kit for Vasoactive Intestinal Peptide (VIP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA380Gu01 Recombinant Vasoactive Intestinal Peptide (VIP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA380Gu01 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
MAA380Gu21 Monoclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
Assay Kits CEA380Gu ELISA Kit for Vasoactive Intestinal Peptide (VIP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA380Mi21 OVA Conjugated Vasoactive Intestinal Peptide (VIP) Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Vasoactive Intestinal Peptide (VIP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide (VIP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide (VIP) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA380Bo01 Recombinant Vasoactive Intestinal Peptide (VIP) Positive Control; Immunogen; SDS-PAGE; WB.
CPA380Mi21 OVA Conjugated Vasoactive Intestinal Peptide (VIP) Immunogen; SDS-PAGE; WB.
Antibodies PAA380Bo01 Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) WB; IHC; ICC; IP.
Assay Kits CEA380Bo ELISA Kit for Vasoactive Intestinal Peptide (VIP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA380Mi21 OVA Conjugated Vasoactive Intestinal Peptide (VIP) Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Vasoactive Intestinal Peptide (VIP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide (VIP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide (VIP) ELISA Kit Customized Service Offer
  1. "Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27."Nature 304:547-549(1983) [PubMed] [Europe PMC] [Abstract]
  2. "Structure of the human vasoactive intestinal polypeptide gene."DNA 4:293-300(1985) [PubMed] [Europe PMC] [Abstract]
  3. "Vasoactive intestinal peptide: expression of the prohormone in bacterial cells."Peptides 6 Suppl. 1:95-102(1985) [PubMed] [Europe PMC] [Abstract]
  4. "Structure and expression of the gene encoding the vasoactive intestinal peptide precursor."Proc. Natl. Acad. Sci. U.S.A. 84:605-609(1987) [PubMed] [Europe PMC] [Abstract]
  5. "Complete nucleotide sequence of human vasoactive intestinal peptide/PHM-27 gene and its inducible promoter."Ann. N. Y. Acad. Sci. 527:87-102(1988) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Structure and expression of the vasoactive intestinal peptide (VIP) gene in a human tumor."Peptides 7:1-6(1986) [PubMed] [Europe PMC] [Abstract]
  9. "Diarrhoea in vipoma patients associated with cosecretion of a second active peptide (peptide histidine isoleucine) explained by single coding gene."Lancet 2:1163-1165(1983) [PubMed] [Europe PMC] [Abstract]
  10. "Vasoactive intestinal peptide gene: putative mechanism of information storage at the RNA level."J. Neurochem. 48:1136-1141(1987) [PubMed] [Europe PMC] [Abstract]
  11. "Isolation, characterization, and pharmacological actions of peptide histidine valine 42, a novel prepro-vasoactive intestinal peptide-derived peptide."J. Biol. Chem. 262:14010-14013(1987) [PubMed] [Europe PMC] [Abstract]
  12. "Isolation and characterization of peptides which act on rat platelets, from a pheochromocytoma."Biochem. Biophys. Res. Commun. 185:134-141(1992) [PubMed] [Europe PMC] [Abstract]
  13. "Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor."Biochem. Pharmacol. 67:1279-1284(2004) [PubMed] [Europe PMC] [Abstract]
  14. "Structural determination of the vasoactive intestinal peptide by two-dimensional H-NMR spectroscopy."Biopolymers 31:459-464(1991) [PubMed] [Europe PMC] [Abstract]