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Immunoglobulin superfamily, member 1 (IGSF1)

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INHBP; IGCD1; IGDC1; INHBP; PGSF2; p120; Immunoglobulin Superfamily Member 1; Immunoglobulin-like domain-containing protein 1; Pituitary gland-specific factor 2

Immunoglobulin superfamily, member 1 (IGSF1)
CCC A273
HGNC 5948
MGI 2147913
PubMed 12832474
RGD 631402
UniProt Q8N6C5
Wiki IGSF1

IGSF1 contained 12 Ig-like domains of the C2 (constant region type 2) type. In addition, IGSF1 has a signal sequence and a potential transmembrane domain. IGSF1 was expressed as a 4.7-kb mRNA in many of the tissues tested, with the highest expression in pancreas, testis, and fetal liver. Additional 2.8- and 5.5-kb transcripts were observed in heart and testis, respectively. The cDNAs encoded a predicted 1,327-amino acid protein that was designated 'immunoglobulin superfamily member-1' (IGSF1) because it contained 12 Ig-like domains of the C2 (constant region type 2) type. In addition, IGSF1 has a signal sequence and a potential transmembrane domain. Northern blot analysis revealed that IGSF1 was expressed as a 4.7-kb mRNA in many of the tissues tested, with the highest expression in pancreas, testis, and fetal liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA273Hu01 Recombinant Immunoglobulin superfamily, member 1 (IGSF1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA273Hu03 Recombinant Immunoglobulin superfamily, member 1 (IGSF1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA273Hu02 Recombinant Immunoglobulin superfamily, member 1 (IGSF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA273Hu01 Polyclonal Antibody to Immunoglobulin superfamily, member 1 (IGSF1) WB; IHC; ICC; IP.
MAA273Hu22 Monoclonal Antibody to Immunoglobulin superfamily, member 1 (IGSF1) WB; IHC; ICC; IP.
PAA273Hu02 Polyclonal Antibody to Immunoglobulin superfamily, member 1 (IGSF1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Immunoglobulin superfamily, member 1 (IGSF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Immunoglobulin superfamily, member 1 (IGSF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA273Mu01 Recombinant Immunoglobulin superfamily, member 1 (IGSF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA273Mu01 Polyclonal Antibody to Immunoglobulin superfamily, member 1 (IGSF1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Immunoglobulin superfamily, member 1 (IGSF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Immunoglobulin superfamily, member 1 (IGSF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA273Ra01 Recombinant Immunoglobulin superfamily, member 1 (IGSF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA273Ra01 Polyclonal Antibody to Immunoglobulin superfamily, member 1 (IGSF1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Immunoglobulin superfamily, member 1 (IGSF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Immunoglobulin superfamily, member 1 (IGSF1) ELISA Kit Customized Service Offer
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  2. "Cloning and expression of an immunoglobulin superfamily gene (IGSF1) in Xq25."Genomics 48:157-162(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Expression profile of active genes in the human pituitary gland."J. Mol. Endocrinol. 28:33-44(2002) [PubMed] [Europe PMC] [Abstract]
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  8. "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs."Genome Res. 12:1773-1784(2002) [PubMed] [Europe PMC] [Abstract]
  9. "Properties of inhibin binding to betaglycan, InhBP/p120 and the activin type II receptors."Mol. Cell. Endocrinol. 196:79-93(2002) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement." Nat. Genet. 44:1375-1381(2012) [PubMed] [Europe PMC] [Abstract]