Estrone Sulfate (E1S)

Estrone sulfate(E1S) is a sulfated estrone. It has been described as a prognosis indicator for prostate cancer. It is a component of Premarin. Estrone sulfate is present at high concentration in plasma. It is a major circulating plasma estrogen and has a long plasma half-life; the large contributions of estrone and estradiol to plasma E1S are more than sufficient to account for all the circulating plasma E1S. It has been described as a prognosis indicator for prostate cancer.It is a component of Premarin. E₁S is present at high concentration in plasma. Using average production rates, all plasma E₁S could be shown to be derived from plasma estrone and estradiol.E₁S is a major circulating plasma estrogen and has a long plasma half-life; (b) the large contributions of estrone and estradiol to plasma E₁S are more than sufficient to account for all the circulating plasma E₁S.