Interferon Gamma (IFNg)

[Edit]

IFN-G; IFG; IFI; INFr; IFN, Immune Interferon

Interferon Gamma (IFNg)

Interferon gamma (IFN-gama ) is a multifunctional protein first observed as an antiviral activity in cultures of Sindbis virus-infected leukocytes stimulated by PHA . Produced by T lymphocytes and natural killer (NK) cells, IFN-γ is now known to be both an inhibitor of viral replication and a regulator of numerous immunological functions.

IFN-γ influences the class of antibody produced by B cells, upregulates class I and II MHC complex antigens and increases. the efficiency of macrophage-mediated killing of intracellular parasites. Most of the activities attributed to IFN-γ are believed to be mediated by IFN-γ-induced proteins. The appearance of such proteins is a consequence of IFN-γ binding to a specific receptor that is distinct from the receptor for IFN-αandβ.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Hu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Hu61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Hu61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
APA049Hu01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Hu01 Polyclonal Antibody to Interferon Gamma (IFNg) FCM
MAA049Hu22 Monoclonal Antibody to Interferon Gamma (IFNg) WB
LAA049Hu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Hu81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
PAA049Hu06 Polyclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Hu26 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Hu72 Biotin-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Hu82 FITC-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Hu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB
Assay Kits SEA049Hu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Hu CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.
AEA049Hu ELISA Kit for Anti-Interferon Gamma Antibody (Anti-IFNg) Enzyme-linked immunosorbent assay for Antibody Detection.
HEA049Hu High Sensitive ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Mu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Mu61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Mu01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
APA049Mu61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Mu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB
LAA049Mu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Mu81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
PAA049Mu02 Polyclonal Antibody to Interferon Gamma (IFNg) WB
PAA049Mu06 Polyclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Mu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Mu26 Monoclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Mu22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Mu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Mu CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.
HEA049Mu High Sensitive ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
AEA049Mu ELISA Kit for Anti-Interferon Gamma Antibody (Anti-IFNg) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ra01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
RPA049Ra02 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Ra61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Ra61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
APA049Ra01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
EPA049Ra62 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Ra63 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ra01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC
LAA049Ra71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Ra81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
PAA049Ra02 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ra21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Ra06 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ra22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ra23 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Ra ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Ra CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Gu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Gu01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Gu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Gu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB
LAA049Gu91 HRP-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Gu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
Assay Kits SEA049Gu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Gu CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Rb01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
RPA049Rb02 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Rb61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Rb61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Rb52 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Rb51 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Rb22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Rb71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Rb81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Rb21 Monoclonal Antibody to Interferon Gamma (IFNg) WB
PAA049Rb56 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Rb72 Biotin-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
Assay Kits SEA049Rb ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Rb CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Si01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Si01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Si21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Si ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Si CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ca01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ca01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ca21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Ca ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Ca CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Po01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Po61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Po61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
APA049Po01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Po01 Polyclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Po21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Po06 Polyclonal Antibody to Interferon Gamma (IFNg) Testing in progress
Assay Kits SEA049Po ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Po CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Bo01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Bo61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Bo01 Polyclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Bo21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Bo ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Bo CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interferon Gamma (IFNg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interferon Gamma (IFNg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Gamma (IFNg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Gamma (IFNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Gamma (IFNg) ELISA Kit Customized Service Offer

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ov01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ov01 Polyclonal Antibody to Interferon Gamma (IFNg) WB
LAA049Ov71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Ov81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Ov21 Monoclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Ov22 Monoclonal Antibody to Interferon Gamma (IFNg) WB
Assay Kits SEA049Ov ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Eq01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAA049Eq21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Eq01 Polyclonal Antibody to Interferon Gamma (IFNg) Testing in progress.
Assay Kits SEA049Eq ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ga01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ga01 Polyclonal Antibody to Interferon Gamma (IFNg) WB
MAA049Ga22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Ga71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Ga81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Ga21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Ga72 Biotin-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
Assay Kits SEA049Ga ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Ga CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Fi01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Fi01 Polyclonal Antibody to Interferon Gamma (IFNg) Testing in progress
Assay Kits n/a CLIA Kit for Interferon Gamma (IFNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Gamma (IFNg) ELISA Kit Customized Service Offer
  1. "Structure of the human immune interferon gene."Nature 298:859-863(1982) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of human immune interferon cDNA in E. coli and monkey cells."Nature 295:503-508(1982) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and expression of a novel variant of human interferon-gamma cDNA."J. Biochem. 97:153-159(1985) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning and structure of the human immune interferon-gamma chromosomal gene."EMBO J. 1:953-958(1982) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells."Nucleic Acids Res. 10:2487-2501(1982) [PubMed] [Europe PMC] [Abstract]
  6. "Human protein factory for converting the transcriptome into an in vitro-expressed proteome." Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation."J. Biol. Chem. 259:6790-6797(1984) [PubMed] [Europe PMC] [Abstract]
  9. "Structural characterization of human interferon gamma. Heterogeneity of the carboxyl terminus."Eur. J. Biochem. 166:145-149(1987) [PubMed] [Europe PMC] [Abstract]
  10. "Studies on the sugar chains of interferon-gamma from human peripheral-blood lymphocytes."J. Biochem. 105:1034-1039(1989) [PubMed] [Europe PMC] [Abstract]
  11. "Three-dimensional structure of recombinant human interferon-gamma."Science 252:698-702(1991) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor."Nature 376:230-235(1995) [PubMed] [Europe PMC] [Abstract]
  13. "Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma."J. Mol. Biol. 299:169-179(2000) [PubMed] [Europe PMC] [Abstract]
  14. "Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex."Structure 8:927-936(2000) [PubMed] [Europe PMC] [Abstract]
  15. "1H, 13C, and 15N NMR backbone assignments and secondary structure of human interferon-gamma."Biochemistry 31:8180-8190(1992) [PubMed] [Europe PMC] [Abstract]
  16. "Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population."Br. J. Haematol. 126:682-685(2004) [PubMed] [Europe PMC] [Abstract]