CLIA Kit for Interleukin 6 (IL6)

MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor

Specificity

This assay has high sensitivity and excellent specificity for detection of Interleukin 6 (IL6).
No significant cross-reactivity or interference between Interleukin 6 (IL6) and analogues was observed.

Recovery

Matrices listed below were spiked with certain level of recombinant Interleukin 6 (IL6) and the recovery rates were calculated by comparing the measured value to the expected amount of Interleukin 6 (IL6) in samples.

Matrix Recovery range (%) Average(%)
serum(n=5) 87-94 91
EDTA plasma(n=5) 80-94 80
heparin plasma(n=5) 80-92 87

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Interleukin 6 (IL6) were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Interleukin 6 (IL6) were tested on 3 different plates, 8 replicates in each plate.
CV(%) = SD/meanX100
Intra-Assay: CV<10%
Inter-Assay: CV<12%

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Interleukin 6 (IL6) and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample 1:2 1:4 1:8 1:16
serum(n=5) 90-101% 93-102% 85-93% 98-105%
EDTA plasma(n=5) 93-101% 82-101% 95-104% 78-91%
heparin plasma(n=5) 78-104% 83-102% 79-101% 86-101%

Stability

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Reagents and materials provided

Reagents Quantity Reagents Quantity
Pre-coated, ready to use 96-well strip plate 1 Plate sealer for 96 wells 4
Standard 2 Standard Diluent 1×20mL
Detection Reagent A 1×120µL Assay Diluent A 1×12mL
Detection Reagent B 1×120µL Assay Diluent B 1×12mL
Substrate A 1×10mL Substrate B 1×2mL
Wash Buffer (30 × concentrate) 1×20mL Instruction manual 1

Assay procedure summary

1. Prepare all reagents, samples and standards;
2. Add 100µL standard or sample to each well. Incubate 1 hours at 37°C;
3. Aspirate and add 100µL prepared Detection Reagent A. Incubate 1 hour at 37°C;
4. Aspirate and wash 3 times;
5. Add 100µL prepared Detection Reagent B. Incubate 30 minutes at 37°C;
6. Aspirate and wash 5 times;
7. Add 100µL Substrate Solution. Incubate 10 minutes at 37°C;
8. Read RLU value immediately.

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Saudi Journal of Gastroenterology Deoxyschizandrin suppresses dss-induced ulcerative colitis in mice. pubmed:27976641
Parasites & Vectors Vaccination of rabbits with immunodominant antigens from Sarcoptes scabiei induced highlevels of humoral responses and pro-inflammatory cytokines but confers limited protection. pubmed:27502394
Oncotarget Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation andapoptosis in diabetic cardiomyopathy. pubmed:27027354
Journal of Virology Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. pubmed:
Life Sciences Bone fracture healing is delayed in splenectomic rats pubmed:27956350
Food Funct. Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through the MAPK and NF-κB pathways. pubmed:28256654
Cell Death Dis. Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy pubmed:28333148
Biomedicine & pharmacotherapy= Biomedecine & pharmacotherapie Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion pubmed:28273631
Procalcitonin und proinflammatorische Zytokine in der bronchoalveolären Lavage beim lungenkranken Pferd unter inhalativer Glukokortikoidtherapie FUDISS_thesis_000000103830
International Journal of Stem Cell Research and Transplantation Protective Role of Bone Marrow Derived Mesenchymal Stem Cells-Conditioned Medium in the Infarcted Myocardium: The Potential Role of Selected Cytokines IJST-2328-3548-04-803
Kidney Research and Clinical Practice The role of local IL6/JAK2/STAT3 signaling in high glucose–induced podocyte hypertrophy S2211913216300912
Домашня сторінка ВПЛИВ КРОВОВТРАТИ НА ДИНАМІКУ ВМІСТУ ЦИТОКІНІВ СИРОВАТКИ КРОВІ В ПЕРІОД ГОСТРОЇ РЕАКЦІЇ НА КРАНІОСКЕЛЕТНУ ТРАВМУ 83646
Journal of Vascular Research Transplantation of Autologous Bone Marrow Mononuclear Cells Regulates Inflammation in aRabbit Model of Carotid Artery Atherosclerosis. pubmed:27788500
Neural regeneration research Breviscapine reduces neuronal injury caused by traumatic brain injury insult: partly associated with suppression of interleukin-6 expression pubmed:28250753
The Royal Society of Chemistry The positive role of macrophage secretion stimulated by BCP ceramic in the ceramic-induced osteogenic differentiation of pre-osteoblasts via Smad-related signaling pathways c6ra23362g
Journal of Agricultural and Food Chemistry Effect of boron on thymic cytokine expression, hormone secretion, antioxidant functions, cell proliferation, and apoptosis potential via the ERK1/2 signaling pathway pubmed:29032684
Heart and Vessels Interleukin-6 downregulated vascular smooth muscle cell contractile proteins via ATG4B-mediated autophagy in thoracic aortic dissection pubmed:28965202
PHYSIOLOGICAL RESEARCH Selective Inhibition of NF-κB and Surfactant Therapy in Experimental Meconium-Induced Lung Injury pubmed:28937237
Iranian Journal of Basic Medical Sciences Naringin attenuates diabetic retinopathy by inhibiting inflammation, oxidative stress and NF-κB activation in vivo and in vitro pubmed:28852447
Journal of Cellular Physiology Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Models pubmed:27739057
Oral Diseases Glucosamine oral administration as an adjunct to hyaluronic acid injection in treating temporomandibular joint osteoarthritis pubmed:28862770
Research in Veterinary Science The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs pubmed:28549299
Food & Function Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264. 7 macrophages through the MAPK and NF-κB … DOI:10.1039/C6FO01873D
Brain, Behavior, and Immunity The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in mice pubmed:28483659
cellular physiology and biochemistry Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β … pubmed:29040978
Food & Function Sea cucumber saponins liposomes ameliorate obesity-induced inflammation and insulin resistance in high-fat diet-fed mice pubmed:29292463
Microbial Immunology Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota pubmed:28713364
Archives of Oral Biology The effect of restorative materials on cytokines in gingival crevicular fluid pubmed:28992599
Journal of Microbiology, Immunology and Infection Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients pubmed:28655573
Scientific Reports A Systems Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Xipayi KuiJie’an enema for Treatment of Ulcerative colitis doi:10.1038/s41598-017-01335-w
PLoS One Relationship between microRNA-146a expression and plasma renalase levels in hemodialyzed patients pubmed:28614373
Chinese Journal of comparative medicine (中国比较医学杂志) 富氢液通过P13K通路减轻大鼠脑缺血再灌注损伤 doi:10u3969.j.issn.1671-7856
Oncotarget. Tumor-associated macrophages promote tumor metastasis via the TGF-β/SOX9 axis in non-small cell lung cancer pubmed:29245941
Giessener Elektronische Bibliothek Cytokines and immunoglobulin genetics in neonatal calf diarrhea 14.07.2017
University of Kassel Candidates present views Avion 1987-03-25
Oxidative Medicine and Cellular Longevity Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects pubmed:28798861
Nutrition Administration of probiotic mixture DM#1 ameliorated 5-fluorouracil-induced intestinal mucositis and dysbiosis in rats pubmed:27427511
Journal of Dairy Science Milk and serum IL-4, IL-6, IL-10, and amyloid A concentrations in cows with subclinical mastitis caused by coagulase-negative staphylococci pubmed:28964518
Current Eye Research Inhibition of Fusarium solani Infection in Murine Keratocytes by Lactobacillus salivarius ssp. salivarius JCM1231 Culture Filtrate In Vitro pubmed:28636459
Oxidative Medicine and Cellular Longevity Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophils pubmed:29081886
International Journal of Biological Sciences Chronic Osteomyelitis Increases the Incidence of Type 2 Diabetes in Humans and Mice pubmed:29104510
Oncology Letters Tanshinone II is a potent candidate for treatment of lipopolysaccharide-induced acute lung injury in rat model 10.3892/ol.2017.7581
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitis pubmed:29207044
Cellular Physiology and Biochemistry Dexmedetomidine Alleviates HyperoxiaInduced Acute Lung Injury via Inhibiting NLRP3 Inflammasome Activation pubmed:28873369
Acta Paediatrica Serum complement factor 5a levels are associated with nonalcoholic fatty liver disease in obese children DOI: 10.1111/apa.14106
Molecular Medicine Reports Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury 10.3892/mmr.2017.6837
International Journal of Clinical and Experimental Pathology Bone marrow-derived mesenchymal stem cells alleviates renal injury in severe acute pancreatitis via RhoA/Rho kinase ISSN:1936-2625
Tropical Journal of Pharmaceutical Research Protective effect of salvianolic acid B against intestinal ischemia reperfusion-induced injury in a rat model 10.4314/tjpr.v16i10.17
Pharmacology Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats pubmed:28637971
Metabolic Brain Disease Coenzyme Q10 and niacin mitigate streptozotocin-induced diabetic encephalopathy in a rat model pubmed:28560538
Biological Rhythm Research Alteration in some pro and anti-inflammatory cytokines associated with complete and incomplete gestation cycle of cows 10.1080/09291016.2017.1319636
Poultry Science The effect of DL-, L-isomers and DL-hydroxy analog administered at 2 levels as dietary sources of methionine on the metabolic and antioxidant parameters and growth performance of turkeys 10.3382/ps/pex099
Oncotarget The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis. pubmed:29029533
Oncotarget Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response. pubmed:28489606
International Journal of Cuban Health & Medicine Anemia and Iron Deficiency Related to Inflammation, Helicobacter pylori Infection and Adiposity in Reproductive-age Cuban Women 10.1590/MEDICC.2017.1902030004 
Oncotarget Global gene expression profile of cerebral ischemia-reperfusion injury in rat MCAO model pubmed:29088811
Oncotarget Neuroprotection of Botch in experimental intracerebral hemorrhage in rats. pubmed:29221132
Medycyna Pracy Wpływ pola magnetycznego niskiej częstotliwości stosowanego w magnetoterapii na zawartość interleukiny 6 (il-6) w sercu i mózgu szczura 10.13075/mp.5893.00354
Nature Medicine An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. pubmed:29227475
PLoS One Protective effect of aplysin on liver tissue and the gut microbiota in alcohol-fed rats pubmed:28622357
25 Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer. pubmed:29191973
Autonomic Neuroscience Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease. pubmed:29305058
Biological Rhythm Research A study of altered cytokine rhythms associated with successful implantation in cows 10.1080/09291016.2017.1361159
Inflammation Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20. pubmed:28744711
Biomedical and Environmental Sciences Grape Seed Procyanidin Extract Reduces Arsenic-Induced Renal Inflammatory Injury in Male Mice. pubmed:28756814
Arthritis Research and Therapy Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis. pubmed:29191221
Journal of contemporary medical sciences Attenuation of acute systemic inflammatory response after valve surgery ISSN: 1556-4002
Acta Pharmacologica Sinica Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ. pubmed:28649126
Toxicology Biological effects of adipocytes in sulfur mustard induced toxicity pubmed:29129815
Molecular Medicine Reports Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway pubmed:28944825
Veterinary microbiology Secondary Haemophilus parasuis infection enhances highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection-mediated inflammatory responses. pubmed:28532803
Frontiers in Molecular Neuroscience Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. pubmed:28959186
Chronic Respiratory Disease Inflammatory biomarkers and radiologic measurements in never-smokers with COPD: A cross-sectional study from the CODA cohort. pubmed:29117798
In Vivo Study on the Hindrance Activity of Cinnamon Extract Against Aspergillus niger in Mice ISSN: 0974-4290
Nature Medicine The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis Pubmed:29291351
Clinical Cancer Research Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration Pubmed:30012567
Clinical Cancer Research Reciprocal network between cancer stem-like cells and macrophages facilitates the progression and androgen deprivation therapy resistance of prostate cancer Pubmed:29691294
Journal of Controlled Release Nose-to-brain delivery of insulin enhanced by a nanogel carrier Pubmed:29196041
Anesthesiology Vasculotide, an angiopoietin-1 mimetic, restores microcirculatory perfusion and microvascular leakage and decreases fluid resuscitation requirements in … Pubmed:28968277
Cellular Physiology and Biochemistry Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory … Pubmed:29672286
International Journal of Obesity Leptin alleviates intestinal mucosal barrier injury and inflammation in obese mice with acute pancreatitis Pubmed:29934609
Molecular Nutrition & Food Research The Protective Activities of Dietary Sea Cucumber Cerebrosides Against Atherosclerosis Through Regulating Inflammation and Cholesterol Metabolism in Male Mice Pubmed:29883529
Environmental Pollution Exposure to environmental level phenanthrene induces a NASH-like phenotype in new born rat Pubmed:29656250
Neuropharmacology Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway Pubmed:29518397
American Journal of Physiology-Lung Cellular and Molecular Physiology Maternal PUFA omega-3 supplementation prevents hyperoxia-induced pulmonary hypertension in the offspring Pubmed:29597832
Journal of Clinical Periodontology  Peroxisome proliferator‐activated receptor γ plays dual roles on experimental periodontitis in rats Pubmed:29574908
International Journal of Molecular Sciences Screening of circular RNAs and validation of circANKRD36 associated with inflammation in patients with type 2 diabetes mellitus Pubmed:30066828
British journal of nutrition Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1, 2-dimethylhydrazine-induced rat colorectal … Pubmed:29947321
Frontiers in Neurology Ursolic Acid Ameliorates Inflammation in Cerebral Ischemia and Reperfusion Injury Possibly via High Mobility Group Box 1/Toll-Like Receptor 4/NFκB … Pubmed:29867706
Journal of Functional Foods Hepatoprotective effect of flavonoid-enriched fraction from Cyclocarya paliurus leaves on LPS/D-GalN-induced acute liver failure 10.1016:j.jff.2018.07.031
Molecular Brain Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats Pubmed:29439730
Inflammopharmacology Protective effect of isoliquiritigenin against cerebral injury in septic mice via attenuation of NF-κB Pubmed:29943151
Inflammopharmacology Polar extract of protects cartilage homeostasis: possible mechanism of action Pubmed:29313174
Food & Function Asiatic acid suppresses neuroinflammation in BV2 microglia via modulation of the Sirt1/NF-κB signaling pathway Pubmed:29354820
Life Sciences Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation Pubmed:29499280
Life Sciences Dexmedetomidine attenuates renal fibrosis via α2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusion Pubmed:29729264
Life Sciences Modified porcine surfactant enriched by recombinant human superoxide dismutase for experimental meconium aspiration syndrome Pubmed:29684443
Brain Research Intra-arterial human urinary kallidinogenase alleviates brain injury in rats with permanent middle cerebral artery occlusion through PI3K/AKT/FoxO1 signaling pathway Pubmed:29510144
International Immunopharmacology Switched memory B cells promote alveolar bone damage during periodontitis: An adoptive transfer experiment Pubmed:30015235
Free Radical Research Lycium barbarum polysaccharide protects against LPS-induced ARDS by inhibiting apoptosis, oxidative stress, and inflammation in pulmonary endothelial cells Pubmed:29502482
Oncology Reports Silencing of Girdin suppresses the malignant behavior of colorectal carcinoma cells Pubmed:29989653
Bioscience Reports Decreased miR-128 expression alleviated the progression of Rheumatoid arthritis by up-regulating the expression of TNFAIP3 Pubmed:29853534
International Journal of Molecular Medicine Aspirin modulates the inflammatory response in a thrombus‑stimulated LMVEC model Pubmed:29568915
Neurochemical Research E3 Ubiquitin Ligase c-cbl Inhibits Microglia Activation After Chronic Constriction Injury Pubmed:29934689
PLoS One Chitosan oligosaccharide ameliorates acute lung injury induced by blast injury through the DDAH1/ADMA pathway Pubmed:29415054
Journal of Dairy Science Relationship between body condition score and plasma adipokines in early-lactating Holstein dairy cows Pubmed:30007810
Biochemical and Biophysical Research Communications PPARγ alleviated hepatocyte steatosis through reducing SOCS3 by inhibiting JAK2/STAT3 pathway Pubmed:29550470
Biochemical and Biophysical Research Communications Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae) Pubmed:29626477
International Immunopharmacology  Tn (-acetyl-d-galactosamine--serine/threonine) immunization protects against hyperoxia-induced lung injury in adult mice through inhibition of the nuclear factor … Pubmed:29669308
Experimental biology and medicine (Maywood) Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse model Pubmed:29984607
Probiotics Antimicrob Proteins Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a … Pubmed:29305686
International Journal of Endocrinology Uncoupling Protein 2 and Peroxisome Proliferator-Activated Receptor γ Gene Polymorphisms in Association with Diabetes Susceptibility in Chinese Han Population … Pubmed:29849618
Microbial Pathogenesis Pathogen-dependent modulation of milk neutrophils competence, plasma inflammatory cytokines and milk quality during intramammary infection of Sahiwal (Bos … Pubmed:29787791
Archives of Virology MAVS induces a host cell defense to inhibit CSFV infection Pubmed:29556776
Food & Nutrition Research Immunomodulatory activity of Lactobacillus plantarum KLDS1. 0318 in cyclophosphamide-treated mice Pubmed:30026678
BMC Veterinary Research Inflammatory pattern of the infrapatellar fat pad in dogs with canine cruciate ligament disease Pubmed:29769086
Molecular Medicine Reports Protective effects of N (2)‑L‑alanyl‑L‑glutamine mediated by the JAK2/STAT3 signaling pathway on myocardial ischemia reperfusion Pubmed:29393473
Molecular Medicine Reports  Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats Pubmed:29956781
Molecular Medicine Reports Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway Pubmed:29620209
Medical Science Monitor Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4) … Pubmed:29804125
Medical Science Monitor Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats Pubmed:29290631
Medical Science Monitor Sulforaphane, a Natural Isothiocyanate Compound, Improves Cardiac Function and Remodeling by Inhibiting Oxidative Stress and Inflammation in a Rabbit … Pubmed:29527002
Experimental Lung Research Anti-IL-8 antibody potentiates the effect of exogenous surfactant in respiratory failure caused by meconium aspiration Pubmed:29324051
International Urology and Nephrology Mesenchymal stem cells alleviate acute kidney injury by down-regulating C5a/C5aR pathway activation Pubmed:29594894
Oncology Letters Hydrogen‑rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus‑activated kinase 2/signal transducer and activator of … Pubmed:29928398
Research in Veterinary Science Milk fever in dairy cows is preceded by activation of innate immunity and alterations in carbohydrate metabolism prior to disease occurrence Pubmed:29277015
Journal of Maternal-Fetal & Neonatal Medicine Amniotic fluid HIF1α and exosomal HIF1α in cervical insufficiency patients with physical examination-indicated cerclage Pubmed:29357727
Pakistan Veterinary Journal Comparison of Plasma Interleukin-6 and Interleukin-10 Concentrations between Female Dogs with Mammary Gland Tumours and Healthy 17-377.pdf
International Journal of Environmental Studies  Effectiveness of steamed and cooked broccoli to attenuate bone marrow injury and suppressed haemopoiesis in male rats exposed to petrol vapours 10.1080:00207233.2018.1502956
Tropical Animal Health andProduction Effect of reproductive disorders on productivity and reproductive efficiency of dromedary she-camels in relation to cytokine concentration Pubmed:29423707
International Journal of Clinical and Experimental Medicine BoNT-A attenuated pain of endometriosis by inhibiting microglia activation files:ijcem0055240.pdf
Journal of Veterinary Science Rifaximin anti‐inflammatory activity on bovine endometrium primary cell cultures: a preliminary study Pubmed:29984902
A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice :
Biotechnic & Histochemistry Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats Pubmed: 30234391
Platelets Effects of different doses of ticagrelor on platelet aggregation and endothelial function in diabetic patients with stable coronary artery disease Pubmed: 30252571
American Journal of Translational Research Human mesenchymal stem cells attenuate hyperoxia-induced lung injury through inhibition of the renin-angiotensin system in newborn rats Pubmed: 30210699
Life Sciences Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS partially via the Sirt3/AMPK signaling axis Pubmed: 30171880
Communications Biology Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia
International Journal of Clinical and Experimental Pathology Can the indicators of chronic ethanol consumption be minimized by a continuous flaxseed intake? Pubmed: 30338600
Food Science and Technology Research Combinational Effect of Pine Needle Polysaccharide and Kudzu Flavonoids on Cell Differentiation and Fat Metabolism in 3T3-L1 Cells Doi: 10.3136/fstr.24.903
Neurobiology of Disease Glucagon-like peptide-2 reduces the obesity-associated inflammation in the brain Pubmed: 30347266
Journal of Dairy Science Metabolism and immune status during transition period influences the lactation performance in Zebu (Bos indicus () cows Pubmed: 17430930
International Immunopharmacology Naringin protects against perfluorooctane sulfonate-induced liver injury by modulating NRF2 and NF-κB in mice Pubmed: 30316072
Immunology DNA prime‐protein boost vaccine encoding HLA‐A2,‐A24 and‐DR 1 restricted epitopes of Ca NA 2 against visceral leishmaniasis
Journal of Pharmacological Sciences Improved endogenous epoxyeicosatrienoic acid production mends heart function via increased PGC 1α-mitochondrial functions in metabolic syndrome Pubmed: 30342783
Metabolic Brain Disease Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms Pubmed: 30456649
Emerging Microbes & Infections Immunogenicity and protective efficacy against Treponema pallidum in New Zealand rabbits immunized with plasmid DNA encoding flagellin Pubmed: 30405111
Research in Veterinary Science Levels of selected cytokines and acute–phase proteins in the serum of dairy cows with cystic ovarian disease and those in follicular and luteal phases of normal … Pubmed: 30580231
Annals of Animal Science Redox and immunological status of turkeys fed diets with different levels and sources of copper
Biomedicine & Pharmacotherapy Corn silk (Zea mays L.), a source of natural antioxidants with α-amylase, α-glucosidase, advanced glycation and diabetic nephropathy inhibitory activities Pubmed: 30530231
Experimental Neurology Significant changes in circular RNA in the mouse cerebral cortex around an injury site after traumatic brain injury Pubmed: 30529438
International Journal of Clinical and Experimental Medicine Effects of fecal microbiota transplantation and joint application of probiotics on rats with alcoholic liver disease
Journal of Equine Veterinary Science Differences In Blood Parameters Associated To Stress Response Between Chilean Rodeo Horses And Chilean Urban Working Horses Doi: 10.1016/j.jevs.2018.12.005
BBA- Molecular Basis of Disease Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic … Pubmed: 30553018
Journal of Veterinary Research Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle
International Journal of Chronic Obstructive Pulmonary Disease Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD Pubmed: 30655663
Neurochemical Research Sinomenine Attenuates Traumatic Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation via Nrf2 Pathway Pubmed: 30603983
EXPERIMENTAL ANIMALS Protective effects of sulforaphane on diabetic retinopathy: activation of the Nrf2 pathway and inhibition of NLRP3 inflammasome formation Pubmed: 30606939
ACS Applied Materials & Interfaces Rebuilding post-infarcted cardiac functions by injecting TIIA@ PDA NPs-crosslinked ROS sensitive hydrogels Pubmed: 30592403
Chinese Journal of Integrative Medicine Electroacupuncture Delays Cartilage Degeneration by Modulating Nuclear Factor-κB Signaling Pathway Pubmed: 30656598
The American Journal of Sports Medicine Short-term Changes After Corticosteroid Injections Into the Normal Tendons of Rabbits: A Controlled Randomized Study Pubmed: 30640506
Journal of Hepatology Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: reversal by anti-tnfa treatment Pubmed: 30654069
Inflammopharmacology Chandrasekaran Chinampudur Velusami, Edwin Jothie Richard &
Journal Of Clinical Investigation Long non-coding RNA mitigates atherosclerosis by regulating the actin-binding protein NEXN Pubmed: 30589415
Inflammation Honokiol Attenuates Sepsis-Associated Acute Kidney Injury the Inhibition of Oxidative Stress and Inflammation Pubmed: 30680694
Toxicology Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: a role in Kupffer cell activation Pubmed: 30685357
Acta Biochimica et Biophysica Sinica Adiponectin attenuates lipopolysaccharide-induced cell injury of H9c2 cells by regulating AMPK pathway Pubmed: 30668810
Journal of Neuroinflammation Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer's disease Pubmed: 30777084
Journal of Functional Foods Transcriptome profiling reveals the anti-diabetic molecular mechanism of Cyclocarya paliurus polysaccharides: Anti-diabetic molecular mechanism of Cyclocarya?… Doi: 10.1016/j.jff.2018.12.039
Journal of Surgical Research Unfractionated Heparin Alleviates Sepsis-Induced Acute Lung Injury by Protecting Tight Junctions Pubmed: 30771687
Phytotherapy Research Synergistic enhancement and hepatoprotective effect of combination of total phenolic extracts of L. and methotrexate for treatment of rheumatoid?… Pubmed: 30729592
Life Sciences Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease
Biological & Pharmaceutical Bulletin Astragaloside IV regulates the PI3K/Akt/HO-1 signaling pathway and inhibits H9c2 cardiomyocyte injury induced by hypoxia-reoxygenation Pubmed: 30867343
Biomedicine & Pharmacotherapy Three types of gut bacteria collaborating to improve Kui Jie'an enema treat DSS-induced colitis in mice Pubmed: 30870717
International Journal of Immunopathology and Pharmacology Effect of voluntary running on expression of myokines in brains of rats with depression Pubmed: 30834799
Royal Society Open Science Metabolomics analysis of baicalin on ovalbumin-sensitized allergic rhinitis rats
International Journal of Nanomedicine Improving the anti-keloid outcomes through liposomes loading paclitaxel–cholesterol complexes Pubmed: 30863067
Experimental Biology and Medicine Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signaling Pubmed: 30869553
BioMed Research International Effective Treatment of Bovine Mastitis with Intramammary Infusion of Angelica dahurica and Rheum officinale Extracts
BioMed Research International Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway
Journal of Pineal Research Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice Pubmed: 30929267
Experimental Lung Research Roles of citric acid in conjunction with saline nebulization in experimental tracheostomy in guinea pigs Pubmed: 30973274
PLoS One Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis Pubmed: 30939166
Toxicon The wound healing potential of a pro-angiogenic peptide purified from Indian Russell's viper (Daboia russelii) venom Pubmed: 31054289
Journal of Cellular Physiology Knockdown of periostin attenuates 5/6 nephrectomy‐induced intrarenal renin–angiotensin system activation, fibrosis, and inflammation in rats
The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency
OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES Seluang Fish (Rasbora Spp.) Oil Decreases Inflammatory Cytokines Via Increasing Vitamin D Level in Systemic Lupus Erythematosus
J Recept Signal Transduct Res miR-21 promotes proliferation and inhibits apoptosis of hepatic stellate cells through targeting PTEN/PI3K/AKT pathway Pubmed: 31038023
Journal of Investigative Medicine Intraperitoneal administration of activin A promotes development of endometriotic lesions in a mouse model of endometriosis Pubmed: 31064924
Phytotherapy Research Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke‐induced airway inflammation Pubmed: 31209984
Ann Intensive Care Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study Pubmed: 31183575
Food & Function Synergistic effect of sea cucumber saponin and EPA-enriched phospholipids on insulin resistance in high-fat diet-induced obese mice Pubmed: 31199413
Food & Function Eicosapentaenoic acid in the form of phospholipid exerts superior anti-atherosclerosis effects than its triglyceride form in ApoE-/-mice
Frontiers in Immunology Expression and Purification of Hybrid LL-37Tα1 Peptide in Pichia pastoris and evaluation of their Immunomodulatory and anti-inflammatory activities by LPS …
Food & Function Network pharmacology oriented study reveals inflammatory state-dependent dietary supplement hepatotoxicity responses in normal and diseased rats Pubmed: 31140472
Journal of the Royal Army Medical Corps CD28 deficiency attenuates primary blast-induced renal injury in mice via the PI3K/Akt signalling pathway Pubmed: 31129646
Metallomics Lanthanum chloride induces neuron damage by activating the nuclear factor-kappa B signaling pathway in activated microglia Pubmed: 31187842
Pinealektomize Edilmiş Septik Sıçanlarda TNF-α, IL-6, IL-10 ve IL-1β'nin Kan Düzeyleri ile Karaciğer ve Böbrekte Gen Ekspresyonu Seviyelerindeki … Doi: 10.5505/vtd.2019.32815
Biomaterials Magnetic-responsive and targeted cancer nanotheranostics by PA/MR bimodal imaging-guided photothermally triggered immunotherapy
Journal of Neurochemistry Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury Pubmed: 31314915
Archives of Dermatological Research STAT3 polymorphisms and IL-6 polymorphism are associated with the risk of basal cell carcinoma in patients from northern Poland Pubmed: 31342143
neuroscience letters Madecassoside ameliorates lipopolysaccharide-induced neurotoxicity in rats by activating the Nrf2-HO-1 pathway Pubmed: 31330225
Research in Veterinary Science Evaluation of infrared thermography compared to rectal temperature to identify illness in early postpartum dairy cows
Inflammopharmacology PD123319, angiotensin II type II receptor antagonist, inhibits oxidative stress and inflammation in 2, 4-dinitrobenzene sulfonic acid-induced colitis in rat and … Pubmed: 31321575
Health and Medicine Antiallergical Effect of New Combined Nazal Aerodisperse System in the Conditions of Experimental Allergic Rhinitis
Biomedicine & Pharmacotherapy MODULATION OF LIPOPOLYSACCHARIDE-INDUCED CYTOKINES RESPONSE IN MICE BY GRAVIOLA LEAF POWDER
Free Radical Biology and Medicine Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat Pubmed: 31255668
Parasite Immunology KLF4 upregulation is involved in alternative macrophage activation during secondary Echinococcus granulosus infection Pubmed: 31407814
Journal of Pediatric Surgery The effects of hydrogen-rich saline solution on intestinal anastomosis performed after intestinal ischemia reperfusion injury
Nutrients Cardioprotective Effect of a Virgin Olive Oil Enriched with Bioactive Compounds in Spontaneously Hypertensive Rats Pubmed: 31357464
Int Immunopharmacol Metallothionein-1 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cells Pubmed: 31465913
Animals Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training Pubmed: 31462005
Frontiers in Pharmacology Naoxintong Capsule Inhibits the Development of Cardiovascular Pathological Changes in Bama Minipig Through Improving Gut Microbiota Pubmed: 31632272
Scientific Reports Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus Pubmed: 31578381
Human & Experimental Toxicology The effects of L-NAME on DU145 human prostate cancer cell line: a cytotoxicity-based study Pubmed: 31610702
Journal of Medicinal Food Polysaccharide from the Seeds of Plantago asiatica L. Protect Against Lipopolysaccharide-Induced Liver Injury Pubmed: 31560611
Scientific Reports The N-Acetyl Phenylalanine Glucosamine Derivative Attenuates the Inflammatory/Catabolic Environment in a Chondrocyte-Synoviocyte Co-Culture System Pubmed: 31537813
International Journal of Molecular Medicine Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway Pubmed: 31545485
Pakistan Journal of Biological Sciences Research Article Potential Protective Role of Rutin and Alpha-lipoic Acid Against Cisplatin-induced Nephrotoxicity in Rats Pubmed: 31930824
INCREASED INTRA-ARTICULAR GRANZYME M TRIGGERS LOCAL PROINFLAMMATORY CYTOKINE RELEASE IN RHEUMATOID ARTHRITIS Pubmed: 31172927
Food & Function Collaborative Effects of Chlorogenic Acid and Caffeine on Lipid Metabolism via AMPKα-LXRα/SREBP-1c Pathway in High-Fat Diet-Induced Obese Mice Pubmed: 31670366
BMC Veterinary Research The immune response of young turkeys to haemorrhagic enteritis virus infection at different levels and sources of methionine in the diet Pubmed: 31675966
BMC Complementary and Alternative Medicine Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway Pubmed: 31747940
Bioscience Reports Salidroside mitigates skeletal muscle atrophy in rats with cigarette smoke-induced COPD by up-regulating myogenin and down-regulating myostatin expression Pubmed: 31702007
International Immunopharmacology Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury Pubmed: 31835081
Folia Morphologica Beneficial effects of voluntary over forced exercise on skeletal muscle structure and myokines expression Pubmed: 31802473
Journal of Hazardous Materials Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal mice Pubmed: 31796355
Journal of Controlled Release Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury Pubmed: 31783047
Journal of Cardiovascular Translational Research XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial Infarction Pubmed: 31768947
Journal of Food Science Effects of Total Flavonoids from Exocarpium Citri Grandis on Air Pollution Particle‐Induced Pulmonary Inflammation and Oxidative Stress in Mice Pubmed: 31762039
Journal of Photochemistry and Photobiology B Neuroprotective effect of Wogonin on Rat's brain exposed to gamma irradiation Pubmed: 31935591
international urology and nephrology The therapeutic effect of dendritic cells expressing indoleamine 2, 3-dioxygenase (IDO) on an IgA nephropathy mouse model Pubmed: 31894556
Archives of Biochemistry and Biophysics Syringin protects against colitis by ameliorating inflammation Pubmed: 31899146
Frontiers in Immunology The Increase in IL-1β in the Early Stage of Heatstroke Might Be Caused by Splenic Lymphocyte Pyroptosis Induced by mtROS-Mediated Activation of the … Pubmed: 31921131
Nutrients Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes Rats Pubmed: 31887996
Transboundary and Emerging Diseases Pathogenicity of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1–7–4 viruses) in China Pubmed: 32187856
GENES TO CELLS MiR‐29c‐3p inhibits microglial NLRP3 inflammasome activation by targeting NFAT5 in Parkinson's disease Pubmed: 32160394
research in veterinary science The association of circulating prepartum metabolites, minerals, cytokines and hormones with postpartum health status in dairy cattle Pubmed: 32172001
Nanomedicine The toxicity of alumina nanoparticles to immune system in mice Pubmed: 32162999
Endocrine Glucagon-like peptide-2 analog and inflammatory state in obese mice Pubmed: 32172484
Oxidative Medicine and Cellular Longevity Leukocyte Telomere Length Independently Predicts 3-Year Diabetes Risk in a Longitudinal Study of Chinese Population Pubmed: 32215181
Scientific Reports Corrosion Resistance of Graphene oxide/Silver Coatings on Ni–Ti alloy and Expression of IL-6 and IL-8 in Human Oral Fibroblasts Pubmed: 32094428
Biomed Pharmacother Suppression of Fpr2 expression protects against endotoxin-induced acute lung injury by interacting with Nrf2-regulated TAK1 activation Pubmed: 32106380
BRAIN BEHAVIOR AND IMMUNITY AVNP2 protects against cognitive impairments induced by C6 glioma by suppressing tumour associated inflammation in rats Pubmed: 32097763
Food & Function Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial Pubmed: 32044905
Braz J Med Biol Res Anti-placental growth factor antibody ameliorates hyperoxia-mediated impairment of lung development in neonatal rats Pubmed: 31994602
Antibiotics Effects of Early Intervention with Antibiotics and Maternal Fecal Microbiota on Transcriptomic Profiling Ileal Mucusa in Neonatal Pigs Pubmed: 31963653
Frontiers in Microbiology Topical Therapeutic Efficacy of Ebselen Against Multidrug-Resistant Staphylococcus aureus LT-1 Targeting Thioredoxin Reductase Pubmed: 32010088
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Nonsteroidal anti‐inflammatory drugs alleviate severity of post‐ERCP pancreatitis by inhibiting inflammation and reducing apoptosis Pubmed: 32064683
JOURNAL OF HAZARDOUS MATERIALS Silica nanoparticles induce JNK-mediated inflammation and myocardial contractile dysfunction Pubmed: 32036317
Biomed Research International Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB … Pubmed: 32071922
Physiol Res Effect of Different Dosages of Dexamethasone Therapy on Lung Function and Inflammation in an Early Phase of Acute Respiratory Distress Syndrome Model Pubmed: 31928043
Archives of Biochemistry and Biophysics Micro RNA 146a gene variant/TNF-α/IL-6/IL-1 β; A cross-link axis inbetween oxidative stress, endothelial dysfunction and neuro-inflammation in acute ischemic stroke … Pubmed: 31738890
Medical Science Monitor MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 … Pubmed: 31710596
Respiratory Research Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory … Pubmed: 31694668
Carbohydrate Polymers Two different fucosylated chondroitin sulfates: structural elucidation, stimulating hematopoiesis and immune-enhancing effects Pubmed: 31887892
Silkworm pupa oil attenuates acetaminophen‐induced acute liver injury by inhibiting oxidative stress‐mediated NF‐κB signaling Pubmed: 31993149
Irisin Improves Autophagy of Aged Hepatocytes via Increasing Telomerase Activity in Liver Injury Pubmed: 31976032
Food Science & Nutrition Anti‐inflammatory effect from extracts of Red Chinese cabbage and Aronia in LPS‐stimulated RAW 264.7 cells Pubmed: 32328255
Journal of Pharmacy and Pharmacology Tectorigenin inhibits inflammation and pulmonary fibrosis in allergic asthma model of ovalbumin‐sensitized guinea pigs Pubmed: 32314371
journal of dairy science Mitochondrial membrane protein mitofusin 2 as a potential therapeutic target for treating free fatty acid–induced hepatic inflammation in dairy cows during early … Pubmed: 32278565
Inflammation Cyanidin-3-O-Glucoside Attenuates Lipopolysaccharide-Induced Inflammation in Human Corneal Epithelial Cells by Inducing Let-7b-5p-Mediated HMGA2/PI3K/Akt … Pubmed: 32248330
Pharmazie Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB/IκB signaling pathway in rabbit ears Pubmed: 32213242
Stem Cells International Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2 … Pubmed: 32300366
Marine Drugs Tu-Teng-Cao Extract Alleviates Monosodium Urate-Induced Acute Gouty Arthritis in Rats by Inhibiting Uric Acid and Inflammation Pubmed: 23306170
Nanomaterials An OMV-Based Nanovaccine Confers Safety and Protection against Pathogenic Escherichia coli via Both Humoral and Predominantly Th1 Immune Responses in … Pubmed: 33233490
LIFE SCIENCES Intravitreal conbercept improves outcome of proliferative diabetic retinopathy through inhibiting inflammation and oxidative stress Pubmed: 33227274
BLOOD Halting the FGF/FGFR axis leads to anti-tumor activity in Waldenström's Macroglobulinemia by silencing MYD88. Pubmed: 33197938
Sci Rep NFKB1 gene rs28362491 ins/del variation is associated with higher susceptibility to myocardial infarction in a Chinese Han population Pubmed: 33177541
Exp Lung Res Ketogenic diet induces autophagy to alleviate bleomycin-induced pulmonary fibrosis in murine models Pubmed: 33121292
Cell Biochem Funct The role of Smad4 in the regulation of insulin resistance, inflammation and cell proliferation in HTR8‐Svneo cells Pubmed: 33079408
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Gastroprotective effect of Lycium barbarum polysaccharides and C-phyocyanin in rats with ethanol-induced gastric ulcer Pubmed: 33058973
Neuroscience A new therapeutic strategy targeting protein deacetylation for spinal cord injury Pubmed: 33039524
BIOMEDICINE & PHARMACOTHERAPY Chlorogenic acid prevents acute myocardial infarction in rats by reducing inflammatory damage and oxidative stress Pubmed: 33022535
INFLAMMATION GPR120 Ameliorates Apoptosis and Inhibits the Production of Inflammatory Cytokines in Renal Tubular Epithelial Cells Pubmed: 33009637
DRUG AND CHEMICAL TOXICOLOGY Toxicological impact of sodium benzoate on inflammatory cytokines, oxidative stress and biochemical markers in male Wistar rats Pubmed: 33003960
BMC Anesthesiology Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a … Pubmed: 32988385
Heliyon Effect of procyanidins on lipid metabolism and inflammation in rats exposed to alcohol and iron Pubmed: 32964156
Int J Neurosci Downregulation of ROCK2 attenuates alcohol-induced inflammation and oxidative stress in astrocytes Pubmed: 32942936
Autophagy LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection Pubmed: 32924761
Biomed Pharmacother Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis Pubmed: 32920515
J Cell Mol Med LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway Pubmed: 32881263
Nanotoxicology miR-205/IRAK2 signaling pathway is associated with urban airborne PM2.5-induced myocardial toxicity Pubmed: 32880512
Drug Design Development and Therapy Exosomes Derived from MicroRNA-146a-5p-Enriched Bone Marrow Mesenchymal Stem Cells Alleviate Intracerebral Hemorrhage by Inhibiting Neuronal … Pubmed: 32821084
THERIOGENOLOGY Porcine soluble CD83 alleviates LPS-induced abortion in mice by promoting Th2 cytokine production, Treg cell generation and trophoblast invasion Pubmed: 32810792
Theriogenology A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cows Pubmed: 32810791
Biochimie Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing Pubmed: 32800897
Peptides Liraglutide ameliorates lipotoxicity-induced inflammation through the mTORC1 signalling pathway Pubmed: 32771373
Journal of Natural Medicines Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation … Pubmed: 32761488
MOLECULAR AND CELLULAR BIOCHEMISTRY MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1 Pubmed: 32737769
Inflamm Res IL-33 deficiency protects mice from DSS-induced experimental colitis by suppressing ILC2 and Th17 cell responses Pubmed: 32728764
BRITISH JOURNAL OF PHARMACOLOGY A novel apoA‐I mimetic peptide suppresses atherosclerosis by promoting physiological HDL function in apoE−/− mice Pubmed: 32726461
Int Immunopharmacol BNIP3 deletion ameliorated enterovirus 71 infection-induced hand, foot and mouth disease via inhibiting apoptosis, autophagy, and inflammation in mice Pubmed: 32717566
Lab Invest Extracellular cold-inducible RNA-binding protein regulates neutrophil extracellular trap formation and tissue damage in acute pancreatitis Pubmed: 32709888
Parasites & Vectors Fasciola gigantica excretory-secretory products (FgESPs) modulate the differentiation and immune functions of buffalo dendritic cells through a mechanism … Pubmed: 32680553
Cell Cycle SIRT1 relieves Necrotizing Enterocolitis through inactivation of Hypoxia-inducible factor (HIF)-1a Pubmed: 32657204
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Highly Branched RG-I Domain Enrichment are Indispensable for Pectin Mitigating Against High-Fat Diet-Induced Obesity Pubmed: 32633953
journal of clinical laboratory analysis has_circ_CCNB1 and has_circ_0009024 function as potential biomarkers for the diagnosis of type 2 diabetes mellitus Pubmed: 32633001
Scientific Reports Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats Pubmed: 32616735
Mediators Inflamm Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB … Pubmed: 32587471
BIOLOGICAL TRACE ELEMENT RESEARCH Association Between Serum Selenium Level and Subclinical Mastitis in Dairy Cattle Pubmed: 32583225
Molecular Medicine Reports Aquaporin‑4 deletion ameliorates enterovirus 71 infection in mice Pubmed: 32582978
Frontiers in Bioengineering and Biotechnology In vitro Impact of Yeast Expressed Hybrid Peptide CATH-2TP5 as a Prophylactic Measure Toward Sepsis and Inflammation Pubmed: 32582649
Prostate The effect of pirfenidone on rat chronic prostatitis/chronic pelvic pain syndrome and its mechanisms Pubmed: 32569423
BIOTECHNOLOGY LETTERS Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway Pubmed: 32567013
INTERNATIONAL IMMUNOPHARMACOLOGY A potential drug combination of omeprazole and patchouli alcohol significantly normalizes oxidative stress and inflammatory responses against gastric ulcer in ethanol … Pubmed: 32559721
OBESITY SURGERY The Protective Effects of Butorphanol on Pulmonary Function of Patients with Obesity Undergoing Laparoscopic Bariatric Surgery: a Double-Blind Randomized … Pubmed: 32535786
Journal of Neuroinflammation CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats Pubmed: 32532282
SHOCK Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue Pubmed: 32530844
Frontiers in Pharmacology Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-κB … Pubmed: 32528295
Neurotoxicology Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice Pubmed: 32522471
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE The microvesicle/CD36 complex triggers a prothrombotic phenotype in patients with non‐valvular atrial fibrillation Pubmed: 32510852
BMC Complement Med Ther Network pharmacology to dissect the mechanisms of Yinlai Decoction for pneumonia Pubmed: 32493296
molecular and cellular endocrinology Andrographolide modulates HNF4α activity imparting on hepatic metabolism Pubmed: 32422400
Int J Mol Sci Effects of PDE3 Inhibitor Olprinone on the Respiratory Parameters, Inflammation, and Apoptosis in an Experimental Model of Acute Respiratory Distress Syndrome Pubmed: 32403267
Int Immunopharmacol Celastrol attenuates collagen-induced arthritis via inhibiting oxidative stress in rats Pubmed: 32402948
pharmacological research 18β-Glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism Pubmed: 32353589
american journal of physiology-lung cellular and molecular physiology Extracellular Vesicles in Lung Health, Disease, and Therapy: Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung … Pubmed: 32073873
ACS Chemical Neuroscience α-Synuclein Exhibits Differential Membrane Perturbation, Nucleation, and TLR2 Binding through Its Secondary Structure Pubmed: 33196165
Journal of Diabetes Research Regulation and Mechanism of miR-518d through the PPARα-Mediated NF-κB Pathway in the Development of Gestational Diabetes Mellitus Pubmed: 33123597
International Immunopharmacology Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway Pubmed: 33182056
European Review for Medical and Pharmacological Sciences Neuroprotective effect of CTRP3 overexpression against sevoflurane anesthesia-induced cognitive dysfunction in aged rats through activating AMPK/SIRT1 and … Pubmed: 32432773
κ‑opioid receptor agonists may alleviate intestinal damage in cardiopulmonary bypass rats by inhibiting the NF‑κB/HIF‑1α pathway Pubmed: 32509012
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY Potential Protective Effect of Dietary Intake of Non-α-Tocopherols on Cellular Aging Markers Mediated by Tumor Necrosis Factor-α in Prediabetes: A Cross … Pubmed: 32509152
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY TNFα Mediates the Interaction of Telomeres and Mitochondria Induced by Hyperglycemia: A Rural Community-Based Cross-Sectional Study Pubmed: 32454945
International Journal of Nanomedicine Effect of Lonicerae japonicae Flos Carbonisata-Derived Carbon Dots on Rat Models of Fever and Hypothermia Induced by Lipopolysaccharide Pubmed: 32606669
Inflammation Tetramethylpyrazine Inhibits Platelet Adhesion and Inflammatory Response in Vascular Endothelial Cells by Inhibiting P38 MAPK and NF-κB Signaling Pathways
Pharma Nutrition Natural sources, dopaminergic and non-dopaminergic agents for therapeutic assessment of Parkinsonism in rat model
Indian Journal of Animal Sciences Peripheral concentrations of metabolic and inflammatory indicators during transition period and their relationship with postpartum clinical endometritis in dairy …
Food & Function Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial …
Possible Role of Statins on the Inflammatory Biomarkers in Patients With Periodontal Disease: A Cross-Sectional Study
Biological Rhythm Research Integrated effects of season and parturition-associated stress on the inflammatory response and metabolic status in Sahiwal (Bos Indicus) cows
Journal of Biochemical and Molecular Toxicology Vitamin D3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti‐inflammatory actions by remodeling cellular …
Biotechnology & Biotechnological Equipment Honokiol inhibits inflammation and endoplasmic reticulum stress in a rat model of pregnancy-induced hypertension
Journal of Functional Foods Polyphenolic extracts from Wushan tea leaves attenuate hepatic injury in CCl4-treated mice
Strawberry (Fragaria x ananassa) leaf extract reduces brain damage in diabetic male rats
The Journal of Nutritional Biochemistry Supplementation of endogenous Ahr ligands reverses insulin resistance and associated inflammation in an insulin-dependent diabetic mouse model
Journal of Diabetes Research Changes and Risk Factors of Skeletal Muscle Mass and Strength in Patients with Type 2 Diabetes over 60 Years Old: A Cross-Sectional Study from China
Applied materials today Tanshinone IIA-loaded aligned microfibers facilitate stem cell recruitment and capillary formation by inducing M2 macrophage polarization
letter in applied nanobioscience Phytochemical and Toxicological Effect of Ethanol Extract of Heliotropium Indicum on Liver of Male Albino Rats
Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort
Phytomedicine Menthacarin attenuates experimental colitis
Impact of Pharmacotherapy to decrease Interleukin-6 in patients with chronic rhinosinusitis without nasal polyp
The Effects of Naringin on Cigarette Smoke-Induced Dynamic Changes in Oxidation/Antioxidant System in Lung of Mice
HMGB1 and inflammatory cytokines in experimental acute lung injury induced in rabbits
Anti-inflammatory effects of functional milk drink enriched with soya bean sprout protein in breastfeeding mothers
中国应用生理学杂志 丹参对非酒精性脂肪肝Th17细胞及相关细胞因子的影响*
EC NEUROLOGY Malted Barley Ameliorated Spinal Cord Injuries of Offspring of Hypercholesterolemic Mother Rats
Toxicol Appl Pharmacol Astragaloside IV protects against retinal iron overload toxicity through iron regulation and the inhibition of MAPKs and NF-¦ÊB activation 33285147
Journal of Burn Care & Research Umbilical cord mesenchymal stem cells (hUCMSCs) for inflammatory regulation after excision and grafting of severe burn wounds in rats 33313794
Evidence-based Complementary and Alternative Medicine Investigation of the Synergistic Effect of Brown Sugar, Longan, Ginger, and Jujube (Brown Sugar Longan Ginger Tea) on Antioxidation and Anti-Inflammation?¡­ 33343673
Nutrients AphaMax?, an Aphanizomenon Flos-Aquae Aqueous Extract, Exerts Intestinal Protective Effects in Experimental Colitis in Rats 33256017
Int J Mol Med Astragaloside IV alleviates silica?induced pulmonary fibrosis via inactivation of the TGF?¦Â1/Smad2/3 signaling pathway 33448318
Biochem Pharmacol Inactivation of Wnt/¦Â-catenin/renin angiotensin axis by tumor necrosis factor-alpha inhibitor, infliximab, ameliorates CKD induced in rats 33482150
Stem Cell Reviews and Reports Prospects on the Potential In Vitro Regenerative Features of Mechanically Treated-Adipose Tissue for Osteoarthritis Care 33469783
Scientific Reports Ultra-purified alginate gel implantation decreases inflammatory cytokine levels, prevents intervertebral disc degeneration, and reduces acute pain after discectomy 33436742
EUROPEAN JOURNAL OF PHARMACOLOGY Gliclazide alters macrophages polarization state in diabetic atherosclerosis in vitro via blocking AGE-RAGE/TLR4-reactive oxygen species-activated NF-k¦Â nexus 33460615
Nature Communications A DNA origami-based aptamer nanoarray for potent and reversible anticoagulation in hemodialysis 33441565
physiological reports Impact of synthetic surfactant CHF5633 with SP©\B and SP©\C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome 33403805
Life Sci Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats 33577848
J Pediatr Urol Protective effects of hydrogen rich saline solution on ventral penile Mathieu type flap with penile tourniquet application in rats 33608226
J Biochem Mol Toxicol Concanavalin A induces apoptosis in a dose©\dependent manner by modulating thiol/disulfide homeostasis in C6 glioblastoma cells 33604990
Int Immunopharmacol Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways 33571746
european journal of clinical nutrition? Effect of Lactobacillus casei on lipid metabolism and intestinal microflora in patients with alcoholic liver injury 33514869
Biomed Pharmacother Qingfei oral liquid inhibited autophagy to alleviate inflammation via mTOR signaling pathway in RSV-infected asthmatic mice 33706133
Int Immunopharmacol Ginkgolide A attenuates sepsis-associated kidney damage via upregulating microRNA-25 with NADPH oxidase 4 as the target 33677255
Drug Des Devel Ther Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPAR¦Ã-Integrin ¦Áv¦Â5 Signaling Pathway 33654384
bmc pediatrics Factors associated with neurodevelopment in preterm infants with systematic inflammation 33685414
INFLAMMATION Acid Sphingomyelinase and Acid ¦Â-Glucosidase 1 Exert Opposite Effects on Interleukin-1¦Â-Induced Interleukin 6 Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes 33665756
TOXICOLOGY IN VITRO Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells 33675893
MOLECULAR BIOLOGY REPORTS The growth-inhibitory effects of pawpaw (Asimina triloba [L.] Dunal) roots, twigs, leaves, and fruit against human gastric (AGS) and cervical (HeLa) cancer cells and 33630206
Sci Rep Association between MIF gene promoter rs755622 and susceptibility to coronary artery disease and inflammatory cytokines in the Chinese Han population 33850223
Am J Transl Res From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis 33841664
Biochem Cell Biol Formononetin protects against concanavalin-A-induced autoimmune hepatitis in mice through its anti-apoptotic and anti-inflammatory properties 33749318
Hum Exp Toxicol Alamandine significantly reduces doxorubicin-induced cardiotoxicity in rats 33882726
NEUROSCIENCE RESEARCH Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats 33785408
BIOMATERIALS Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration 33813259
Biomed Pharmacother Macro- and microtranscriptomic evidence of the monocyte recruitment to regenerating liver after partial hepatectomy in mouse model 33765583
Cell Death & Disease Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization 34006822
Probiotics Antimicrob Proteins Characterization of Iturin V, a Novel Antimicrobial Lipopeptide from a Potential Probiotic Strain Lactobacillus sp. M31 33987819
FASEB Bioadv Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high©\fat diet©\fed hyperglycemic rabbits 33977232
Life Sci Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-¦ÊB p65 mediated modulation of microglia polarization 33965378
Orthop Surg Proline©\Serine¨CThreonine Phosphatase©\Interacting Protein 2 Alleviates Diabetes Mellitus©\Osteoarthritis in Rats through Attenuating Synovial Inflammation and?¡­ 33939302
Biochem Cell Biol CLEC5A knockdown protects against the cardiac dysfunction after Myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation?¡­ 33939927
Biomed Pharmacother Captopril downregulates expression of Bax/cytochrome C/caspase-3 apoptotic pathway, reduces inflammation, and oxidative stress in cisplatin-induced acute?¡­ 33945910
Sci Rep Corrosion Resistance of Graphene oxide/Silver Coatings on Ni¨CTi alloy and Expression of IL-6 and IL-8 in Human O... 32094428
Nephron Dexmedetomidine Exerts Renal Protective Effect by Regulating the PGC-1¦Á/STAT1/IRF-1 Axis 33965939
Drug Design Development and Therapy Effects of Systemic Lidocaine on Postoperative Recovery Quality and Immune Function in Patients Undergoing Laparoscopic Radical Gastrectomy 33976537
Stem Cell Research & Therapy Consecutive daily administration of intratracheal surfactant and human umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced lung?¡­ 33933128
Int J Clin Pract Serum Galectin©\3 Levels in Patients with Psoriasis 34137138
Brain Res Bull Melatonin ameliorates anxiety-like behaviors induced by sleep deprivation in mice: role of oxidative stress, neuroinflammation, autophagy and apoptosis 34144202
Clin Res Hepatol Gastroenterol Cellular Communication Network Factor 1 (CCN1) Knockdown Exerts a Protective Effect for Hepatic Ischemia/Reperfusion Injury by Deactivating the MEK/ERK?¡­ 34144219
IUBMB Life HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1 34117711
Exp Eye Res Ameliorative effects and mechanisms of salvianic acid A on retinal iron overload in vivo and in vitro 34058232
Chem Biol Interact Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy 34051206
Med Sci Monit Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating ¡­ 34059615
Biological Chemistry HDAC8 promotes daunorubicin resistance of human acute myeloid leukemia cells via regulation of IL-6 and IL-8 33938176
Stem Cells International The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin?¡­ 33381190
BioMed Research International Ultrashort Wave Combined with Human Umbilical Cord Mesenchymal Stem Cell (HUC-MSC) Transplantation Inhibits NLRP3 Inflammasome and Improves?¡­ 33376718
Evidence-Based Complementary and Alternative Medicine Zisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling?¡­ 33505502
Oxidative Medicine and Cellular Longevity Yixin-Shu Capsules Ameliorated Ischemia-Induced Heart Failure by Restoring Trx2 and Inhibiting JNK/p38 Activation 33643519
Pharmaceutics PK/PD Modeling of the PDE7 Inhibitor¡ªGRMS-55 in a Mouse Model of Autoimmune Hepatitis. Pharmaceutics 2021, 13, 597 33919375
cells The Effect of the Clenbuterol¡ª¦Â2-Adrenergic Receptor Agonist on the Peripheral Blood Mononuclear Cells Proliferation, Phenotype, Functions, and Reactive Oxygen?¡­ 33920705
Antioxidants Hidrox? Roles in Neuroprotection: Biochemical Links between Traumatic Brain Injury and Alzheimer's Disease 34065584
Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/ROR¦Á/NF-¦ÊB signaling pathways 34162146
Continuous Veno-Venous Hemofiltration (CVVH) Improves Iron Metabolism Disorders in Patients With Sepsis: A Single-Center Prospective Cohort Study
Berberine Attenuates Neonatal Sepsis in Rats By Inhibiting FOXA1 and NF-¦ÊB Signaling Transduction Via The Induction of miR-132-3p
researchsquare Modulation of Oxidative and Nitrosative Stress Attenuates Microvascular Hyperpermeability in Ovine Model of Pseudomonas Aeruginosa Sepsis
Annals of the Romanian Society for Cell Biology Comparative Study on the Pro-Inflammatory Activity of Turmeric (Curcuma longa) and flaxseed (Linumusitatissimum)
Amplified Antitumor Efficacy By A Targeted Drugs Retention and Chemosensitization Strategies-Based ¡°Combo¡± Nanoagent Together With PD-L1 Blockade In?¡­
Saudi Pharmaceutical Journal CoQ10 augments candesartan protective effect against tourniquet-induced hind limb ischemia-reperfusion: involvement of non-classical RAS and ROS?¡­
Veterinary World Comparative evaluation of cytokine and acute-phase protein concentrations in sera of dairy cows with subclinical and clinical ketosis as a different view of the ¡­
Mediators of Inflammation Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of ¦Á1, 3 ¡­
biomolecules Treadmill Running Changes Endothelial Lipase Expression: Insights from Gene and Protein Analysis in Various Striated Muscle Tissues and Serum
Cancer Lett Photodynamic therapy induces human esophageal carcinoma cell pyroptosis by targeting the PKM2/caspase-8/caspase-3/GSDME axis 34256094
J Pharm Pharmacol Alamandine protects against renal ischaemia–reperfusion injury in rats via inhibiting oxidative stress 34244746
J Nanobiotechnology Amplified antitumor efficacy by a targeted drug retention and chemosensitization strategy-based “combo” nanoagent together with PD-L1 blockade in … 34225744
PPAR Research Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment … 34306045
Naunyn Schmiedebergs Arch Pharmacol Amelioration of autoimmunity and inflammation by zinc oxide nanoparticles in experimental rheumatoid arthritis 34236500
Front Pharmacol In Silico and In Vivo Studies on the Mechanisms of Chinese Medicine Formula (Gegen Qinlian Decoction) in the Treatment of Ulcerative Colitis 34177580
J Cell Mol Med Puerarin attenuates intracerebral hemorrhage‐induced early brain injury possibly by PI3K/Akt signal activation‐mediated suppression of NF‐κB pathway 34180121
PLoS One Could serum zonulin be an intestinal permeability marker in diabetes kidney disease? 34170951
Intensive Care Medicine Experimental Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … 34169407
Aging Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular … 34315133
Peptides Alamandine, a derivative of angiotensin-(1-7), alleviates sepsis-associated renal inflammation and apoptosis by inhibiting the PI3K/Ak and MAPK pathways 34400214
Lab Med Interleukin-6 and Serum/Fecal Calprotectin as Useful Specific Markers for Monitoring Rheumatic Diseases: A Pilot Study 34405886
Sci Rep Talaromyces marneffei and nontuberculous mycobacteria co-infection in HIV-negative patients 34376749
Am J Transl Res Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma 34377237
Transl Vis Sci Technol Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes 34357381
J Burn Care Res Efficacy of Acupuncture on Pain Mechanisms, Inflammatory Responses, and Wound Healing in the Acute Phase of Major Burns: An Experimental Study on Rats 34309681
Inflammation Berberine Attenuates Neonatal Sepsis in Mice By Inhibiting FOXA1 and NF-κB Signal Transduction Via the Induction of MiR-132-3p 34523052
Mol Med Rep Emodin inhibits the progression of acute pancreatitis via regulation of lncRNA TUG1 and exosomal lncRNA TUG1 34498715
Int Immunopharmacol Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway 34464887
J Nanobiotechnology The neuroprotective effect of pretreatment with carbon dots from Crinis Carbonisatus (carbonized human hair) against cerebral ischemia reperfusion injury 34454522
JOURNAL OF PHARMACY AND PHARMACOLOGY Potential therapeutic efficacy of pachymic acid in chronic kidney disease induced in rats: role of Wnt/β-catenin/renin–angiotensin axis 34549301
BIOMEDICINE & PHARMACOTHERAPY Ginkgo biloba extract (EGb 761) mitigates methotrexate-induced testicular insult in rats: Targeting oxidative stress, energy deficit and spermatogenesis 34560547
JOURNAL OF ETHNOPHARMACOLOGY Ethanolic extract of Pyrus pashia buch ham ex. D. Don (kainth): A bioaccessible source of polyphenols with anti-inflammatory activity in vitro and in vivo 34517063
Neurosci Lett Flavin-containing monooxygenase 1 deficiency promotes neuroinflammation in dopaminergic neurons in mice 34500002
Eur J Pharmacol Hydralazine attenuates renal inflammation in diabetic rats with ischemia/reperfusion acute kidney injury 34478692
Int Immunopharmacol Diacerein ameliorates testosterone-induced benign prostatic hyperplasia in rats: Effect on oxidative stress, inflammation and apoptosis 34450401
Biomed Pharmacother Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation in rats 34426252
Life Sci Ingestion of mannose ameliorates thioacetamide-induced intrahepatic oxidative stress, inflammation and fibrosis in rats 34637794
The Journal of Clinical Endocrinology & Metabolism High Hemoglobin glycation index is associated with telomere attrition independent of HbA1c, mediating by TNFα 34562085
J Thromb Haemost Transfusion of fresh washed platelets does not prevent experimental polymicrobial‐induced septic shock in mice 34752015
J Cell Mol Med Stress‐induced phosphoprotein 1 restrains spinal cord ischaemia‐reperfusion injury by modulating NF‐κB signalling 34734476
Transl Psychiatry Associations between expression of indoleamine 2, 3-dioxygenase enzyme and inflammatory cytokines in patients with first-episode drug-naive … 34802039
Biofactors Vitamin D3 enhances the effects of omega‐3 oils against metabolic dysfunction‐associated fatty liver disease in rat 34767670
J Ethnopharmacol Bai-Hu-Tang regulates endothelin-1 and its signalling pathway in vascular endothelial cells 34752899
J Ethnopharmacol Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and … 34699947
Mol Immunol MiR-142-5p directly targets cyclin-dependent kinase 5-mediated upregulation of the inflammatory process in acquired middle ear cholesteatoma 34875451
Neurosci Let Fingolimod protects against cerebral ischemia reperfusion injury in rats by reducing inflammatory cytokines and inhibiting the activation of p38 MAPK and NF-κB … 34942319
Brain Sci Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial … 34942919
Environmental Research In-vitro oxidative potential and inflammatory response of ambient PM2. 5 in a rural region of Northwest China: Association with chemical compositions and … 34863982
Alzheimers Res Ther Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and … 34844651
World J Gastroenterol Calycosin attenuates severe acute pancreatitis-associated acute lung injury by curtailing high mobility group box 1-induced inflammation 34908806
Experimental and Therapeutic Medicine Autonomic regulation of imbalance‑induced myocardial fibrosis and its mechanism in rats with cirrhosis 34373726
Journal of Food and Nutrition Research Effects of a Fermented Grape Combined with Specified Fruits and Vegetables or Their Extracts on Anti-aging and Anti-inflammatory Status: A Randomized … 33755227
Journal of Immunology Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats 34568500
Biomedicines Sphingosine 1-Phosphate (S1P) in the Peritoneal Fluid Skews M2 Macrophage and Contributes to the Development of Endometriosis 34829748
Pharmaceutics Nitric-Oxide-Releasing Dexamethasone Derivative NCX-1005 Improves Lung Function and Attenuates Inflammation in Experimental Lavage-Induced ARDS 34959373
IUBMB Life Endogenous dipeptide‐carnosine supplementation ameliorates hypobaric hypoxia‐induced skeletal muscle loss via attenuating endoplasmic reticulum stress … 34455667
Respir Res Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice 34789242
Neuropsychiatric Disease and Treatment The Association Between Hypoxia Improvement and Electroconvulsive Therapy for Major Depressive Disorder 34588778
Oxidative Medicine and Cellular Longevity Roles of Suaeda vermiculata Aqueous-Ethanolic Extract, Its Subsequent Fractions, and the Isolated Compounds in Hepatoprotection against Paracetamol … 34567411
Carbohydrate Polymers The anti-inflammatory activity of specific-sized hyaluronic acid oligosaccharides 34823813
Antioxidants Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer's Disease 34829535
Biomedicines Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes 34829910
Mol Med Rep Long non-coding RNA NEAT1 participates in ventilator-induced lung injury by regulating miR-20b expression Pubmed:34981816
Int J Nanomedicine Protective Effects of Carbon Dots Derived from Armeniacae Semen Amarum Carbonisata Against Acute Lung Injury Induced by Lipopolysaccharides in Rats Pubmed:35023915
Poult Sci Effects of different selenium sources on duodenum and jejunum tight junction network and growth performance of broilers in a model of fluorine-induced … Pubmed:35066382
Poult Sci Salmonella phage CKT1 significantly relieves the body weight loss of chicks by normalizing the abnormal intestinal microbiome caused by hypervirulent … Pubmed:35063807
Bioengineered Inflammation promotes erythropoietin induced vascular calcification by activating p38 pathway Pubmed:35168476
J Biochem Mol Toxicol Silencing of IGF2BP1 restrains ox‐LDL‐induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages Pubmed:35179253
Cell Death Discov Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury Pubmed:35110526
J Dairy Sci Intake of Bifidobacterium lactis Probio-M8 fermented milk protects against alcoholic liver disease Pubmed:35086715
Exp Biol Med (Maywood) Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat Pubmed:35068213
Peptides Osteocrin alleviates cardiac hypertrophy via attenuating oxidative stress Pubmed:35218795
Int Immunopharmacol LncRNA KCNQ1OT1 attenuates myocardial injury induced by hip fracture via regulating of miR-224-3p/GATA4 axis Pubmed:35217336
PLoS One Investigation of the active ingredients and pharmacological mechanisms of Porana sinensis Hemsl. Against rheumatoid arthritis using network pharmacology … Pubmed:35235611
Eur Rev Med Pharmacol Sci Evaluation of hepatoprotective effect of Nebivolol and sodium copper Chlorophyllin on CCL4-induced hepatotoxicity in mice Pubmed:35302221
Molecular Biotechnology MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages Pubmed:35435591
Clinical Oral Investigations Evaluation of salivary and serum methylated arginine metabolites and nitric oxide synthase in advanced periodontitis patients Pubmed:35426000
Theranostics Combating multidrug resistance and metastasis of breast cancer by endoplasmic reticulum stress and cell-nucleus penetration enhanced … Pubmed:35401832
Biomed Pharmacother Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats Pubmed:35430394
Antioxidants (Basel) Effect of Alpha-Lipoic Acid on Rat Ventricles and Atria under LPS-Induced Oxidative Stress Pubmed:35453419
Drug Des Devel Ther Lung-Protective Effects of Lidocaine Infusion on Patients with Intermediate/High Risk of Postoperative Pulmonary Complications: A Double-Blind Randomized … Pubmed:35422611
PLoS One Effects of maternal ritodrine hydrochloride administration on the heart rate of preterm fetal sheep with intraamniotic inflammation Pubmed:35358222
Journal of Nanobiotechnology Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM Pubmed:35351131
Clin Oral Investig Influence of periodontal inflammation on tryptophan-kynurenine metabolism: a cross-sectional study Pubmed:35588020
Molecules 5, 2′-Dibromo-2, 4′, 5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 Protein Pubmed:35566232
Evid Based Complement Alternat Med Loureirin B Alleviates Myocardial Ischemia/Reperfusion Injury via Inhibiting PAI-1/TGF-β1/Smad Signaling Pathway Pubmed:35535157
Life Sci Infliximab and/or MESNA alleviate doxorubicin-induced Alzheimer's disease-like pathology in rats: A new insight into TNF-α/Wnt/β-catenin signaling pathway Pubmed:35523286
Eur J Pharmacol Potential cardioprotective effect of octreotide via NOXs mitigation, mitochondrial biogenesis and MAPK/Erk1/2/STAT3/NF-kβ pathway attenuation in isoproterenol … Pubmed:35500641
J Clin Med Endometrial Dysbiosis Is Related to Inflammatory Factors in Women with Repeated Implantation Failure: A Pilot Study Pubmed:35566605
American Journal of Translational Research Curcumin treats endometriosis in mice by the HIF signaling pathway Pubmed:35559378
Mol Immunol Oridonin alleviates kanamycin-related hearing loss by inhibiting NLRP3/caspase-1/gasdermin D-induced inflammasome activation and hair cell pyroptosis Pubmed:35749835
J Biomed Mater Res B Appl Biomater Hybrid system with stable structure of hard/soft tissue substitutes induces re‐osseointegration in a rat model of biofilm‐mediated peri‐implantitis Pubmed:35620882
J Inflamm Res The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca2+/CaMKII/CREB Pathway in Rats Pubmed:35645576
Int J Mol Sci Antiosteoporotic Nanohydroxyapatite Zoledronate Scaffold Seeded with Bone Marrow Mesenchymal Stromal Cells for Bone Regeneration: A 3D In Vitro Model Pubmed:35682677
Journal of Biomaterials Applications Photobiomodulation associated with lipid nanoparticles and hyaluronic acid accelerate the healing of excisional wounds Pubmed:35705485
Evidence-Based Complementary and Alternative Medicine Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction Pubmed:35722150
Asian Journal of Surgery Lipid emulsions prevent postoperative abdominal adhesions Pubmed:35688763
Evaluation of Tubular Dysfunction Using Urine Biomarkers in Children with COVID-19 Pubmed:35110086
Experimental and Therapeutic Medicine Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosis Pubmed:35126715
Neuromodulation: Technology at the Neural Interface Transcutaneous Electrical Acustimulation Improved the Quality of Life in Patients With Diarrhea-Irritable Bowel Syndrome Pubmed:35088760
Antioxidants Blue Light Alters the Composition of the Jejunal Microbiota and Promotes the Development of the Small Intestine by Reducing Oxidative Stress Pubmed:35204158
Antioxidants Bio-Evaluation of the Wound Healing Activity of Artemisia judaica L. as Part of the Plant's Use in Traditional Medicine; Phytochemical, Antioxidant, Anti-Inflammatory … Pubmed:35204215
Veterinary World Pro-inflammatory cytokine release from chicken peripheral blood mononuclear cells stimulated with lipopolysaccharide Pubmed:35698506
Medicina Plasma Concentrations of Cytokines in Patients with Combined Hyperlipidemia and Atherosclerotic Plaque before Treatment Initiation—A Pilot Study Pubmed:35630041
Pharmaceuticals Discovery of Nitro-azolo[1,5-a]pyrimidines with Anti-Inflammatory and Protective Activity against LPS-Induced Acute Lung Injury Pubmed:35631365
International Journal of Molecular Sciences Regulation of Neuroinflammatory Signaling by PPARγ Agonist in Mouse Model of Diabetes Pubmed:35628311
Biomedicine & Pharmacotherapy Bicyclol ameliorates advanced liver diseases in murine models via inhibiting the IL-6/STAT3 signaling pathway Pubmed:35658240
Journal of Integrative Medicine Salvadora persica extract attenuates cyclophosphamide-induced hepatorenal damage by modulating oxidative stress, inflammation and apoptosis in rats Pubmed:35643766
Journal of Pharmaceutical Research International Effectiveness of Turmeric and Extra Virgin Olive Oil in the Management of IL 6 and IL 10 in Healthy Mice
researchsquare Dexmedetomidine Attenuates Hyperalgesia Induced By Brachial Plexus Root Avulsion By Restoring The GLT-1 Function Via PKA Signaling
ResearchSquare LncRNA KCNQ10T1 shuttled by bone marrow mesenchymal stem cells-derived exosome inhibits sepsis via regulation of miR-154-3p/RNF19A axis
Biointerface Research in Applied Chemistry Promising Therapeutic Efficacy of Trigonella-foenum graecum and Bone Marrow-Derived Mesenchymal Stem Cells on Skeletal Muscle Atrophy in Experimental …
Protective effects of carbon dots derived from Rhei radix et rhizoma carbonisata on DSS (dextran sulfate sodium)-induced ulcerative colitis
Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS
Evaluation of the Effects of Empagliflozin on Acute Lung Injury in Rat Intestinal Ischemia-Reperfusion Model
Journal of Traditional Chinese Medical Sciences Qinzhi Zhudan formula improves memory and alleviates neuroinflammation in vascular dementia rats partly by inhibiting the TNFR1-mediated TNF pathway
Intensive Care Research Evaluating the Roles of sCD14 and sCD14-ST in Diagnosing COPD and Predicting an Acute Exacerbation of COPD
Comparative Clinical Pathology Mechanisms underlying the hepatoprotective effect of silymarin on fluoxetine-induced liver injury in rats: the implication of peroxisome proliferator–activated receptor …
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