Recombinant Glial Fibrillary Acidic Protein (GFAP)

Intermediate Filament Protein

  • Product No.RPA068Hu05
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationCytoplasm
  • Predicted Molecular Mass26.6kDa
  • Accurate Molecular Mass27kDa(Analysis of differences refer to the manual)
  • Residues & TagsMet1~Arg201 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point8.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 143  US$ 358  US$ 716  US$ 2148  US$ 5370 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Journal of Occupational Health Effects of Exposure to 1-Bromopropane on Astrocytes and Oligodendrocytes in Rat Brain Pubmed: 23183024
Morfovirtual 2014 EFECTO PROTECTOR DEL TRATAMIENTO CON NEUROEPO SOBRE LA GLIA DE LA CORTEZA CEREBRAL EN RATONES TRANSGéNICOS CON LA ENFERMEDAD DE ALZHEIMER. Sld:Source
Annals of Anatomy Effect of memantine, a NMDA receptor blocker, on ethambutol-induced retinal injury PubMed: 26704355
Mediators of Inflammation IL-4 Inhibits IL-1β-Induced Depressive-Like Behavior and Central Neurotransmitter Alterations PubMed: 26417153
Neurochem Res Protective Effect of Oral Hesperetin Against Unilateral Striatal 6-Hydroxydopamine Damage in the Rat PubMed: 26700436
Cell Mol Neurobiol Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson’s Disease PubMed: 26119304
Sleep and Biological Rhythms Relationship of orexin (hypocretin) system and astrocyte activation in Parkinson&#039;s disease with hypersomnolence Doi: 10.1111
Cellular and Molecular Neurobiology Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson’s Disease Pubmed:26119304
Ann Anat Effect of memantine: A NMDA receptor blocker, on ethambutol-induced retinal injury Pubmed:26704355
United States Patent Application ESTROGENIC COMPONENTS FOR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS y2016:0101116.html
Clinical Research Human plasma glial fibrillary acidic protein and heat shock protein 27 concentrations in acute moderate-intensity aerobic exercise with different duration a825e1e27b0221df9a627769c0f614432e92.pdf
Medical Journal of Indonesia Comparison of GFAP and HSP27 concentrations in acute moderate-intensity aerobic exercise of different duration 2031884
Peptides. Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms. pubmed:27777064
european journal of pharmacology Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms. pubmed:27915041
european journal of pharmacology Troxerutin exerts neuroprotection in 6-hydroxydopamine lesion rat model of Parkinson's disease: Possible involvement of PI3K/ERβ signaling. pubmed:28284752
biomedicine & pharmacotherapy Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. pubmed:28199883
J Endocrinol.  Estrogen receptors and estetrol-dependent neuroprotective actions: a pilot study. pubmed:27799463
IOS Press Content Library An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's … articles:journal-of-alzheimers-disease
Tierärztliche Hochschule Hannover Evaluierung von Biomarkern im Liquor cerebrospinalis bei paraplegischen Hunden mit Rückenmarksverletzung :
Nigerian Journal of Clinical Practice Utilization of Glial Fibrillary Acidic Protein and Galectin-3 in the Diagnosis of Cerebral Infarction Patients with Normal Cranial Tomography pubmed:28406123
Cytokine Soy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects pubmed:29102164
Biomedicine & pharmacotherapy Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms pubmed:28061403
Experimental gerontology The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling. pubmed:29107062
Pesticide Biochemistry and Physiology Acrolein-mediated neurotoxicity in growing Wistar male rats Pubmed:30033014
Journal of Perinatal Medicine Mechanisms of death in structurally normal stillbirths Pubmed: 30231013
Metabolic Brain Disease Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms Pubmed: 30456649
Metabolic Brain Disease Trigonelline protects hippocampus against intracerebral Aβ (1–40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms Pubmed: 30421246
博士论文 INSTITUTO DE CIENCIAS BÁSICAS Y PRECLÍNICAS “VICTORIA DE GIRÓN” DEPARTAMENTO DE HISTOLOGÍA
Medicina The Administration of the New Pyrimidine Derivative—4-{2-[2-(3, 4-Dimethoxyphenyl)-Vinyl]-6-Ethyl-4-Oxo-5-Phenyl-4H-Pyrimidine-1-Il} Benzsulfamide Restores the …
Open Access Macedonian Journal of Medical Sciences Inhibition of Receptor for Advanced Glycation End Products as New Promising Strategy Treatment in Diabetic Retinopathy Pubmed: 32165929
NEUROPSYCHOBIOLOGY Diosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms Pubmed: 32526752
JAMA Surgery Intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment Pubmed: 28593326
Acta Histochemica Quercetin mitigates monosodium glutamate-induced excitotoxicity of the spinal cord motoneurons in aged rats via p38 MAPK inhibition Pubmed: 32622428
stanbul Med J The Predictive Role of Neurobiochemical Markers in Multiple Sclerosis.
Basic and Clinical Neuroscience Paeonol Protects Against Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease 33995926
pharmacology online PHARMACOLOGICAL SCREENING OF A POTENTIALLY EFFECTIVE COMPOUND FOR THE TREATMENT OF CHRONIC TRAUMATIC ENCEPHALOPATHY?¡­
Neuropeptides The bee venom active compound melittin protects against bicuculline-induced seizures and hippocampal astrocyte activation in rats 34808488
Neural Plast P2Y2 Receptor Mediated Neuronal Regeneration and Angiogenesis to Affect Functional Recovery in Rats with Spinal Cord Injury Pubmed:35154311
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA068Hu05 Recombinant Glial Fibrillary Acidic Protein (GFAP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA068Hu02 Recombinant Glial Fibrillary Acidic Protein (GFAP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA068Hu04 Recombinant Glial Fibrillary Acidic Protein (GFAP) Positive Control; Immunogen; SDS-PAGE; WB.
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LAA068Hu81 FITC-Linked Polyclonal Antibody to Glial Fibrillary Acidic Protein (GFAP) WB; IHC; ICC; IF.
MAA068Hu22 Monoclonal Antibody to Glial Fibrillary Acidic Protein (GFAP) WB; IHC; ICC; IP.
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