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Cofilin 1 (CFL1)

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CFL; p18; N-Cofilin; 18 kDa phosphoprotein; Cofilin 1, Non Muscle

Cofilin 1 (CFL1)
CCC B559
HGNC 1874
MGI 101757
PubMed 8800436
RGD 69285
UniProt P23528
Wiki Cofilin_1

Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. CFL1 is a part of the ADF/cofilin family.Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.One group reports that reelin signaling leads to serine3-phosphorylation of cofilin-1, and this interaction may play a role in the reelin-related regulation of neuronal migration.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB559Hu01 Recombinant Cofilin 1 (CFL1) Positive Control; Immunogen; SDS-PAGE; WB.
APB559Hu01 Active Cofilin 1 (CFL1) Cell culture; Activity Assays.
Antibodies PAB559Hu01 Polyclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
MAB559Hu22 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC/IF
MAB559Hu21 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
MAB559Hu23 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
MAB559Hu24 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
MAB559Hu25 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
MAB559Hu27 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
Assay Kits SEB559Hu ELISA Kit for Cofilin 1 (CFL1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB559Hu CLIA Kit for Cofilin 1 (CFL1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB559Mu01 Recombinant Cofilin 1 (CFL1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB559Mu02 Recombinant Cofilin 1 (CFL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB559Mu01 Polyclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
PAB559Mu02 Polyclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
Assay Kits SEB559Mu ELISA Kit for Cofilin 1 (CFL1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB559Mu CLIA Kit for Cofilin 1 (CFL1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB559Ra01 Recombinant Cofilin 1 (CFL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB559Ra01 Polyclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
MAB559Ra21 Monoclonal Antibody to Cofilin 1 (CFL1) WB; IHC; ICC; IP.
Assay Kits SEB559Ra ELISA Kit for Cofilin 1 (CFL1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB559Ra CLIA Kit for Cofilin 1 (CFL1) Chemiluminescent immunoassay for Antigen Detection.
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  7. , Submitted (MAR-2005) to UniProtKB
  8. , Submitted (DEC-2008) to UniProtKB
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