Fibroblast Growth Factor 7 (FGF7)

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KGF; HBGF7; Keratinocyte Growth Factor; Heparin-binding growth factor 7

Fibroblast Growth Factor 7 (FGF7)

Keratinocyte growth factor is a protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.

Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA636Hu01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
APA636Hu01 Active Fibroblast Growth Factor 7 (FGF7) Cell culture; Activity Assays.
Antibodies PAA636Hu01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
MAA636Hu22 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
Assay Kits SEA636Hu ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA636Mu01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
RPA636Mu02 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA636Mu01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
PAA636Mu02 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
Assay Kits SEA636Mu ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA636Ra01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA636Ra01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
MAA636Ra21 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
Assay Kits CEA636Ra ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA636Po01 Recombinant Fibroblast Growth Factor 7 (FGF7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA636Po01 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
MAA636Po21 Monoclonal Antibody to Fibroblast Growth Factor 7 (FGF7) WB; IHC; ICC; IP.
Assay Kits SEA636Po ELISA Kit for Fibroblast Growth Factor 7 (FGF7) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth."Science 245:752-755(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity."Ann. N. Y. Acad. Sci. 638:62-77(1991) [PubMed] [Europe PMC] [Abstract]
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  8. "The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair."Oncogene 24:5269-5277(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family."J. Biol. Chem. 281:15694-15700(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Fibroblast growth factor signalling: from development to cancer."Nat. Rev. Cancer 10:116-129(2010) [PubMed] [Europe PMC] [Abstract]