Editing Cluster Of Differentiation 200(CD200)

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Summary	<p>CD200 protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. The MRC OX-2 antigens purified from thymocytes and brain are glycoproteins of a molecular mass of 47,000 and 41,000 daltons containing 33% and 24% carbohydrate, respectively.</p><p>Protein and cDNA sequencing showed that these antigens contain 248 amino acids, of which 202 are likely to be outside the cell, with a single transmembrane sequence and 19 residues on the cytoplasmic side. The extracellular part contains 2 domains with sequence similarities to immunoglobulin domains, establishing MRC OX-2 as a member of the immunoglobulin superfamily.</p>
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