Recombinant Corticotropin Releasing Factor (CRF)

CRH; Corticotropin Releasing Hormone; Corticoliberin

  • Product No.RPA835Mu02
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass44.8kDa
  • Accurate Molecular Mass46kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg28~Arg160 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point7.3
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 152  US$ 380  US$ 760  US$ 2280  US$ 5700 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Toxicology Letters Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic–pituitary–adrenal axis in adult male rats Pubmed:24440345
Bipolar?Disord. Immune dysfunction in bipolar disorder and suicide risk: is there an association between peripheral corticotropin‐releasing hormone and interleukin‐1β? Pubmed:24862833
Peptides Differential stress response in rats subjected to chronic mild stress is accompanied by changes in CRH-family gene expression at the pituitary level Pubmed:25236411
Ann Dermatol Acute Stress-Induced Changes in Follicular Dermal Papilla Cells and Mobilization of Mast Cells:Implications for Hair Growth. pubmed:27746640
Neuroscience Heat stress-induced neuroinflammation and aberration in monoamine levels in hypothalamus are associated with temperature dysregulation pubmed:28663093
Biomed Research International Colonic Transit Time and Gut Peptides in Adult Patients with Slow and Normal Colonic Transit Constipation pubmed:29082242
Biochemical Pharmacology Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats Pubmed:30028991
Frontiers in Pharmacology Vaccinium bracteatum Leaf Extract Reverses Chronic Restraint Stress-Induced Depression-Like Behavior in Mice: Regulation of Hypothalamic-Pituitary … Pubmed:30038568
Toxicology Letters Perfluorooctane sulfonate (PFOS) can alter the hypothalamic-pituitary-adrenal (HPA) axis activity by modifying CRF1 and glucocorticoid receptors Pubmed:29807116
Neuropsychiatric disease and treatment The depressive-like behaviors of chronic unpredictable mild stress-treated mice, ameliorated by Tibetan medicine Zuotai: involvement in the hypothalamic … Pubmed:29379286
BMC Veterinary Research Hypothalamus-pituitary-adrenal axis involves in anti-viral ability through regulation of immune response in piglets infected by highly pathogenic porcine … Pubmed:29540178
Bioscience Research Bioscience Research
FASEB Journal Contribution of DNA methylation in chronic stress–induced cardiac remodeling and arrhythmias in mice Pubmed: 31431066
Aging Cell Altered glucocorticoid metabolism represents a feature of macroph‐aging Pubmed: 32463582
Endocr J Impairment of CRH in the intestinal mucosal epithelial barrier of pregnant Bama miniature pig induced by restraint stress 33408312
CRYOBIOLOGY O-GlcNAc/Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress 33651993
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPA835Mu01 Recombinant Corticotropin Releasing Factor (CRF) Positive Control; Immunogen; SDS-PAGE; WB.
RPA835Mu02 Recombinant Corticotropin Releasing Factor (CRF) Positive Control; Immunogen; SDS-PAGE; WB.
CPA835Mu21 OVA Conjugated Corticotropin Releasing Factor (CRF) Immunogen; SDS-PAGE; WB.
CPA835Mu22 OVA Conjugated Corticotropin Releasing Factor (CRF) Immunogen; SDS-PAGE; WB.
CPA835Mu33 KLH Conjugated Corticotropin Releasing Factor (CRF) Immunogen; SDS-PAGE; WB.
PAA835Mu09 Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC; IP.
PAA835Mu01 Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC; IP.
PAA835Mu02 Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC; IP.
PAA835Mu07 Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC; IP.
PAA835Mu08 Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC; IP.
LAA835Mu81 FITC-Linked Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC; IF.
LAA835Mu71 Biotin-Linked Polyclonal Antibody to Corticotropin Releasing Factor (CRF) WB; IHC; ICC.
MEA835Mu Mini Samples ELISA Kit for Corticotropin Releasing Factor (CRF) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA835Mu ELISA Kit for Corticotropin Releasing Factor (CRF) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA835Mu Multiplex Assay Kit for Corticotropin Releasing Factor (CRF) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA835Mu11 ELISA Kit DIY Materials for Corticotropin Releasing Factor (CRF) Main materials for "Do It (ELISA Kit) Yourself".