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  • KO-Validated
Polyclonal Antibody to Kelch Like ECH Associated Protein 1 (KEAP1)

INrf2; KLHL19; Cytosolic inhibitor of Nrf2; Kelch-like protein 19

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against KEAP1. It has been selected for its ability to recognize KEAP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Environmental Toxicology and Pharmacology Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study pubmed:28192751
Journal of Infection and Chemotherapy Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity Pubmed:29753615
Immunopharmacology and immunotoxicology Protective effect of sesamin in lipopolysaccharide-induced mouse model of acute kidney injury via attenuation of oxidative stress, inflammation, and apoptosis Pubmed: 30488751
International Immunopharmacology S-allyl cysteine protects against lipopolysaccharide-induced acute kidney injury in the C57BL/6 mouse strain: Involvement of oxidative stress and inflammation Pubmed: 30665040
Respiratory physiology & neurobiology Targeting oxidative stress, proinflammatory cytokines, apoptosis and toll like receptor 4 by empagliflozin to ameliorate bleomycin-induced lung fibrosis Pubmed: 31600583
Vet Sci Protective and Therapeutic Effects of Orlistat on Metabolic Syndrome and Oxidative Stress in High-Fat Diet-Induced Metabolic Dysfunction-Associated Fatty Liver … 34822647
Antioxidants (Basel) Hepatoprotective Effect of Bee Bread in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Rats: Impact on Oxidative Stress and Inflammation 34943134
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPL648Hu01 Recombinant Kelch Like ECH Associated Protein 1 (KEAP1) Positive Control; Immunogen; SDS-PAGE; WB.
PAL648Hu01 Polyclonal Antibody to Kelch Like ECH Associated Protein 1 (KEAP1) WB; IHC; ICC/IF
MAL648Hu21 Monoclonal Antibody to Kelch Like ECH Associated Protein 1 (KEAP1) WB; IHC; ICC; IP.
SEL648Hu ELISA Kit for Kelch Like ECH Associated Protein 1 (KEAP1) Enzyme-linked immunosorbent assay for Antigen Detection.
LML648Hu Multiplex Assay Kit for Kelch Like ECH Associated Protein 1 (KEAP1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.