Polyclonal Antibody to Sirtuin 1 (SIRT1)
SIR2L1; Silent Mating Type Information Regulation 2 Homolog 1; NAD-Dependent Deacetylase Sirtuin-1; SIR2-like protein 1; SirtT1 75 kDa fragment
- Product No.PAE912Ra01
- Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- SourcePolyclonal antibody preparation
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- Immunogen RPE912Ra01-Recombinant Sirtuin 1 (SIRT1)
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- Organism Species MoreHomo sapiens (Human), Mus musculus (Mouse)
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
- DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
For more details, please contact local distributors! US$ 266
For more details, please contact local distributors! US$ 380
For more details, please contact local distributors! US$ 950
For more details, please contact local distributors! US$ 3800
For more details, please contact local distributors!
The antibody is a rabbit polyclonal antibody raised against SIRT1. It has been selected for its ability to recognize SIRT1 in immunohistochemical staining and western blotting.
Western blotting: 0.5-2µg/mL;
Optimal working dilutions must be determined by end user.
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
- Antibody Labeling Customized Service
- Protein A/G Purification Column
- Staining Solution for Cells and Tissue
- Positive Control for Antibody
- Tissue/Sections Customized Service
- Phosphorylated Antibody Customized Service
- Western Blot (WB) Experiment Service
- Immunohistochemistry (IHC) Experiment Service
- Immunocytochemistry (ICC) Experiment Service
- Flow Cytometry (FCM) Experiment Service
- Immunoprecipitation (IP) Experiment Service
- Immunofluorescence (IF) Experiment Service
- DAB Chromogen Kit
- SABC Kit
- Long-arm Biotin Labeling Kit
- Real Time PCR Experimental Service
|PLoS One.||SIRT1 Gene Polymorphisms Affect the Protein Expression in Cardiovascular Diseases Plos: Source|
|PLOS ONE||A Novel Role for SIRT-1 in L-Arginine Protection against STZ Induced Myocardial Fibrosis in Rats Pubmed:25501750|
|Journal of Alzheimer's Disease||Serum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment Pubmed:25589731|
|Respirology||Increases in peripheral SIRT1: A new biological characteristic of asthma PubMed: 26040995|
|PLOS ONE||A Remarkable Age-Related Increase in SIRT1 Protein Expression against Oxidative Stress in Elderly: PubMed: 25785999|
|Endocrine||Changes of serum Mir-217 and the correlation with the severity in type 2 diabetes patients with different stages of diabetic kidney disease. pubmed:27522360|
|Naunyn Schmiedebergs Arch Pharmacol||The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury pubmed:28361247|
|International journal of cardiology||A sirtuin 1/MMP2 prognostic index for myocardial infarction in patients with advanced coronary artery disease pubmed:28043667|
|International Journal of Cardiology||Serum concentrations and gene expression of sirtuin 1 in healthy and slightly overweight subjects after caloric restriction or resveratrol supplementation: A randomized trial pubmed:28029409|
|Hepatology International||Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population pubmed:29189974|
|Toxicology and Applied Pharmacology||Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454|
|Chemico-biological Interactions||Magnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction pubmed:28919305|
|Nutrients||Gene Expression of Sirtuin-1 and Endogenous Secretory Receptor for Advanced Glycation End Products in Healthy and Slightly Overweight Subjects after … Pubmed:30037068|
|Experimental Gerontology||Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia Pubmed:30071285|
|Kidney and Blood Pressure Research||The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy Pubmed: 30504713|
|Journal of International Medical Research||Serum and follicular fluid levels of sirtuin 1, sirtuin 6, and resveratrol in women undergoing fertilization: an observational, clinical study Pubmed: 30556451|
|BioMed Research International||Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic …|
|学位论文||Influência do tratamento da doença periodontal na sirtuína 1 e na lectina ligadora de manose em indivíduos com doença arterial coronária|
|Journal of Physics D: Applied Physics||Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility|
|Journal of Geriatric Oncology||Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors Pubmed: 30952517|
|Biomed Research International||Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of … Pubmed: 30956976|
|Journal of Diabetes and its Complications||Vasohibin-1 in T2DM with different UACR|
|Clinical Interventions in Aging||The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis Pubmed: 32214805|
|Compr Psychiatry||Crocin alleviates schizophrenia-like symptoms in rats by upregulating silent information regulator-1 and brain derived neurotrophic factor Pubmed: 33045669|
|Сибирский федеральный университет||Влияние гречневой крупы на сиртуиновую активность у подопытных животных в эксперименте|
|Journal of Cereal Science||Dietary buckwheat enhances sirtuin1 without calorie restriction|
|Catalog No.||Related products for research use of Rattus norvegicus (Rat) Organism species||Applications (RESEARCH USE ONLY!)|
|RPE912Ra01||Recombinant Sirtuin 1 (SIRT1)||Positive Control; Immunogen; SDS-PAGE; WB.|
|RPE912Ra02||Recombinant Sirtuin 1 (SIRT1)||Positive Control; Immunogen; SDS-PAGE; WB.|
|PAE912Ra01||Polyclonal Antibody to Sirtuin 1 (SIRT1)||WB; IHC; ICC; IP.|
|MAE912Ra21||Monoclonal Antibody to Sirtuin 1 (SIRT1)||WB; IHC; ICC; IP.|
|SEE912Ra||ELISA Kit for Sirtuin 1 (SIRT1)||Enzyme-linked immunosorbent assay for Antigen Detection.|
|SCE912Ra||CLIA Kit for Sirtuin 1 (SIRT1)||Chemiluminescent immunoassay for Antigen Detection.|