Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a)
HIF1-A; MOP1; PASD8; Basic Helix-Loop-Helix Transcription Factor; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78
- Product No.PAA798Ra01
- Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- SourcePolyclonal antibody preparation
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- Immunogen RPA798Ra01-Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a)
- Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
- Organism Species MoreHomo sapiens (Human), Mus musculus (Mouse)
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
- DownloadInstruction Manual
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For negotiated price and more details, please contact local distributors! US$ 239 FREE TRIAL
For negotiated price and more details, please contact local distributors! US$ 342 FREE TRIAL
For negotiated price and more details, please contact local distributors! US$ 1368 FREE TRIAL
For negotiated price and more details, please contact local distributors! US$ 102600 FREE TRIAL
For negotiated price and more details, please contact local distributors!
The antibody is a rabbit polyclonal antibody raised against HIF1a. It has been selected for its ability to recognize HIF1a in immunohistochemical staining and western blotting.
Western blotting: 0.5-2µg/mL
Optimal working dilutions must be determined by end user.
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
|Cancer Chemotherapy and Pharmacology||Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells. PubMed: 19466611|
|European Journal of Pharmacology||Baicalin suppresses lung carcinoma and lung metastasis by SOD mimic and HIF-1α inhibition ScienceDirect: S0014299909011352|
|PLoS ONE||Lactate Dehydrogenase 5 Expression in Non-Hodgkin Lymphoma Is Associated with the Induced Hypoxia Regulated Protein and Poor Prognosis PubMed: PMC3781153|
|International Journal of Molecular Medicine||Selective inhibition of PKCβ2 preserves cardiac function after myocardial infarction and is associated with improved angiogenesis of ischemic myocardium in diabetic rats Pubmed: 24002353|
|Canadian Journal of Physiology and Pharmacology||Modulation of arginine and asymmetric dimethylarginine concentrations in liver and plasma by exogenous hydrogen sulfide in LPS-induced endotoxemia Pubmed: 24289078|
|US8569372 B2||Method for preventing or treating a disease, disorder or condition induced by retina ischemia US8569372|
|J Surg Res.||Effects of adrenomedullin and vascular endothelial growth factor on ischemia/reperfusion injury in skeletal muscle in rats. Pubmed: 23816242|
|PLoS One.||HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis Plos: Source|
|Journal of Physiological Anthropology||Telomeres are elongated in rats exposed to moderate altitude Pubmed:Pmc4088304|
|Molecular Medicine Reports||Resveratrol abrogates the effects of hypoxia on cell proliferation, invasion and EMT in osteosarcoma cells through downregulation of the HIF-1α protein. Pubmed:25384583|
|International Journal of Pharmaceutics||The enhancement of gene silencing efficiency with chitosan-coated liposome formulations of siRNAs targeting HIF-1α and VEGF Pubmed:25445537|
|International Journal of Molecular Medicine||Effect of combined treatment with rosuvastatin and protein kinase Cβ2 inhibitor on angiogenesis following myocardial infarction in diabetic rats Pubmed:25524396|
|International Journal of Developmental Neuroscience||Maternal omega-3 fatty acid supplementation to a vitamin B 12 deficient diet normalizes angiogenic markers in the pup brain at birth PubMed: 25889224|
|Eur Surg Res||Determination of the Preferred Conditions for the Isolated Perfusion of Porcine Kidneys PubMed: 25341590|
|Sci Rep||Oxygen-induced cell migration and on-line monitoring biomarkers modulation of cervical cancers on a microfluidic system PubMed: 25905434|
|Evidence-Based Complementary and Alternative Medicine||Metabolomic Analysis of Biochemical Changes in the Plasma of High-Fat Diet and Streptozotocin-Induced Diabetic Rats after Treatment with Isoflavones Extract of Radix Puerariae pmc:PMC4794592|
|Biol Trace Elem Res.||Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α Pubmed:27121973|
|Раны и раневые инфекции.||Использование гипоксического прекондиционирования для подготовки аутодермотрансплантата у больных со скомпрометированной микроциркуляцией 91|
|Biological Trace Element Research||Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α. pubmed:27121973|
|Experimental and Therapeutic Medicine||Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis etm:13|
|Catalog No.||Related products for research use of Rattus norvegicus (Rat) Organism species||Applications (RESEARCH USE ONLY!)|
|RPA798Ra01||Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a)||Positive Control; Immunogen; SDS-PAGE; WB.|
|RPA798Ra02||Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a)||Positive Control; Immunogen; SDS-PAGE; WB.|
|PAA798Ra01||Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a)||WB; IHC; ICC; IP.|
|PAA798Ra02||Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a)||WB; IHC; ICC; IP.|
|LAA798Ra71||Biotin-Linked Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a)||WB; IHC; ICC.|
|SEA798Ra||ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a)||Enzyme-linked immunosorbent assay for Antigen Detection.|
|SCA798Ra||CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a)||Chemiluminescent immunoassay for Antigen Detection.|