Monoclonal Antibody to Mannose Associated Serine Protease 1 (MASP1)

CRARF; PRSS5; Mannan-Binding Lectin Serine Peptidase 1; Ra-reactive factor serine protease p100; Complement-activating component of Ra-reactive factor; Serine protease 5

  • Product No.MAB895Hu22
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 106  US$ 246  US$ 352  US$ 880  US$ 3520 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against MASP1. It has been selected for its ability to recognize MASP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Pathology Increased Circulating Plasma Mannose Binding Lectin Associated Serine Protease (Masp) As A Result of Enu-Induced Mutation in Masp-1 Lww: Source
The Journal fo Biological Chemistry Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype Pubmed:24550392
the journal of immunology The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema PubMed: 26371246
J Neuroinflammation.  Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis PMC5234106
Frontiers in Immunology AmpliSeq screening of genes encoding the C-type lectin receptors and their signaling components reveals a common variant in MASP1 associated with … Pubmed:29515573
Journal of Proteomics Plasma proteome profiling of high-altitude polycythemia using TMT-based quantitative proteomics approach Pubmed: 30605725
Kidney International Reports Clinical value of complement activation biomarkers in overt diabetic nephropathy
Kidney International Reports Comparison of Complement Pathway Activation in Autoimmune Glomerulonephritis Pubmed:35571000
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB895Hu01 Recombinant Mannose Associated Serine Protease 1 (MASP1) Positive Control; Immunogen; SDS-PAGE; WB.
PAB895Hu01 Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB,IHC
MAB895Hu22 Monoclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB; IHC; ICC; IP.
SEB895Hu ELISA Kit for Mannose Associated Serine Protease 1 (MASP1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB895Hu Multiplex Assay Kit for Mannose Associated Serine Protease 1 (MASP1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.