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Monoclonal Antibody to Transforming Growth Factor Beta Receptor I (TGFbR1)

ACVRLK4; AAT5; ALK5; SKR4; TGFR-1; Activin A Receptor Type II-Like Kinase 53kDa; Activin receptor-like kinase 5; Serine/threonine-protein kinase receptor R4

  • Product No.MAA397Hu22
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 101  US$ 235  US$ 336  US$ 840  US$ 3360 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against TGFbR1. It has been selected for its ability to recognize TGFbR1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Biochem Pharmacol. Gallium, a promising candidate to disrupt the vicious cycle driving osteolytic metastases. pubmed:27378505
Scientific Reports TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease. pubmed:27549738
The Journal of Clinical Endocrinology & Metabolism Multiple soluble TGF-β receptors in addition to soluble endoglin are elevated in preeclamptic serum and they synergistically inhibit TGF-β signalling 10.1210/jc.2017-01150
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA397Hu01 Recombinant Transforming Growth Factor Beta Receptor I (TGFbR1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA397Hu01 Polyclonal Antibody to Transforming Growth Factor Beta Receptor I (TGFbR1) WB; IHC; ICC; IP.
MAA397Hu22 Monoclonal Antibody to Transforming Growth Factor Beta Receptor I (TGFbR1) WB; IHC; ICC; IP.
SEA397Hu ELISA Kit for Transforming Growth Factor Beta Receptor I (TGFbR1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA397Hu Multiplex Assay Kit for Transforming Growth Factor Beta Receptor I (TGFbR1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.