Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)

DIF; TNF-A; TNFSF2; Cachectin; Tumor Necrosis Factor Ligand Superfamily Member 2

SPECIFITY

The antibody is a mouse monoclonal antibody raised against TNFa. It has been selected for its ability to recognize TNFa in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;1:450-1700
Immunohistochemistry: 5-20µg/mL;1:45-170
Immunocytochemistry: 5-20µg/mL;1:45-170
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
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Swimming training attenuates the morphological reorganization of the myocardium and local inflammation in the left ventricle of growing rats with untreated experimental diabetes. Pubmed:26896925
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Clin Epigenetics. The bromodomain inhibitor N-methyl pyrrolidone reduced fat accumulation in an ovariectomized rat model Pubmed:27110299
Int J Mol Sci. Dexmedetomidine Protects Rat Liver against Ischemia-Reperfusion Injury Partly by the α2A-Adrenoceptor Subtype and the Mechanism Is Associated with the TLR4/NF-κB Pathway Pubmed:27347929
Journal of Neuroinflammation Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats pubmed:27716383
Journal of traditional and complementary medicine. Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats. pubmed:27774414
Front Pharmacol Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata pubmed:27803670
BMC Veterinary Research Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis pubmed:27553600
Oxidative Medicine and Cellular Longevity Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation. pubmed:27656261
Journal of Pre-Clinical and Clinical Research Circulating cytokeratin-18 and tumour necrosis factor-α in patients with alcoholic liver cirrhosis 582a2e2208aef19cb8053ce8.pdf
BMC Complementary and Alternative Medicine Effect of traditional Chinese medicine formula Sinisan on chronic restraint stress-induced nonalcoholic fatty liver disease: a rat study. pubmed:28388904
immunology letters Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila. pubmed:28366526
IUBMB Life. Elevated serum milk fat globule-epidermal growth factor 8 levels in type 2 diabetic patients are suppressed by overweight or obese status. pubmed:28067023
Scientific Reports Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis. pubmed:28272440
Lipids in Health and Disease Protective effects of various ratios of DHA/EPA supplementation on high-fat diet-induced liver damage in mice. pubmed:28356106
Journal of Functional Foods Eicosapentaenoic acid-enriched phospholipids improve atherosclerosis by mediating cholesterol metabolism S1756464617300890
biomedicine & pharmacotherapy Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation. pubmed:28033582
Nutrition. Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats. pubmed:27908549
Journal of diabetes investigation Circulating milk fat globule-epidermal growth factor 8 levels are increased in pregnancy and gestational diabetes mellitus. pubmed:28035763
International Journal of Molecular Medicine The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats pubmed:27430552
未查到 Clinical effect of electro-acupuncture on lung injury patients caused by severe 3162851.pdf
Journal of Molecular and Cellular Cardiology Irisin improves perivascular adipose tissue dysfunction via regulation of the heme oxygenase-1/adiponectin axis in diet-induced obese mice pubmed:27638193
Springerplus Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway pubmed:27026909
Andrology Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis … doi:10.1111
Cellular Physiology and Biochemistry The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. pubmed:27576607
Journal of Orthopaedic Surgery and Research  No midterm advantages in the middle term using small intestinal submucosa and human amniotic membrane in Achilles tendon transverse tenotomy pubmed:27881176
Atherosclerosis Iridoid–loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs … S0021915016314046
International Journal of Clinical and Experimental Pathology Level of serum apolipoprotein m and its diagnostic significance in inflammatory bowel disease files:ijcep0033416.pdf
Molecular Medicine Reports C‑reactive protein/oxidized low density lipoprotein/β2‑glycoprotein i complexes induce lipid accumulation and inflammatory reaction in macrophages via p38/mitogen‑ … 10.3892
Physiological Research Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. pubmed:28006947
Molecular Medicine Reports Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects pubmed:27432278
The American Journal of Chinese Medicine Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after InhaledCorticosteroid Withdrawal in COPD Rats. pubmed:27430907
Cardiovascular Diabetology Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. pubmed:27809851
PLOS ONE Protective Effects of Bifidobacterium on Intestinal Barrier Function in LPS-Induced EnterocyteBarrier Injury of Caco-2 Monolayers and in a Rat NEC Model. pubmed:27551722
Food & Function Protective effects of fish oil on pre-diabetes: a lipidomic analysis of liver ceramides in rats. pubmed:27722538
PLOS ONE Mechanical Ventilation Alters the Development of Staphylococcus aureus Pneumonia in Rabbit. pubmed:27391952
The Journal of Comenius University in Bratislava Effects of Conventional Mechanical Ventilation Performed by Two Neonatal Ventilators on the Lung Functions of Rabbits with Meconium-Induced Acute Lung Injury acm.2017.16.issue-3
Journal of Physiology and Pharmacology Effects of budesonide on the lung functions, inflammation and apoptosis in a saline-lavagemodel of acute lung injury. pubmed:28195073
Applied Biochemistry and Biotechnology Protective Effect of Zingiber officinale Against Dalton's Lymphoma Ascites Tumour byRegulating Inflammatory Mediator and Cytokines. pubmed:27435276
Future Microbiology Transplantation of a bacterial consortium ameliorates trinitrobenzenesulfonic acid-induced colitisand intestinal dysbiosis in rats. pubmed:27415182
BioMed Research International Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced DiabeticMice. pubmed:28421194
Saudi Journal of Gastroenterology Deoxyschizandrin suppresses dss-induced ulcerative colitis in mice. pubmed:27976641
Parasites & Vectors Vaccination of rabbits with immunodominant antigens from Sarcoptes scabiei induced highlevels of humoral responses and pro-inflammatory cytokines but confers limited protection. pubmed:27502394
中国药物警戒 小剂量阿奇霉素对稳定期老年慢性阻塞性肺疾病患者外周血内TNF-α、IL-8、CRP水平及肺功能的影响 Periodical_zgywjj201608004
Oncotarget Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation andapoptosis in diabetic cardiomyopathy. pubmed:27027354
Life Sciences Bone fracture healing is delayed in splenectomic rats pubmed:27956350
Journal of Ethnopharmacology Learning and memory improvement and neuroprotection of Gardenia jasminoides (Fructusgardenia) extract on ischemic brain injury rats. pubmed:27940085
Journal of Cancer Research and Treatment Effect of Indole-3-carbinol and/or Metformin on Female Patients with Ulcerative Colitis (Premalignant Condition): Role of Oxidative Stress, Apoptosis and Proinflammatory Cytokines jcrt:5
Food Funct. Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through the MAPK and NF-κB pathways. pubmed:28256654
 Research in Veterinary The effect of feed supplementation with zinc chelate and zinc sulphate on selected humoral and cell-mediated immune parameters and cytokine concentration in … S0034528816303162
Mol Med Rep. Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension. pubmed:27959409
Parasitology. Nonsteroidal anti-inflammatory is more effective than anti-oxidant therapy in counteracting oxidative/nitrosative stress and heart disease in T. cruzi-infected mice. pubmed:28134069
Ren Fail.  Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats. pubmed:27841100
PLoS One. Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders. pubmed:28207788
Sci Rep.  Comparison of human adipose stromal vascular fraction and adipose-derived mesenchymal stem cells for the attenuation of acute renal ischemia/reperfusion injury. pubmed:28276451
Cell Death Dis. Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy pubmed:28333148
Journal of Photochemistry and Photobiology B: Biology Efficacy of scaling and root planning with and without adjunct Nd:YAG laser therapy on clinical periodontal parameters and gingival crevicular fluid interleukin 1-beta and tumor necrosis factor-alpha levels among patients with periodontal disease: A prospective randomized split-mouth clinical study. pubmed:28282558
Journal of Cellular Physiology Autophagy maintains the integrity of endothelial barrier in LPS-induced lung injury. pubmed:28328069
Key Engineering Materials The Level of Inflammatory Cytokines and Antimicrobial Peptides after Composite Material Implantation and Contamination with Bacterial Culture. 16629795
Biomedicine & pharmacotherapy= Biomedecine & pharmacotherapie Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion pubmed:28273631
IOS Press Content Library An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's … articles:journal-of-alzheimers-disease
Journal of Neurochemistry β‐Caryophyllene protects in vitro neurovascular unit against oxygen‐glucose deprivation and re‐oxygenation‐induced injury pubmed:27565895
Journal of Functional Foods Impact of purified oat 1-3, 1-4-β-d-glucan of different molecular weight on alleviation of inflammation parameters during gastritis S1756464616303528
International Journal of Stem Cell Research and Transplantation Protective Role of Bone Marrow Derived Mesenchymal Stem Cells-Conditioned Medium in the Infarcted Myocardium: The Potential Role of Selected Cytokines IJST-2328-3548-04-803
Домашня сторінка ВПЛИВ КРОВОВТРАТИ НА ДИНАМІКУ ВМІСТУ ЦИТОКІНІВ СИРОВАТКИ КРОВІ В ПЕРІОД ГОСТРОЇ РЕАКЦІЇ НА КРАНІОСКЕЛЕТНУ ТРАВМУ 83646
Journal of Agricultural and Food Chemistry Effect of boron on thymic cytokine expression, hormone secretion, antioxidant functions, cell proliferation, and apoptosis potential via the ERK1/2 signaling pathway pubmed:29032684
MOLECULAR MEDICINE REPORTS The effect of anagliptin on intimal hyperplasia of rat carotid artery after balloon injury pubmed:28990108
Clinical Effect of Electroacupuncture on Lung Injury Patients Caused by Severe Acute Pancreatitis Evidence-based Complementary and Alternative Medicine pubmed:28751922
Iranian Journal of Basic Medical Sciences Naringin attenuates diabetic retinopathy by inhibiting inflammation, oxidative stress and NF-κB activation in vivo and in vitro pubmed:28852447
Journal of Cellular Physiology Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Models pubmed:27739057
Toxicology and Applied Pharmacology Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454
Biomedicine & Pharmacotherapy Cytokine production in vitro and in rat model of colitis in response to Lactobacillus plantarum LS/07 pubmed:28830068
Scientific RepoRts The influence of liposomal quercetin on liver damage induced by microwave ablation pubmed:28978941
Research in Veterinary Science The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs pubmed:28549299
Food & Function Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264. 7 macrophages through the MAPK and NF-κB … DOI:10.1039/C6FO01873D
European Journal of Pharmacology Cardioprotective time-window of Penehyclidine hydrochloride postconditioning: A rat study pubmed:28684235
Brain, Behavior, and Immunity The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in mice pubmed:28483659
PLoS One Linezolid and atorvastatin impact on pneumonia caused by Staphyloccocus aureus in rabbits with or without mechanical ventilation pubmed:29149185
cellular physiology and biochemistry Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β … pubmed:29040978
Food & Function Sea cucumber saponins liposomes ameliorate obesity-induced inflammation and insulin resistance in high-fat diet-fed mice pubmed:29292463
Microbial Immunology Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota pubmed:28713364
Archives of Oral Biology The effect of restorative materials on cytokines in gingival crevicular fluid pubmed:28992599
Scientific Reports A Systems Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Xipayi KuiJie’an enema for Treatment of Ulcerative colitis doi:10.1038/s41598-017-01335-w
Journal of Animal Physiology and Animal Nutrition The effect of feed supplementation with a copper-glycine chelate and copper sulphate on selected humoral and cell-mediated immune parameters, plasma superoxide dismutase activity, ceruloplasmin and cytokine concentration in broiler chickens doi:10.1111
Frontiers in Neurology a-Asarone Attenuates Cognitive Deficit in a Pilocarpine-Induced Status Epilepticus Rat Model via a Decrease in the Nuclear Factor-觀B Activation and Reduction in Microglia Neuroinflammation. pubmed:29312110
中国免疫学杂志 b-caryophyllene mitigates cerebral ischemia reperfusion injury in mice by inhibiting HMGB1/ TLR4/ NFkB pathway doi:10. 3969 / j. issn. 1000-484X. 2017. 07. 011
clinical and experimental pharmacology and physiology C1q/TNF‐related protein 9 improves the anti‐contractile effects of perivascular adipose tissue via the AMPK‐eNOS pathway in diet‐induced obese mice pubmed:28902432
Chinese Journal of comparative medicine (中国比较医学杂志) 富氢液通过P13K通路减轻大鼠脑缺血再灌注损伤 doi:10u3969.j.issn.1671-7856
PLoS One Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders 10.1371:journal.pone.0172181
Oncotarget. Tumor-associated macrophages promote tumor metastasis via the TGF-β/SOX9 axis in non-small cell lung cancer pubmed:29245941
Scientific Reports Comparison of human adipose stromal vascular fraction and adipose-derived mesenchymal stem cells for the attenuation of acute renal ischemia/reperfusion injury PMC5343423
Molecular Neurobiology Decrease in Adult Neurogenesis and Neuroinflammation Are Involved in Spatial Memory Impairment in the Streptozotocin-Induced Model of Sporadic Alzheimer’s Disease in Rats article:10.1007
Oxidative Medicine and Cellular Longevity Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects pubmed:28798861
International Journal of Biological Macromolecules Chemical composition of Cyclocarya paliurus polysaccharide and inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophage pubmed:29032210
Drug Design Development and Therapy High-dose dexamethasone induced LPS-stimulated rat alveolar macrophages apoptosis. pubmed:29123381
Nutrition Administration of probiotic mixture DM#1 ameliorated 5-fluorouracil-induced intestinal mucositis and dysbiosis in rats pubmed:27427511
Current Eye Research Inhibition of Fusarium solani Infection in Murine Keratocytes by Lactobacillus salivarius ssp. salivarius JCM1231 Culture Filtrate In Vitro pubmed:28636459
PLOS Neglected Tropical Diseases An attenuated Shigella mutant lacking the RNA-binding protein Hfq provides cross-protection against Shigella strains of broad serotype pubmed:28727722
Frontiers in Neuroscience Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro PMC5662640
Biomedical Research Correlation between high mobility group box 1 protein, tumor necrosis factor-α, and acute coronary syndrome ISSN 0970-938X
Biological Trace Element Research Protective Effect of Origanum Oil on Alterations of Some Trace Elements and Antioxidant Levels Induced by Mercuric Chloride in Male Rats pubmed:28616770
International Journal of Biological Sciences Chronic Osteomyelitis Increases the Incidence of Type 2 Diabetes in Humans and Mice pubmed:29104510
International Journal of Clinical and Experimental Pathology Platelet-derived growth factor and stromal cell-derived factor-1 promote the skin wound repairing effect of bone mesenchymal stem cells: a key role of matrix metalloproteinase 1 and collagens ISSN:1936-2625/IJCEP0058424
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitis pubmed:29207044
Cellular Physiology and Biochemistry Dexmedetomidine Alleviates HyperoxiaInduced Acute Lung Injury via Inhibiting NLRP3 Inflammasome Activation pubmed:28873369
Acta Paediatrica Serum complement factor 5a levels are associated with nonalcoholic fatty liver disease in obese children DOI: 10.1111/apa.14106
Biomedicine & Pharmacotherapy Protective effect of Averrhoa bilimbi L. fruit extract on ulcerative colitis in wistar rats via regulation of inflammatory mediators and cytokines pubmed:28531922
Molecular Medicine Reports Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury 10.3892/mmr.2017.6837
International Journal of Clinical and Experimental Pathology Bone marrow-derived mesenchymal stem cells alleviates renal injury in severe acute pancreatitis via RhoA/Rho kinase ISSN:1936-2625
Tropical Journal of Pharmaceutical Research Protective effect of salvianolic acid B against intestinal ischemia reperfusion-induced injury in a rat model 10.4314/tjpr.v16i10.17
International Journal of Clinical and Experimental Pathology Protective effect of high mobility group box-1 silence on diabetic retinopathy: an in vivo study ISSN:1936-2625/IJCEP0055881
Pharmacology Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats pubmed:28637971
Oncotarget The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis. pubmed:29029533
Frontiers in Molecular Neuroscience Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats 10.3389/fnmol.2017.00363
Oncotarget Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response. pubmed:28489606
Tissue Engineering. Part C, Methods Short-Term Homing of Hyaluronan-Primed Cells: Therapeutic Implications for Osteoarthritis Treatment pubmed:29108480
Oncotarget Global gene expression profile of cerebral ischemia-reperfusion injury in rat MCAO model pubmed:29088811
Oncotarget Neuroprotection of Botch in experimental intracerebral hemorrhage in rats. pubmed:29221132
Nature Medicine An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. pubmed:29227475
Journal of Ultrasound in Medicine Inhibitory Effect of Low-Intensity Pulsed Ultrasound on the Expression of Lipopolysaccharide-Induced Inflammatory Factors in U937 Cells. pubmed:28600899
International Immunopharmacology Therapeutic effect of bone marrow mesenchymal stem cells pretreated with acetylsalicylic acid on experimental periodontitis in rats pubmed:29195233
PLoS One Protective effect of aplysin on liver tissue and the gut microbiota in alcohol-fed rats pubmed:28622357
Nutrients Effect of Green and Brown Propolis Extracts on the Expression Levels of microRNAs, mRNAs and Proteins, Related to Oxidative Stress and Inflammation. pubmed:28974022
American journal of clinical and experimental immunology Effects of peritoneal macrophage autophagy on the immune function of sepsis mice. pubmed:28695057
Inflammation Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20. pubmed:28744711
Biomedical and Environmental Sciences Grape Seed Procyanidin Extract Reduces Arsenic-Induced Renal Inflammatory Injury in Male Mice. pubmed:28756814
Arthritis Research and Therapy Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis. pubmed:29191221
Journal of contemporary medical sciences Attenuation of acute systemic inflammatory response after valve surgery ISSN: 1556-4002
Journal of Pain Research Sex differences in complex regional pain syndrome type I (CRPS-I) in mice pubmed:28831269
Acta Pharmacologica Sinica Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ. pubmed:28649126
Toxicology Biological effects of adipocytes in sulfur mustard induced toxicity pubmed:29129815
Molecular Medicine Reports Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway pubmed:28944825
Veterinary microbiology Secondary Haemophilus parasuis infection enhances highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection-mediated inflammatory responses. pubmed:28532803
Evidence-based complementary and alternative medicine Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats pubmed:28706558
Frontiers in Molecular Neuroscience Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. pubmed:28959186
In Vivo Study on the Hindrance Activity of Cinnamon Extract Against Aspergillus niger in Mice ISSN: 0974-4290
Clinical Cancer Research Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration Pubmed:30012567
Critical Care Medicine Treatment of Paraquat-Induced Lung Injury With an Anti-C5a Antibody: Potential Clinical Application Pubmed:29293144
Cell Death & Disease AMP-activated protein kinase agonist N 6-(3-hydroxyphenyl) adenosine protects against fulminant hepatitis by suppressing inflammation and apoptosis Articles:s41419-017-0118-0
Journal of Molecular Cell Biology S1 PR 3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen‐glucose deprivation‐induced neuroinflammation via inhibiting TLR 2/4‐NF κB … Pubmed:29536648
Cellular Physiology and Biochemistry Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory … Pubmed:29672286
Clinical Science Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity Pubmed:29382697
Molecular Nutrition & Food Research The Protective Activities of Dietary Sea Cucumber Cerebrosides Against Atherosclerosis Through Regulating Inflammation and Cholesterol Metabolism in Male Mice Pubmed:29883529
Molecular Neurobiology Decrease in adult neurogenesis and neuroinflammation are involved in spatial memory impairment in the streptozotocin-induced model of sporadic Alzheimer's … Pubmed:28623617
Molecular Neurobiology Neuroprotective Effects of Filgrastim in Rotenone-Induced Parkinson's Disease in Rats: Insights into its Anti-Inflammatory, Neurotrophic, and Antiapoptotic Effects s12035-017-0855-1
Stem Cell Research & Therapy The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity Pubmed:30021657
Environmental Pollution Exposure to environmental level phenanthrene induces a NASH-like phenotype in new born rat Pubmed:29656250
Neuropharmacology Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway Pubmed:29518397
Scientific Reports A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling Pubmed:29523851
American Journal of Physiology-Lung Cellular and Molecular Physiology Maternal PUFA omega-3 supplementation prevents hyperoxia-induced pulmonary hypertension in the offspring Pubmed:29597832
Journal of Clinical Periodontology  Peroxisome proliferator‐activated receptor γ plays dual roles on experimental periodontitis in rats Pubmed:29574908
Food and Chemical Toxicology Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats Pubmed:30026088
Mechanisms of Ageing and Development Multivessel analysis of progressive vascular aging in the rat: Asynchronous vulnerability among vascular territories Pubmed:29605639
International Journal of Molecular Sciences Screening of circular RNAs and validation of circANKRD36 associated with inflammation in patients with type 2 diabetes mellitus Pubmed:30066828
British journal of nutrition Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1, 2-dimethylhydrazine-induced rat colorectal … Pubmed:29947321
Frontiers in Endocrinology Circulating and Adipose Tissue mRNA Levels of Zinc-α2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in … Pubmed:29755407
Frontiers in Neurology Ursolic Acid Ameliorates Inflammation in Cerebral Ischemia and Reperfusion Injury Possibly via High Mobility Group Box 1/Toll-Like Receptor 4/NFκB … Pubmed:29867706
Journal of Functional Foods Dietary functional flavonoids as natural hepatoprotective agents against acute liver injury from hop ( L.) 10.1016:j.jff.2018.04.042
Journal of Functional Foods Hepatoprotective effect of flavonoid-enriched fraction from Cyclocarya paliurus leaves on LPS/D-GalN-induced acute liver failure 10.1016:j.jff.2018.07.031
Journal of Functional Foods Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties 10.1016:j.jff.2018.07.046
Molecular Brain Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats Pubmed:29439730
Neuroscience Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats Pubmed:29684507
Inflammopharmacology Protective effect of isoliquiritigenin against cerebral injury in septic mice via attenuation of NF-κB Pubmed:29943151
Inflammopharmacology Polar extract of protects cartilage homeostasis: possible mechanism of action Pubmed:29313174
Chemico-Biological Interactions Nifuroxazide, a STAT3 inhibitor, mitigates inflammatory burden and protects against diabetes-induced nephropathy in rats Pubmed:29291386
Food & Function Calycosin directly improves perivascular adipose tissue dysfunction by upregulating the adiponectin/AMPK/eNOS pathway in obese mice Pubmed:29595858
Food & Function Asiatic acid suppresses neuroinflammation in BV2 microglia via modulation of the Sirt1/NF-κB signaling pathway Pubmed:29354820
Life Sciences Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation Pubmed:29499280
Life Sciences Alamandine attenuates sepsis-associated cardiac dysfunction via inhibiting MAPKs signaling pathways Pubmed:29679702
Parkinsons Disease Apolipoprotein D Concentration in Human Plasma during Aging and in Parkinson's Disease: A Cross-Sectional Study Pubmed:29780571
Brain Research Intra-arterial human urinary kallidinogenase alleviates brain injury in rats with permanent middle cerebral artery occlusion through PI3K/AKT/FoxO1 signaling pathway Pubmed:29510144
International Immunopharmacology The effect of natural antioxidants in cyclophosphamide-induced hepatotoxicity: Role of Nrf2/HO-1 pathway Pubmed:29800788
Free Radical Research Lycium barbarum polysaccharide protects against LPS-induced ARDS by inhibiting apoptosis, oxidative stress, and inflammation in pulmonary endothelial cells Pubmed:29502482
International Endodontic Journal Inhibition of SOX9 Promotes Inflammatory and Immune Responses of Dental Pulp Pubmed:29571909
Bioscience Reports Effect of maternal hypothyroidism during pregnancy on insulin resistance, lipid accumulation and mitochondrial dysfunction in skeletal muscle of fetal rats Pubmed:29784871
International Journal of Molecular Medicine Aspirin modulates the inflammatory response in a thrombus‑stimulated LMVEC model Pubmed:29568915
Neurochemical Research E3 Ubiquitin Ligase c-cbl Inhibits Microglia Activation After Chronic Constriction Injury Pubmed:29934689
PLoS One Chitosan oligosaccharide ameliorates acute lung injury induced by blast injury through the DDAH1/ADMA pathway Pubmed:29415054
Biochemical and Biophysical Research Communications PPARγ alleviated hepatocyte steatosis through reducing SOCS3 by inhibiting JAK2/STAT3 pathway Pubmed:29550470
Journal of Molecular Neuroscience A Novel scFv Anti-Aβ Antibody Reduces Pathological Impairments in APP/PS1 Transgenic Mice via Modulation of Inflammatory Cytokines and Aβ-related Enzymes Pubmed:30062438
International Immunopharmacology  Tn (-acetyl-d-galactosamine--serine/threonine) immunization protects against hyperoxia-induced lung injury in adult mice through inhibition of the nuclear factor … Pubmed:29669308
Experimental biology and medicine (Maywood) Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse model Pubmed:29984607
Probiotics Antimicrob Proteins Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a … Pubmed:29305686
International Journal of Endocrinology Uncoupling Protein 2 and Peroxisome Proliferator-Activated Receptor γ Gene Polymorphisms in Association with Diabetes Susceptibility in Chinese Han Population … Pubmed:29849618
Microbial Pathogenesis Pathogen-dependent modulation of milk neutrophils competence, plasma inflammatory cytokines and milk quality during intramammary infection of Sahiwal (Bos … Pubmed:29787791
Innate Immunity  Lipoxin A attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis Pubmed:29969931
Archives of Virology MAVS induces a host cell defense to inhibit CSFV infection Pubmed:29556776
Archives of Virology Genetic and immunogenicity analysis of porcine circovirus type 2 strains isolated in central China Pubmed:29305646
Clinical And Experimental Pharmacology And Physiology  Diallyl sulfide alleviates cisplatin‐induced nephrotoxicity in rats via suppressing NF‐κB downstream inflammatory proteins and p53/Puma signalling pathway Pubmed:29266336
Evidence-Based Complementary and Alternative Medicine Tualang Honey Reduced Neuroinflammation and Caspase-3 Activity in Rat Brain after Kainic Acid-Induced Status Epilepticus Pubmed:30108663
Molecular Medicine Reports Protective effects of N (2)‑L‑alanyl‑L‑glutamine mediated by the JAK2/STAT3 signaling pathway on myocardial ischemia reperfusion Pubmed:29393473
Molecular Medicine Reports  Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats Pubmed:29956781
Molecular Medicine Reports Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway Pubmed:29620209
Molecular Medicine Reports Effects of GGCX overexpression on anterior cruciate ligament transection-induced osteoarthritis in rabbits Pubmed:29257344
Medical Science Monitor Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4) … Pubmed:29804125
Medical Science Monitor Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats Pubmed:29290631
Medical Science Monitor Sulforaphane, a Natural Isothiocyanate Compound, Improves Cardiac Function and Remodeling by Inhibiting Oxidative Stress and Inflammation in a Rabbit … Pubmed:29527002
Human and Experimental Toxicology Neuroprotective effect of agmatine (decarboxylated -arginine) against oxidative stress and neuroinflammation in rotenone model of Parkinson's disease Pubmed:30001633
International Urology and Nephrology Mesenchymal stem cells alleviate acute kidney injury by down-regulating C5a/C5aR pathway activation Pubmed:29594894
Oncology Letters Hydrogen‑rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus‑activated kinase 2/signal transducer and activator of … Pubmed:29928398
Journal of Animal Physiology and Animal Nutrition The effect of feed supplementation with a copper‐glycine chelate and copper sulphate on selected humoral and cell‐mediated immune parameters, plasma … Pubmed:28603872
Journal of Maternal-Fetal & Neonatal Medicine Amniotic fluid HIF1α and exosomal HIF1α in cervical insufficiency patients with physical examination-indicated cerclage Pubmed:29357727
Reproductive Biology Anti-hypercholesterolemic impacts of barley and date palm fruits on the ovary of Wistar albino rats and their offspring Pubmed:30005909
Experimental and Therapeutic Medicine S‑adenosyl methionine regulates calcium channels and inhibits uterine smooth muscle contraction in rats with infectious premature delivery through the transient … Pubmed:29896230
International Journal of Environmental Studies  Effectiveness of steamed and cooked broccoli to attenuate bone marrow injury and suppressed haemopoiesis in male rats exposed to petrol vapours 10.1080:00207233.2018.1502956
International Journal of Clinical and Experimental Medicine BoNT-A attenuated pain of endometriosis by inhibiting microglia activation files:ijcem0055240.pdf
International Journal of Pharmacology Evaluation of Susceptibility and Innate Immune Response to Candida albicans in Mice with Sub-health ijp.2018.689.697
International Journal of Clinical and Experimental Medicine Improvement effect of doxofylline on the mechanism of glucocorticoid resistance in chronic obstructive pulmonary disease rat model ijcem0067841.pdf
Journal of Cellular Biochemistry Uroprotective mechanism of quercetin against cyclophosphamide‐induced urotoxicity: Effect on oxidative stress and inflammatory markers Pubmed:29775228
Catalog No. Related products for research use of Ovis aries; Ovine (Sheep) Organism species Applications (RESEARCH USE ONLY!)
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KSA133Ov01 ELISA Kit DIY Materials for Tumor Necrosis Factor Alpha (TNFa) Main materials for "Do It (ELISA Kit) Yourself".