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Mouse Model for Melasma

Chloasma faciei; Yellow Speckle

  • Product No.DSI750Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by injection of progesterone combined with ultraviolet irradiation
  • Model Animal StrainsKunming (KM) mice, female, body weight: about 30g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period6~8 weeks
  • Modeling Method10% sodium sulfide aqueous solution to remove the back of the mouse hair, naked skin area of 1.5cmx1.5cm. Daily intramuscular injection of 0.4% progesterone (5ml/Kg body weight);
    at the same time with a wavelength of 320nm in the ultraviolet (UVB) irradiation for a period of 6~8 weeks.
  • ApplicationsDisease Model
  • Downloadn/a
  • UOM Each case
  • FOB US$ 240 
    For more details, please contact local distributors!

Model Evaluation

1. The pathological morphology of skin melanocytes
2. MDA and SOD activity assay
3. Detection of behavior experiment:Open field test and Tail flick test

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
DSI750Mu01 Mouse Model for Melasma Disease Model