Fibrinogen Like Protein 1 (FGL1)
[Edit]FGL-1; HFREP1; HP-041; LFIRE1; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; Liver fibrinogen-related protein 1
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Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. The deduced 312-amino acid FGL1 protein possesses a hydrophobic leader peptide. FGL1 shares significant sequence homology with FGB and FGG and with other fibrinogen-related proteins. The FGL1 sequence includes 4 cysteine residues that are widely conserved in all fibrinogens and fibrinogen-related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD022Mu01 | Recombinant Fibrinogen Like Protein 1 (FGL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPD022Mu02 | Recombinant Fibrinogen Like Protein 1 (FGL1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAD022Mu01 | Polyclonal Antibody to Fibrinogen Like Protein 1 (FGL1) | WB; IHC; ICC; IP. |
| LAD022Mu71 | Biotin-Linked Polyclonal Antibody to Fibrinogen Like Protein 1 (FGL1) | WB; IHC; ICC. | |
| PAD022Mu02 | Polyclonal Antibody to Fibrinogen Like Protein 1 (FGL1) | WB; IHC; ICC; IP. | |
| Assay Kits | SED022Mu | ELISA Kit for Fibrinogen Like Protein 1 (FGL1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD022Ra01 | Recombinant Fibrinogen Like Protein 1 (FGL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPD022Ra02 | Recombinant Fibrinogen Like Protein 1 (FGL1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAD022Ra01 | Polyclonal Antibody to Fibrinogen Like Protein 1 (FGL1) | WB; IHC; ICC; IP. |
| Assay Kits | SED022Ra | ELISA Kit for Fibrinogen Like Protein 1 (FGL1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD022Bo01 | Recombinant Fibrinogen Like Protein 1 (FGL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAD022Bo01 | Polyclonal Antibody to Fibrinogen Like Protein 1 (FGL1) | WB; IHC; ICC; IP. |
| LAD022Bo71 | Biotin-Linked Polyclonal Antibody to Fibrinogen Like Protein 1 (FGL1) | WB; IHC; ICC. | |
| Assay Kits | n/a | CLIA Kit for Fibrinogen Like Protein 1 (FGL1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibrinogen Like Protein 1 (FGL1) | ELISA Kit Customized Service Offer |
- "Molecular cloning and initial characterization of a novel fibrinogen-related gene, HFREP-1."Biochem. Biophys. Res. Commun. 193:681-687(1993) [PubMed] [Europe PMC] [Abstract]
- "Molecular cloning and functional expression analysis of a cDNA for human hepassocin, a liver-specific protein with hepatocyte mitogenic activity."Biochim. Biophys. Acta 1520:45-53(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]