Adrenomedullin (ADM)

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AM; PAMP; Proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide

Adrenomedullin (ADM)

Adrenomedullin (ADM) is a peptide associated with pheochromocytoma. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma. Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. The human AM gene is localized to a single locus on Chromosome 11 with 4 exons and 3 introns.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Hu01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
CPA220Hu31 KLH Conjugated Adrenomedullin (ADM) Immunogen; SDS-PAGE; WB.
CPA220Hu21 OVA Conjugated Adrenomedullin (ADM) Immunogen; SDS-PAGE; WB.
CPA220Hu32 KLH Conjugated Adrenomedullin (ADM) Immunogen; SDS-PAGE; WB.
Antibodies PAA220Hu01 Polyclonal Antibody to Adrenomedullin (ADM) WB; ICC; IHC-P; IHC-F; ELISA.
MAA220Hu22 Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
LAA220Hu71 Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC.
LAA220Hu81 FITC-Linked Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IF.
PAA220Hu08 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
PAA220Hu09 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
LAA220Hu72 Biotin-Linked Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC.
LAA220Hu82 FITC-Linked Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IF.
Assay Kits CEA220Hu ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Mu01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
RPA220Mu02 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA220Mu01 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
PAA220Mu02 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
Assay Kits CEA220Mu ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Ra01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
RPA220Ra02 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA220Ra01 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
PAA220Ra02 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
LAA220Ra71 Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC.
Assay Kits SEA220Ra ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA220Ra ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Ca01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA220Ca01 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
LAA220Ca71 Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC.
MAA220Ca21 Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
Assay Kits CEA220Ca ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Po01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA220Po01 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
MAA220Po21 Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
Assay Kits CEA220Po ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Bo01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA220Bo01 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
LAA220Bo71 Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC.
MAA220Bo21 Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
LAA220Bo81 FITC-Linked Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IF.
Assay Kits SEA220Bo ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA220Eq01 Recombinant Adrenomedullin (ADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA220Eq01 Polyclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
MAA220Eq21 Monoclonal Antibody to Adrenomedullin (ADM) WB; IHC; ICC; IP.
Assay Kits CEA220Eq ELISA Kit for Adrenomedullin (ADM) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning and characterization of cDNA encoding a precursor for human adrenomedullin."Biochem. Biophys. Res. Commun. 194:720-725(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic structure of human adrenomedullin gene."Biochem. Biophys. Res. Commun. 203:631-639(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma."Biochem. Biophys. Res. Commun. 192:553-560(1993) [PubMed] [Europe PMC] [Abstract]
  6. "Proadrenomedullin-derived peptides."Front. Neuroendocrinol. 19:100-127(1998) [PubMed] [Europe PMC] [Abstract]
  7. "Structure-activity relationships of adrenomedullin in the circulation and adrenal gland."Regul. Pept. 85:1-8(1999) [PubMed] [Europe PMC] [Abstract]
  8. "NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth."Biopolymers 81:295-308(2006) [PubMed] [Europe PMC] [Abstract]