Adrenomedullin (ADM)
[Edit]AM; PAMP; Proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide
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Adrenomedullin (ADM) is a peptide associated with pheochromocytoma. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma. Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. The human AM gene is localized to a single locus on Chromosome 11 with 4 exons and 3 introns.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA220Mu01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA220Mu02 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA220Mu01 | Active Adrenomedullin (ADM) | Cell culture; Activity Assays. | |
| Antibodies | PAA220Mu01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAA220Mu02 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA220Mu | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA220Ra01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA220Ra02 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA220Ra01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| PAA220Ra02 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. | |
| LAA220Ra71 | Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC. | |
| Assay Kits | SEA220Ra | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| CEA220Ra | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA220Ca01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA220Ca01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| LAA220Ca71 | Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC. | |
| MAA220Ca21 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA220Ca | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA220Po01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA220Po01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| MAA220Po21 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA220Po | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA220Bo01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA220Bo01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| LAA220Bo71 | Biotin-Linked Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC. | |
| MAA220Bo21 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. | |
| LAA220Bo81 | FITC-Linked Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IF. | |
| Assay Kits | SEA220Bo | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Equus caballus; Equine (Horse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA220Eq01 | Recombinant Adrenomedullin (ADM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA220Eq01 | Polyclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. |
| MAA220Eq21 | Monoclonal Antibody to Adrenomedullin (ADM) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA220Eq | ELISA Kit for Adrenomedullin (ADM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Cloning and characterization of cDNA encoding a precursor for human adrenomedullin."Biochem. Biophys. Res. Commun. 194:720-725(1993) [PubMed] [Europe PMC] [Abstract]
- "Genomic structure of human adrenomedullin gene."Biochem. Biophys. Res. Commun. 203:631-639(1994) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma."Biochem. Biophys. Res. Commun. 192:553-560(1993) [PubMed] [Europe PMC] [Abstract]
- "Proadrenomedullin-derived peptides."Front. Neuroendocrinol. 19:100-127(1998) [PubMed] [Europe PMC] [Abstract]
- "Structure-activity relationships of adrenomedullin in the circulation and adrenal gland."Regul. Pept. 85:1-8(1999) [PubMed] [Europe PMC] [Abstract]
- "NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth."Biopolymers 81:295-308(2006) [PubMed] [Europe PMC] [Abstract]