Matrix Metalloproteinase 3 (MMP3)

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SL1; STMY; STMY1; STR1; Progelatinase; Stromelysin 1; Transin-1

Matrix Metalloproteinase 3 (MMP3)

MMP-3 is secreted from the cells as a proenzyme. The proenzyme has been shown to stimulate plasminogen activation. The N-terminal pro-domain contains the cysteine switch motif conserved in MMPs that maintains MMP-3 in the latent state. Activation of the proenzyme results in the removal of the pro-domain. MMP-3 activation can be achieved in vitro by proteases such as itself, chyrotrypsin, neutrophil elastase and plasma kallikrein, and by mercury compounds.

The resulting active enzyme consists of a catalytic domain with a zinc-binding motif conserved in metzincins. A short hinge peptide links the catalytic domain to the C-terminal hemopexin-like domain. The active MMP-3 is capable of cleaving types III, IV, IX and X collagen, aggrecan, fibronectin, laminin, IGFBP-3, serpins, and IL-1 .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Hu01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Hu02 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Hu03 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Hu01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Hu22 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
PAA101Hu02 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
PAA101Hu03 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Hu21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
LAA101Hu72 Biotin-Linked Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC.
Assay Kits SEA101Hu ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Hu CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Mu01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Mu02 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Mu01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
PAA101Mu02 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Mu ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Mu CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Ra01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Ra02 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Ra01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
LAA101Ra71 Biotin-Linked Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC.
LAA101Ra81 FITC-Linked Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IF.
MAA101Ra21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
PAA101Ra02 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Ra ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Ra CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Rb01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Rb51 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Rb21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Rb ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Rb CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Ca01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Ca01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Ca21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Ca ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Ca CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Po01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Po01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Po21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Po ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Po CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Bo01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Bo01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Bo21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Bo ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Bo CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA101Eq01 Recombinant Matrix Metalloproteinase 3 (MMP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA101Eq01 Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
MAA101Eq21 Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) WB; IHC; ICC; IP.
Assay Kits SEA101Eq ELISA Kit for Matrix Metalloproteinase 3 (MMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Eq CLIA Kit for Matrix Metalloproteinase 3 (MMP3) Chemiluminescent immunoassay for Antigen Detection.
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