Interleukin 1 Alpha (IL1a)

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IL1-A; IL-1α; IL1F1; Preinterleukin 1 Alpha; Hematopoietin-1; Pro-Interleukin-1-Alpha; Interleukin-1 Family Member 1

Interleukin 1 Alpha (IL1a)

IL-1α is a member of interleukin 1 family. IL-1α and IL-1β recognize the same IL-1 receptor and share a number of similar biological functions. IL-1α is predominantly a cell-associated molecule whereas IL-1β is a secreted molecule.

IL-1α is synthesized primarily as a 31 kDa precursor that lacks a signal peptide. Cleavage of the precursor is via the cysteine protease calpain, resulting in a 17.5 kDa mature IL-1 molecule. Being active in the processed form, the IL-1 precursor is also biologically active via specific cell binding. A portion of the precursor is transported to the cell surface and associated with the cell membrane. Precursor IL-1α can be released and cleaved by extracellular proteases when the cells die, and can also be cleaved by activation of the calcium-dependent, membrane-associated calpains.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Hu01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPA071Hu02 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
APA071Hu01 Active Interleukin 1 Alpha (IL1a) Cell culture; Activity Assays.
Antibodies PAA071Hu01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
MAA071Hu22 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Hu71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
LAA071Hu81 FITC-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IF.
MAA071Hu21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
PAA071Hu02 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Hu72 Biotin-Linked Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
Assay Kits SEA071Hu ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Mu01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPA071Mu02 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Mu01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
PAA071Mu02 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
Assay Kits SEA071Mu ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA071Mu High Sensitive ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Ra01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPA071Ra02 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Ra01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
PAA071Ra02 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
MAA071Ra22 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Ra71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
Assay Kits SEA071Ra ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA071Ra High Sensitive ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Gu01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Gu01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
MAA071Gu21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
Assay Kits SEA071Gu ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Rb01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPA071Rb02 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Rb52 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
PAA071Rb51 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Rb71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
Assay Kits SEA071Rb ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Ca01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPA071Ca02 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Ca01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Ca71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
MAA071Ca21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
PAA071Ca02 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
Assay Kits SEA071Ca ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Po01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Po01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Po71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
MAA071Po21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
Assay Kits SEA071Po ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Bo01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Bo01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
MAA071Bo21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
Assay Kits SEA071Bo ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Cp01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Cp01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Cp71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
MAA071Cp22 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Cp72 Biotin-Linked Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
Assay Kits HEA071Cp High Sensitive ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA071Cp ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Ov01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Ov01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
MAA071Ov21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
Assay Kits SEA071Ov ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA071Eq01 Recombinant Interleukin 1 Alpha (IL1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA071Eq01 Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Eq71 Biotin-Linked Polyclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
MAA071Eq21 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
MAA071Eq24 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Eq74 Biotin-Linked Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
MAA071Eq26 Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC; IP.
LAA071Eq76 Biotin-Linked Monoclonal Antibody to Interleukin 1 Alpha (IL1a) WB; IHC; ICC.
Assay Kits SEA071Eq ELISA Kit for Interleukin 1 Alpha (IL1a) Enzyme-linked immunosorbent assay for Antigen Detection.
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  12. "The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece."Proc. Natl. Acad. Sci. U.S.A. 90:7245-7249(1993) [PubMed] [Europe PMC] [Abstract]
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