Family With Sequence Similarity 227, Member B (FAM227B)
[Edit]C15orf33; Chromosome 15 Open Reading Frame 33
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Chromosome 15 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 15 spans about 106 million base pairs (the building material of DNA) and represents between 3% and 3.5% of the total DNA in cells.
A type of blood cancer known as acute promyelocytic leukemia is caused by a rearrangement (translocation) of genetic material between chromosomes 15 and 17. This translocation, written as t(15;17), fuses part of the PML gene from chromosome 15 with part of the RARA gene from chromosome 17. This mutation is acquired during a person's lifetime and is present only in certain cells. This type of genetic change, called a somatic mutation, is not inherited.
A type of blood cancer known as acute promyelocytic leukemia is caused by a rearrangement (translocation) of genetic material between chromosomes 15 and 17. This translocation, written as t(15;17), fuses part of the PML gene from chromosome 15 with part of the RARA gene from chromosome 17. This mutation is acquired during a person's lifetime and is present only in certain cells. This type of genetic change, called a somatic mutation, is not inherited.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Family With Sequence Similarity 227, Member B (FAM227B) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Family With Sequence Similarity 227, Member B (FAM227B) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Family With Sequence Similarity 227, Member B (FAM227B) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Family With Sequence Similarity 227, Member B (FAM227B) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Family With Sequence Similarity 227, Member B (FAM227B) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Family With Sequence Similarity 227, Member B (FAM227B) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Family With Sequence Similarity 227, Member B (FAM227B) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Family With Sequence Similarity 227, Member B (FAM227B) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Family With Sequence Similarity 227, Member B (FAM227B) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Family With Sequence Similarity 227, Member B (FAM227B) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]