DEAD Box Polypeptide 60 (DDX60)

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Asp-Glu-Ala-Asp Box Polypeptide 60; Probable ATP-dependent RNA helicase DDX60

DEAD Box Polypeptide 60 (DDX60)
DDX60 Belongs to the helicase family.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain. The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. DEAD box proteins are involved in an assortment of metabolic processes that involve RNA. DEAD box proteins were first brought to attention in the late 1980s in a study that looked at a group of NTPases that were similar in sequence to the eIF4A RNA helicase sequence. The results of this study showed that these proteins (p68,SrmB, MSS116, vasa, PL10, mammalian eIF4A, yeast eIF4A) involved in RNA metabolism had several common elements. There were nine common sequences found to be conserved amongst the studied species, which is an important criterion of the DEAD box family.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DEAD Box Polypeptide 60 (DDX60) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DEAD Box Polypeptide 60 (DDX60) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DEAD Box Polypeptide 60 (DDX60) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DEAD Box Polypeptide 60 (DDX60) CLIA Kit Customized Service Offer
n/a ELISA Kit for DEAD Box Polypeptide 60 (DDX60) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DEAD Box Polypeptide 60 (DDX60) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DEAD Box Polypeptide 60 (DDX60) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DEAD Box Polypeptide 60 (DDX60) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DEAD Box Polypeptide 60 (DDX60) CLIA Kit Customized Service Offer
n/a ELISA Kit for DEAD Box Polypeptide 60 (DDX60) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DEAD Box Polypeptide 60 (DDX60) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DEAD Box Polypeptide 60 (DDX60) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DEAD Box Polypeptide 60 (DDX60) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DEAD Box Polypeptide 60 (DDX60) CLIA Kit Customized Service Offer
n/a ELISA Kit for DEAD Box Polypeptide 60 (DDX60) ELISA Kit Customized Service Offer
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling."Mol. Cell. Biol. 31:3802-3819(2011) [PubMed] [Europe PMC] [Abstract]
  5. "A diverse range of gene products are effectors of the type I interferon antiviral response."Nature 472:481-485(2011) [PubMed] [Europe PMC] [Abstract]