IGF Like Family Receptor 1 (IGFLR1)
[Edit]TMEM149; U2AF1L4; Transmembrane Protein 149; U2 RNU2 Small Nuclear RNA Auxiliary Factor 1-Like 4
-88133.gif)
Psoriasis is a human skin condition characterized by epidermal hyperproliferation and infiltration of multiple leukocyte populations. IGFL1, was uniquely and significantly induced in psoriatic skin samples. In vitro IGFL1 expression was up-regulated in cultured primary keratinocytes stimulated with tumor necrosis factor α but not by other psoriasis-associated cytokines.
TMEM149is an uncharacterized gene with structural similarity to the tumor necrosis factor receptor family. is expressed primarily on the surface of mouse T cells. The connection between mIGFL and IGFLR1 receptor suggests mIGFL may influence T cell biology within inflammatory skin conditions.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant IGF Like Family Receptor 1 (IGFLR1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to IGF Like Family Receptor 1 (IGFLR1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to IGF Like Family Receptor 1 (IGFLR1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for IGF Like Family Receptor 1 (IGFLR1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for IGF Like Family Receptor 1 (IGFLR1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant IGF Like Family Receptor 1 (IGFLR1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to IGF Like Family Receptor 1 (IGFLR1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to IGF Like Family Receptor 1 (IGFLR1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for IGF Like Family Receptor 1 (IGFLR1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for IGF Like Family Receptor 1 (IGFLR1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant IGF Like Family Receptor 1 (IGFLR1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to IGF Like Family Receptor 1 (IGFLR1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to IGF Like Family Receptor 1 (IGFLR1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for IGF Like Family Receptor 1 (IGFLR1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for IGF Like Family Receptor 1 (IGFLR1) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Murine IGFL and human IGFL1 are induced in inflammatory skin conditions and bind to a novel TNF receptor family member, IGFLR1."J. Biol. Chem. 286:18969-18981(2011) [PubMed] [Europe PMC] [Abstract]