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Growth Arrest Specific 2 Like Protein 3 (GAS2L3)

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Growth Arrest Specific 2 Like Protein 3 (GAS2L3)
CCC T724
HGNC 27475
MGI 1918780
PubMed 23469016
RGD 1594151
UniProt Q86XJ1
Gas2, a 313 amino acid protein, is ubiquitously expressed with highest levels found in liver, lung and kidney, and is thought to play a role in apoptosis by acting as a cell death substrate for caspases. One of several components of the microfilament system, Gas2 is cleaved by either caspase-3 or caspase-7 at Asp 278 during apoptosis, an event which induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cell.
Gas2L3 (growth arrest-specific 2 like 3) is a 694 amino acid protein that contains one calponin-homology (CH) domain and may function in a similar manner to Gas2. The gene encoding Gas2L3 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Growth Arrest Specific 2 Like Protein 3 (GAS2L3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Growth Arrest Specific 2 Like Protein 3 (GAS2L3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Growth Arrest Specific 2 Like Protein 3 (GAS2L3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Growth Arrest Specific 2 Like Protein 3 (GAS2L3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Growth Arrest Specific 2 Like Protein 3 (GAS2L3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Growth Arrest Specific 2 Like Protein 3 (GAS2L3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Growth Arrest Specific 2 Like Protein 3 (GAS2L3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of G2L3 (GAS2-like 3), a new microtubule- and actin-binding protein related to spectraplakins."J. Biol. Chem. 286:24987-24995(2011) [PubMed] [Europe PMC] [Abstract]