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Leucine Rich Repeat Containing Protein 4B (LRRC4B)

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HSM; LRIG4; NGL-3; Netrin-G3 ligand; Leucine-Rich Repeats And Immunoglobulin-Like Domains 4

Leucine Rich Repeat Containing Protein 4B (LRRC4B)
CCC S728
HGNC 25042
MGI 3027390
PubMed 19285470
RGD 1307121
UniProt Q9NT99
LRRC4B is a synaptic adhesion protein. It regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and LAR regulates excitatory synapse formation in a bidirectional manner.
LRRC4 are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. Mature LRRC4 family members are type I transmembrane proteins with an extracellular region that contains nine LRRs, a C2-type Ig-like domain, and a Thr-rich segment. LRRC4 family members share ~55% aa identity, but each recognizes different ligands. LRRC4 and LRRC4C recognize Netrin-G2 and Netrin-G3, respectively, while LRRC4B recognizes the receptor tyrosine phosphatases LAR/PTPRF, PTPR delta and PTPR sigma.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS728Hu01 Recombinant Leucine Rich Repeat Containing Protein 4B (LRRC4B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS728Hu21 Monoclonal Antibody to Leucine Rich Repeat Containing Protein 4B (LRRC4B) WB; IHC; ICC; IP.
PAS728Hu01 Polyclonal Antibody to Leucine Rich Repeat Containing Protein 4B (LRRC4B) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Leucine Rich Repeat Containing Protein 4B (LRRC4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeat Containing Protein 4B (LRRC4B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeat Containing Protein 4B (LRRC4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeat Containing Protein 4B (LRRC4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeat Containing Protein 4B (LRRC4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeat Containing Protein 4B (LRRC4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeat Containing Protein 4B (LRRC4B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeat Containing Protein 4B (LRRC4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeat Containing Protein 4B (LRRC4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeat Containing Protein 4B (LRRC4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeat Containing Protein 4B (LRRC4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeat Containing Protein 4B (LRRC4B) ELISA Kit Customized Service Offer
  1. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]