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The fibrinogen binding inhibitor peptide (FBIP), representing the dodecapeptide sequence in human fibrinogen g-chain, was also added to thrombocyte preparations prior to the addition of U-46619 in the presence of trout fibrinogen. The apparent lack of inhibition by the dodecapeptide sequence (FBIP) is, however, indicative of a lack of sequence homology between trout and human fibrinogen within the a chain. The FBIP peptide at a concentration of 340uM and the GRGDSPK peptide at a concentration of 140 uM had no effect on 3T3-19 adhesion to C. albicans hyphae. Fibrinogen (factor I) is a a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. Processes in the coagulation cascade activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | CPS102Hu21 | OVA Conjugated Fibrinogen Binding Inhibitor Peptide (FBIP) | Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Fibrinogen Binding Inhibitor Peptide (FBIP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Fibrinogen Binding Inhibitor Peptide (FBIP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Fibrinogen Binding Inhibitor Peptide (FBIP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibrinogen Binding Inhibitor Peptide (FBIP) | ELISA Kit Customized Service Offer |