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Thioredoxin Domain Containing Protein 11 (TXNDC11)

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EFP1; EF-Hand Binding Protein 1

Thioredoxin Domain Containing Protein 11 (TXNDC11)
CCC R759
HGNC 28030
MGI 1923620
PubMed 15561711
RGD 1307538
UniProt Q6PKC3
TXNDC11, Belongs to the protein disulfide isomerase family.Contains 2 thioredoxin domains.Widely expressed at low level. Expressed at higher level in thyroid and prostate.May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H2O2 generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H2O2 generation.
Thioredoxinsare small disulphide-containing redox proteins that have been found in all the kingdoms of living organisms. Thioredoxin serves as a general protein disulphide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulphide, accompanied by the transfer of 2 electrons and 2 protons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thioredoxin Domain Containing Protein 11 (TXNDC11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thioredoxin Domain Containing Protein 11 (TXNDC11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thioredoxin Domain Containing Protein 11 (TXNDC11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thioredoxin Domain Containing Protein 11 (TXNDC11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thioredoxin Domain Containing Protein 11 (TXNDC11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thioredoxin Domain Containing Protein 11 (TXNDC11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thioredoxin Domain Containing Protein 11 (TXNDC11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thioredoxin Domain Containing Protein 11 (TXNDC11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thioredoxin Domain Containing Protein 11 (TXNDC11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thioredoxin Domain Containing Protein 11 (TXNDC11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thioredoxin Domain Containing Protein 11 (TXNDC11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thioredoxin Domain Containing Protein 11 (TXNDC11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thioredoxin Domain Containing Protein 11 (TXNDC11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thioredoxin Domain Containing Protein 11 (TXNDC11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thioredoxin Domain Containing Protein 11 (TXNDC11) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of a novel partner of duox: EFP1, a thioredoxin-related protein."J. Biol. Chem. 280:3096-3103(2005) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction."Mol. Cell. Proteomics 6:1952-1967(2007) [PubMed] [Europe PMC] [Abstract]