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Neugrin (NGRN)

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Neurite Outgrowth Associated; Mesenchymal stem cell protein DSC92; Spinal cord-derived protein FI58G

Neugrin (NGRN)
CCC Q644
HGNC 18077
MGI 1933212
RGD 1583734
UniProt Q9NPE2
The neugrin mRNA encodes 219 amino acids and its deduced amino acid sequence contains an NLS-like domain. No previously known motif is found in it. m-neugrin mRNA encodes 233 amino acids. Neugrin and m-Neugrin are 70% homologous in amino acid sequence. Northern analysis revealed that neugrin was strongly expressed in the heart, brain, and skeletal muscle, and m-neugrin in the liver, kidney, and brain. A transfection study indicated that these proteins are localized in the nucleus. Although the expression of neugrin was found to be ubiquitous in the nervous system, in situ hybridization showed that both neugrin and m-neugrin were expressed mainly in the neurons rather than the glial cells. Their expression was highly upregulated with the neurite outgrowth associated with neuronal differentiation in neuroblastoma cell lines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ644Hu01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAQ644Hu01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
MAQ644Hu21 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
Assay Kits SEQ644Hu ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neugrin (NGRN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neugrin (NGRN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neugrin (NGRN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neugrin (NGRN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neugrin (NGRN) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neugrin (NGRN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neugrin (NGRN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neugrin (NGRN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neugrin (NGRN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neugrin (NGRN) ELISA Kit Customized Service Offer
  1. "Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells."Biochem. Biophys. Res. Commun. 279:526-533(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]