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Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1)

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GBP; TMEM132A; Glucose Regulated Protein,78kDa Binding Protein 1; Transmembrane Protein 132A; HSPA5-binding protein 1

Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1)
CCC M649
HGNC 31092
MGI 2147810
RGD 727936
UniProt Q24JP5
GBP was predominantly expressed in neuronal cells among various brain tissues. GBP mRNA was already detected in the E12 brain and then gradually increased to reach a peak within P0-2 weeks after birth.
GBP expression in the brain decreased age-dependently to approximately 30% of the postnatal level at 12 months. GBP encoded 1021 amino acids and was predicted to have two transmembrane regions and glutamic acid- and proline-rich regions. Observation of COS7 cells expressing green fluorescent protein- or Myc-tagged GBP showed that GBP was localized in the endoplasmic reticulum-Golgi domain where BODIPY 558/568 (4,4-difluro-5-(2-thienyl)-4-bora-3alpha,4alpha-diaza-S-indacene)-labeled brefeldin A accumulated. GBP would have a relevant functional role in embryonic and postnatal development of the brain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heat Shock 70kDa Protein 5 Binding Protein 1 (HSPA5BP1) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]