Actin Like Protein 6A (ACTL6A)
[Edit]Actl6; BAF53A; Arp4; Baf53a; INO80K; BAF Complex 53 kDa Subunit; 53 kDa BRG1-associated factor A; Actin-Related Protein 4; INO80 Complex Subunit K
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ACTL6A encodes a family member of actin-related proteins (ARPs), The 429-amino acid BAF53 protein shares extensive amino acid homology with actin and the yeast actin-related proteins Act2 and Act3. In addition, sequences encoding BAF53 homologs were identified in yeast and C. elegans. Two of 3 amino acids (asp11, gln137, and asp154 in actin) involved in tight calcium binding are conserved (asp17 and asp171 in BAF53).
In contrast with the overall homology to actin, the ATP-binding pocket in actin is poorly conserved in BAF53, suggesting that BAF53 may not have ATP-binding activity. A comparison of the sequences of actin family members revealed that BAF53 is most related to Arp3, which is involved in Listeria motility.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Actin Like Protein 6A (ACTL6A) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Actin Like Protein 6A (ACTL6A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Actin Like Protein 6A (ACTL6A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEK268Hu | ELISA Kit for Actin Like Protein 6A (ACTL6A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Actin Like Protein 6A (ACTL6A) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Actin Like Protein 6A (ACTL6A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Actin Like Protein 6A (ACTL6A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Actin Like Protein 6A (ACTL6A) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Actin Like Protein 6A (ACTL6A) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Actin Like Protein 6A (ACTL6A) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Actin Like Protein 6A (ACTL6A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Actin Like Protein 6A (ACTL6A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Actin Like Protein 6A (ACTL6A) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Actin Like Protein 6A (ACTL6A) | ELISA Kit Customized Service Offer |
- "Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling."Cell 95:625-636(1998) [PubMed] [Europe PMC] [Abstract]
- "Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues."Biosci. Biotechnol. Biochem. 63:917-923(1999) [PubMed] [Europe PMC] [Abstract]
- "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]