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Zinc Finger Protein, X-Linked (ZFX)

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Zinc Finger Protein, X-Linked (ZFX)
CCC K041
HGNC 12869
MGI 99211
PubMed 2041734
RGD 1562664
UniProt P17010
Wiki ZFX
ZFX on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein, X-Linked (ZFX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein, X-Linked (ZFX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein, X-Linked (ZFX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein, X-Linked (ZFX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein, X-Linked (ZFX) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein, X-Linked (ZFX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein, X-Linked (ZFX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein, X-Linked (ZFX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein, X-Linked (ZFX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein, X-Linked (ZFX) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein, X-Linked (ZFX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein, X-Linked (ZFX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein, X-Linked (ZFX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein, X-Linked (ZFX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein, X-Linked (ZFX) ELISA Kit Customized Service Offer
  1. "Putative transcription activator with alternative isoforms encoded by human ZFX gene."Nature 342:708-711(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Comparison of human ZFY and ZFX transcripts."Proc. Natl. Acad. Sci. U.S.A. 87:1681-1685(1990) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation."Cell 57:1247-1258(1989) [PubMed] [Europe PMC] [Abstract]
  6. "Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY."Nucleic Acids Res. 19:2579-2586(1991) [PubMed] [Europe PMC] [Abstract]