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Epsin 2 (EPN2)

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EHB21; Eps15 Binding Protein 2; EPS-15-interacting protein 2

Epsin 2 (EPN2)
CCC J142
HGNC 18639
MGI 1333766
PubMed 9303539
RGD 619773
UniProt O95208
Wiki EPN2
EPN2 encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in two transcript variants encoding different isoforms.The deduced 431-amino acid EPN2 protein has a domain structure similar to that of EPN1, consisting of an epsin N-terminal homology (ENTH) region, a central region containing DPW repeats and an LLDL clathrin-binding sequence, and a C-terminal EPS15 homology (EH) domain-binding region containing 3 NPF repeats. However, unlike EPN1, EPN2 has no CDC2 phosphorylation site.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epsin 2 (EPN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epsin 2 (EPN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epsin 2 (EPN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epsin 2 (EPN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epsin 2 (EPN2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epsin 2 (EPN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epsin 2 (EPN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epsin 2 (EPN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epsin 2 (EPN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epsin 2 (EPN2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epsin 2 (EPN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epsin 2 (EPN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epsin 2 (EPN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epsin 2 (EPN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epsin 2 (EPN2) ELISA Kit Customized Service Offer
  1. "The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module."J. Biol. Chem. 274:33959-33965(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]