Eca-109

Eca-109 cells are derived from a moderately differentiated human esophageal squamous cell carcinoma. These cells were first established and characterized in a study by R. Jin et al. in 1980. Eca-109 cells are widely used in research related to esophageal cancer, cancer biology, oncology, and drug screening due to their tumorigenic properties and relevance to the study of esophageal cancer.

Eca-109 cells exhibit certain characteristics typical of cancer cells, such as rapid proliferation, anchorage-independent growth, and the ability to form tumors in xenograft models. They are commonly used as a model system for studying the biology of esophageal cancer, including its molecular mechanisms, signaling pathways, drug response, and potential therapeutic strategies.

Researchers often use Eca-109 cells in various in vitro experiments, such as cell proliferation assays, migration and invasion assays, drug screening assays, and molecular biology studies. Additionally, Eca-109 cells are employed in xenograft models to investigate tumor growth, metastasis, and response to experimental therapies in vivo.