SW-13

SW-13 is a cell line exhibiting epithelial morphology that was isolated in 1971 from the adrenal gland and cortex of a White, 55-year-old, female patient with carcinoma. Adrenocortical carcinoma is a rare and aggressive cancer that originates in the adrenal cortex, which is a part of the endocrine system responsible for producing hormones such as cortisol and aldosterone.

SW-13 cells have been employed in various studies exploring the genetic and epigenetic changes associated with adrenocortical carcinoma, as well as in drug screening assays to identify potential treatments for this aggressive cancer. The SW-13 cell line is commercially available and continues to be a critical tool in advancing our understanding of adrenocortical carcinoma and developing new treatment strategies for patients with this disease.