Lymphatic Mononuclear Cells (LMC)

A lymph node is an oval or kidney-shaped organ of the lymphatic system, distributed widely throughout the body including the armpit and stomach and linked by lymphatic vessels. Lymph nodes are major sites of B, T, and other immune cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles and cancer cells.

Lymphatic mononuclear cells (LMC) are located in the lymph nodes and perform vital functions for the innate and adaptive immune system. Lymphatic mononuclear cells are a mixed population of single nucleus cells which include T-cells (helper T-cells, cytotoxic T-cells, gamma delta T-cells), B-cells, and natural killer (NK) cells. Clutured mouse LMC can be used to study the innate and adaptive immune system.