Lymphatic Endothelial Cells (LEC)

Lymphatic system is an important part of the immune system. It helps to maintain tissue homeostasis, including interstitial protein transport, tissue fluid balance, and cellular immunity. Lymphatic vessels are located under the skin and are often associated with superficial vein, collecting the lymph nodes of the skin and subcutaneous tissue. Deep lymphatic vessels and deep blood vessels, the collection of muscle and visceral lymph. There is a wide range of communicating branches between shallow and deep lymphatic vessels. Lymphatic Endothelial Cells (LEC) are the main structure of the lymphatic vessel wall, which participates in the process of maintaining the balance of body fluid, regulating the recycling of lymphocytes and the immune response of the body. Recent studies have indicated that LEC plays an important role in the pathological process of wound healing, lymphatic edema and inflammation, and is closely related to the metastasis of tumor.