Glycoprotein A33 (GPA33)

[Edit]

Cell surface A33 antigen

Glycoprotein A33 (GPA33)
GPA33 is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycoprotein A33 (GPA33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycoprotein A33 (GPA33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycoprotein A33 (GPA33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycoprotein A33 (GPA33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycoprotein A33 (GPA33) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycoprotein A33 (GPA33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycoprotein A33 (GPA33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycoprotein A33 (GPA33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycoprotein A33 (GPA33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycoprotein A33 (GPA33) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH984Ra01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAH984Ra21 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAH984Ra01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
Assay Kits SEH984Ra ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily."Proc. Natl. Acad. Sci. U.S.A. 94:469-474(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium."Biochem. Biophys. Res. Commun. 236:682-686(1997) [PubMed] [Europe PMC] [Abstract]