≡

Oncomodulin (OCM)

[Edit]

OCM1; OCMN; OM; Parvalbumin beta

Oncomodulin (OCM)
CCC H506
HGNC 8105
PubMed 22078758
UniProt P0CE72
Wiki Oncomodulin
Oncomodulin and parvalbumin are structurally closely related, high-affinity calcium ion-binding proteins. Both belong to the superfamily of calmodulin proteins, also termed EF-hand proteins. Intron/exon organizations of the parvalbumin and oncomodulin genes are identical and the coding sequences are moderately similar, suggesting a common ancestor. Oncomodulin is a an oncodevelopmental protein found in early embryonic cells, in the placenta, and in tumors; parvalbumin is synthesized at highest levels in muscle fibers of the IIB type and in most GABAergic cells of the brain.
Analysis of human-mouse hybrids retaining portions of human chromosome 7 allowed specific assignment of the gene locus to 7p13-p11.the oncomodulin gene map to mouse chromosome 5.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH506Hu01 Recombinant Oncomodulin (OCM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH506Hu01 Polyclonal Antibody to Oncomodulin (OCM) WB
Assay Kits n/a CLIA Kit for Oncomodulin (OCM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oncomodulin (OCM) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH506Mu01 Recombinant Oncomodulin (OCM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH506Mu01 Polyclonal Antibody to Oncomodulin (OCM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Oncomodulin (OCM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oncomodulin (OCM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH506Ra01 Recombinant Oncomodulin (OCM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH506Ra01 Polyclonal Antibody to Oncomodulin (OCM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Oncomodulin (OCM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oncomodulin (OCM) ELISA Kit Customized Service Offer
  1. "Human alpha and beta parvalbumins. Structure and tissue-specific expression."Eur. J. Biochem. 215:719-727(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Solution structure of human beta-parvalbumin and structural comparison with its paralog alpha-parvalbumin and with their rat orthologs."Biochemistry 43:16076-16085(2004) [PubMed] [Europe PMC] [Abstract]