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Dipeptidyl Peptidase 9 (DPP9)

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DPRP2; DPLP9; Dipeptidylpeptidase 9; Dipeptidyl peptidase IV-related protein 2; Dipeptidyl peptidase-like protein 9; Dipeptidyl peptidase IX

Dipeptidyl Peptidase 9 (DPP9)
CCC G444
HGNC 18648
MGI 2443967
PubMed 19667070
RGD 1588575
UniProt Q86TI2
Wiki DPP9
Dipeptidyl peptidase 9 is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins.
Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG444Hu01 Recombinant Dipeptidyl Peptidase 9 (DPP9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Dipeptidyl Peptidase 9 (DPP9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dipeptidyl Peptidase 9 (DPP9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dipeptidyl Peptidase 9 (DPP9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dipeptidyl Peptidase 9 (DPP9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG444Mu01 Recombinant Dipeptidyl Peptidase 9 (DPP9) Positive Control; Immunogen; SDS-PAGE; WB.
RPG444Mu02 Recombinant Dipeptidyl Peptidase 9 (DPP9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG444Mu01 Polyclonal Antibody to Dipeptidyl Peptidase 9 (DPP9) WB; IHC; ICC; IP.
PAG444Mu02 Polyclonal Antibody to Dipeptidyl Peptidase 9 (DPP9) WB; IHC; ICC; IP.
Assay Kits SEG444Mu ELISA Kit for Dipeptidyl Peptidase 9 (DPP9) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dipeptidyl Peptidase 9 (DPP9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dipeptidyl Peptidase 9 (DPP9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dipeptidyl Peptidase 9 (DPP9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dipeptidyl Peptidase 9 (DPP9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dipeptidyl Peptidase 9 (DPP9) ELISA Kit Customized Service Offer
  1. "Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV."Gene 299:185-193(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases."Biochem. J. 373:179-189(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity."Biochim. Biophys. Acta 1679:18-28(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV."Biochem. J. 396:391-399(2006) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus."Cell. Mol. Life Sci. 71:3611-3626(2014) [PubMed] [Europe PMC] [Abstract]