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Sex Determining Region Y Box Protein 15 (SOX15)

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SOX12; SOX20; SOX26; SOX27

Sex Determining Region Y Box Protein 15 (SOX15)
CCC G335
HGNC 11196
MGI 98363
PubMed 16759287
RGD 1312022
UniProt O60248
Wiki SOX15
SOX15 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Sox15-null mice were viable and fertile and showed normal skeletal muscle development. In particular, satellite cells were normal, excluding a role for Sox15 in the development of satellite cells; however, skeletal muscle regeneration was impaired in the Sox15-null mice after crush injury, and cultured Sox15-null myoblasts displayed a marked delay in differentiation potential compared to wildtype cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sex Determining Region Y Box Protein 15 (SOX15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sex Determining Region Y Box Protein 15 (SOX15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sex Determining Region Y Box Protein 15 (SOX15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sex Determining Region Y Box Protein 15 (SOX15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sex Determining Region Y Box Protein 15 (SOX15) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sex Determining Region Y Box Protein 15 (SOX15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sex Determining Region Y Box Protein 15 (SOX15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sex Determining Region Y Box Protein 15 (SOX15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sex Determining Region Y Box Protein 15 (SOX15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sex Determining Region Y Box Protein 15 (SOX15) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sex Determining Region Y Box Protein 15 (SOX15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sex Determining Region Y Box Protein 15 (SOX15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sex Determining Region Y Box Protein 15 (SOX15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sex Determining Region Y Box Protein 15 (SOX15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sex Determining Region Y Box Protein 15 (SOX15) ELISA Kit Customized Service Offer
  1. "Isolation and expression of a human SRY-related cDNA hSOX20."Biochim. Biophys. Acta 1396:132-137(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "SOX20, a new member of the SOX gene family, is located on chromosome 17p13."Cytogenet. Cell Genet. 72:246-249(1996) [PubMed] [Europe PMC] [Abstract]
  6. "Partial cloning of SOX-11 and SOX-12, two new human SOX genes."Nucleic Acids Res. 21:2943-2943(1993) [PubMed] [Europe PMC] [Abstract]
  7. "cDNA characterization and high resolution mapping of the human SOX20 gene."Mamm. Genome 9:1059-1061(1998) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]