Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)
[Edit]BDGI; OKL38; Bone Marrow Stromal Cell-Derived Growth Inhibitor; Pregnancy Induced Growth Inhibitor; Ovary, kidney and liver protein 38
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The deduced 317-amino acid protein has a calculated molecular mass of about 34.5 kD. OKL38 does not have a transmembrane domain or signal peptide. Minor transcripts of 3.6 and 4.0 kb were also observed.
In situ hybridization detected Okl38 in undifferentiated mammary epithelial cells of nonpregnant rats, and expression was upregulated in secretory epithelial of 18-day pregnant rats. Northern blot analysis detected reduced OKL38 expression in human breast cancer cell lines compared with normal mammary tissue. Expression was also reduced in chemically-induced rat mammary tumors. Overexpression of OKL38 in a human breast cancer cell line reduced the ability of these cells to form tumors in nude mice.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG202Hu01 | Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG202Hu21 | Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | WB; IHC; ICC; IP. |
| PAG202Hu01 | Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEG202Hu | ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) | ELISA Kit Customized Service Offer |
- "Genomic structure of human OKL38 gene and its differential expression in kidney carcinogenesis."J. Biol. Chem. 279:743-754(2004) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Cloning and characterization of a novel pregnancy-induced growth inhibitor in mammary gland."Endocrinology 142:3607-3615(2001) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]