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Brain Specific Angiogenesis Inhibitor 3 (BAI3)

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Brain Specific Angiogenesis Inhibitor 3 (BAI3)
CCC F233
HGNC 945
MGI 2441837
PubMed 21262840
RGD 1309703
UniProt O60242
Brain-specific angiogenesis inhibitors are G-protein coupled receptors belonging to the class B secretin subfamily. Might be involved in angiogenesis inhibition and suppression of glioblastoma.Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines. BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis. C1ql proteins are secreted signaling molecules that bind to BAI3 and act, at least in part, to regulate synapse formation and/or maintenance.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF233Hu01 Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF233Hu01 Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) WB; IHC; ICC; IP.
MAF233Hu21 Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) WB; IHC; ICC; IP.
MAF233Hu23 Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) WB; IHC; ICC; IP.
MAF233Hu22 Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) WB; IHC; ICC; IP.
MAF233Hu24 Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) WB; IHC; ICC; IP.
Assay Kits SEF233Hu ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)."Cytogenet. Cell Genet. 79:103-108(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins."Proc. Natl. Acad. Sci. U.S.A. 108:2534-2539(2011) [PubMed] [Europe PMC] [Abstract]
  9. "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis."EMBO J. 31:1364-1378(2012) [PubMed] [Europe PMC] [Abstract]