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Adenylate Kinase 3 (AK3)

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AK3L1; AK6; AKL3L; Adenylate Kinase 3 Alpha-Like 1; GTP:AMP Phosphotransferase AK3, Mitochondrial

Adenylate Kinase 3 (AK3)
CCC F205
HGNC 17376
MGI 1860835
PubMed 1639383
RGD 619885
UniProt Q9UIJ7
The deduced 227-amino acid protein has a calculated molecular mass of 25.6 kD. AK3 shares 57.4% amino acid identity with AK4 (AK3L1). It shares 75%, 90%, and 91% amino acid identity with bovine, rat, and mouse Ak3, respectively. Northern blot analysis detected a 3.2-kb transcript in all tissues examined. Expression was highest in heart, liver, and skeletal muscle, moderate in kidney and pancreas, and weak in brain, placenta, and lung. Transcripts of 5, 1.8, and 1.35 kb were detected in heart, liver, and pancreas. Western blot analysis detected AK3 at an apparent molecular mass of 28 kD in all tissues examined. Subcellular fractionation of mouse liver and kidney detected Ak3 in the mitochondrial fraction.Human embryonic kidney cells had endogenous phosphotransferase activity, which increased following transfection of AK3 cDNA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF205Hu01 Recombinant Adenylate Kinase 3 (AK3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF205Hu01 Polyclonal Antibody to Adenylate Kinase 3 (AK3) WB
MAF205Hu21 Monoclonal Antibody to Adenylate Kinase 3 (AK3) WB; IHC; ICC; IP.
Assay Kits SEF205Hu ELISA Kit for Adenylate Kinase 3 (AK3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adenylate Kinase 3 (AK3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adenylate Kinase 3 (AK3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adenylate Kinase 3 (AK3) Polyclonal Antibody Customized Service Offer
Assay Kits SEF205Mu ELISA Kit for Adenylate Kinase 3 (AK3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adenylate Kinase 3 (AK3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adenylate Kinase 3 (AK3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adenylate Kinase 3 (AK3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Adenylate Kinase 3 (AK3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Adenylate Kinase 3 (AK3) ELISA Kit Customized Service Offer
  1. "Structure and expression of human mitochondrial adenylate kinase targeted to the mitochondrial matrix."Biochem. J. 358:225-232(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  7. "Structure of human adenylate kinase 3-like 1."Submitted (MAY-2005) to the PDB data bank