Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3)

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GLUR-K3; GLUR3; GLURC; gluR-C; AMPA-selective glutamate receptor 3

Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3)
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists.
Glutamate receptor 3 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternative splicing at this locus results in several different isoforms which may vary in their signal transduction properties.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE803Hu01 Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE803Hu01 Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) WB; ICC; IHC-P; IHC-F; ELISA.
MAE803Hu21 Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) WB; IHC; ICC; IP.
Assay Kits SEE803Hu ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE803Mu01 Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Positive Control; Immunogen; SDS-PAGE; WB.
RPE803Mu02 Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE803Mu01 Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) WB; IHC; ICC; IP.
PAE803Mu02 Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) WB; IHC; ICC; IP.
Assay Kits SEE803Mu ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) ELISA Kit Customized Service Offer
  1. "Human glutamate receptor hGluR3 flip and flop isoforms: cloning and sequencing of the cDNAs and primary structure of the proteins."Biochim. Biophys. Acta 1219:563-566(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation."Genomics 62:356-368(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq."Am. J. Med. Genet. 90:69-71(2000) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins."Neuron 68:1082-1096(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans." Proc. Natl. Acad. Sci. U.S.A. 104:18163-18168(2007) [PubMed] [Europe PMC] [Abstract]