Annexin A11 (ANXA11)

[Edit]

ANX-A11; ANX11; CAP50; 56 kDa autoantigen; Calcyclin-associated annexin 50

Annexin A11 (ANXA11)
Annexin A11 isa 56-kD antigen recognized by sera from patients with various autoimmune diseases. Exon 1 is untranslated, and intron 1 spans about 20 kb. The human ANXA11 gene has the same general structure as the mouse gene; however, EST database analysis indicated that human ANXA11 transcripts also use variably spliced exons 1b and 1c, which can lengthen the 5-prime UTR. The intronic sequences of the mouse and human ANXA11 genes contain several types of repetitive elements, including retroviral long terminal repeats. The mouse promoter region contains a remnant LINE-1 insertion not found in the human gene. The 5-prime flanking region of the ANXA11 gene contains a CpG island and MYOD, SP1, and glucocorticoid response elements, but no proximal TATA or CAAT boxes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE781Hu01 Recombinant Annexin A11 (ANXA11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE781Hu01 Polyclonal Antibody to Annexin A11 (ANXA11) WB; IHC; ICC; IP.
MAE781Hu21 Monoclonal Antibody to Annexin A11 (ANXA11) WB; IHC; ICC; IP.
Assay Kits SEE781Hu ELISA Kit for Annexin A11 (ANXA11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Annexin A11 (ANXA11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Annexin A11 (ANXA11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Annexin A11 (ANXA11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Annexin A11 (ANXA11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Annexin A11 (ANXA11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Annexin A11 (ANXA11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Annexin A11 (ANXA11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Annexin A11 (ANXA11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Annexin A11 (ANXA11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Annexin A11 (ANXA11) ELISA Kit Customized Service Offer
  1. "The 56K autoantigen is identical to human annexin XI."J. Biol. Chem. 269:4240-4246(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Annexin A11 (ANXA11) gene structure as the progenitor of paralogous annexins and source of orthologous cDNA isoforms."Genomics 69:95-103(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner."Biochem. Biophys. Res. Commun. 291:1166-1172(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope."J. Biol. Chem. 278:20210-20216(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display."J. Biol. Chem. 278:33120-33126(2003) [PubMed] [Europe PMC] [Abstract]
  9. "Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis."J. Cell Biol. 165:813-822(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."J. Proteome Res. 5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
  11. "Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants."J. Biol. Chem. 283:9623-9632(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]