Perilipin 3 (PLIN3)

[Edit]

M6PRBP1; TIP47; PP17; Mannose-6-Phosphate Receptor Binding Protein 1; Placental Protein 17; 47 kDa mannose 6-phosphate receptor-binding protein; Cargo selection TIP47

Perilipin 3 (PLIN3)
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex.
Perilipin 3 interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport.
This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE041Hu01 Recombinant Perilipin 3 (PLIN3) Positive Control; Immunogen; SDS-PAGE; WB.
CPE041Hu21 OVA Conjugated Perilipin 3 (PLIN3) Immunogen; SDS-PAGE; WB.
Antibodies PAE041Hu01 Polyclonal Antibody to Perilipin 3 (PLIN3) WB; IHC; ICC; IP.
MAE041Hu21 Monoclonal Antibody to Perilipin 3 (PLIN3) WB; IHC; ICC; IP.
PAE041Hu08 Polyclonal Antibody to Perilipin 3 (PLIN3) WB; IHC; ICC; IP.
PAE041Mi08 Polyclonal Antibody to Perilipin 3 (PLIN3) WB; IHC; ICC; IP.
Assay Kits SEE041Hu ELISA Kit for Perilipin 3 (PLIN3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Perilipin 3 (PLIN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Perilipin 3 (PLIN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Perilipin 3 (PLIN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Perilipin 3 (PLIN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Perilipin 3 (PLIN3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Perilipin 3 (PLIN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Perilipin 3 (PLIN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Perilipin 3 (PLIN3) Polyclonal Antibody Customized Service Offer
Assay Kits SEE041Ra ELISA Kit for Perilipin 3 (PLIN3) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking."Cell 93:433-443(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and sequence analysis of cDNAs encoding human placental tissue protein 17 (PP17) variants."Eur. J. Biochem. 258:752-757(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and sequencing of human oncodevelopmental soluble placental tissue protein 17 (PP17): homology with adipophilin and the mouse adipose differentiation-related protein."Tumor Biol. 20:184-192(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Purification and characterization of two new soluble placental tissue proteins (PP13 and PP17)."Oncodev. Biol. Med. 4:343-350(1983) [PubMed] [Europe PMC] [Abstract]
  8. "Spatial integration of TIP47 and adipophilin in macrophage lipid bodies."J. Biol. Chem. 280:5789-5794(2005) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  15. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]