Nerve Growth Factor IB (NGFIB)

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GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3; DHR38; TIS1; Orphan nuclear receptor HMR; Testicular receptor 3; Nuclear receptor subfamily 4 group A member 1

Nerve Growth Factor IB (NGFIB)
NGFIB plays a key role in mediating inflammatory responses in macrophages. In addition, subcellular localization of the NGFIB protein appears to play a key role in the survival and death of cells.Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein has an atypical ligand-binding domain that is unlike the classical ligand-binding domain in most nuclear receptors. The classical domain contains a ligand-receiving pocket and co-activator site, both of which are lacking in the NR4A family. Where most nuclear receptors have a hydrophobic surface that results in a cleft, NGFI-B has a hydrophilic surface.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nerve Growth Factor IB (NGFIB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nerve Growth Factor IB (NGFIB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nerve Growth Factor IB (NGFIB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nerve Growth Factor IB (NGFIB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nerve Growth Factor IB (NGFIB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nerve Growth Factor IB (NGFIB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nerve Growth Factor IB (NGFIB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nerve Growth Factor IB (NGFIB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nerve Growth Factor IB (NGFIB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nerve Growth Factor IB (NGFIB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD963Ra01 Recombinant Nerve Growth Factor IB (NGFIB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD963Ra01 Polyclonal Antibody to Nerve Growth Factor IB (NGFIB) WB; IHC; ICC; IP.
MAD963Ra21 Monoclonal Antibody to Nerve Growth Factor IB (NGFIB) WB; IHC; ICC; IP.
Assay Kits SED963Ra ELISA Kit for Nerve Growth Factor IB (NGFIB) Enzyme-linked immunosorbent assay for Antigen Detection.
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